5WGD
| Estrogen Receptor Alpha Ligand Binding Domain in Complex with Estradiol and SRC2-LP1 | 分子名称: | (ACE)AILHKLLQDS(NH2), (ACE)HKILHKLLQDS(NH2), ESTRADIOL, ... | 著者 | Fanning, S.W, Speltz, T.E, Mayne, C.G, Siddiqui, Z, Greene, G.L, Tajkhorshid, E, Moore, T.W. | 登録日 | 2017-07-14 | 公開日 | 2018-06-13 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | A "cross-stitched" peptide with improved helicity and proteolytic stability. Org. Biomol. Chem., 16, 2018
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5WFT
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5F6Y
| Crystal structure of Ubc9 (K48/K49A/E54A) complexed with Fragment 2 (mercaptobenzoxazole) | 分子名称: | 5-chloranyl-3~{H}-1,3-benzoxazole-2-thione, SUMO-conjugating enzyme UBC9 | 著者 | Lountos, G.T, Hewitt, W.M, Zlotkowski, K, Dahlhauser, S, Saunders, L.B, Needle, D, Tropea, J.E, Zhan, C, Wei, G, Ma, B, Nussinov, R, Schneekloth, J.S.Jr, Waugh, D.S. | 登録日 | 2015-12-07 | 公開日 | 2016-04-27 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.14 Å) | 主引用文献 | Insights Into the Allosteric Inhibition of the SUMO E2 Enzyme Ubc9. Angew.Chem.Int.Ed.Engl., 55, 2016
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6WL5
| Crystal structure of EcmrR C-terminal domain | 分子名称: | 1,2-ETHANEDIOL, CETYL-TRIMETHYL-AMMONIUM, CHLORIDE ION, ... | 著者 | Yang, Y, Liu, C, Liu, B. | 登録日 | 2020-04-18 | 公開日 | 2021-04-07 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Structural visualization of transcription activated by a multidrug-sensing MerR family regulator. Nat Commun, 12, 2021
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6WNM
| The structure of Pf4r from a superinfective isolate of the filamentous phage Pf4 of Pseudomonas aeruginosa PA01 | 分子名称: | Pf4r, [(2R)-3-{[2-(carboxymethoxy)benzene-1-carbonyl]amino}-2-methoxypropyl](hydroxy)mercury | 著者 | Michie, K.A, Norrian, P, Duggin, I.G, McDougald, D, Rice, S.A. | 登録日 | 2020-04-22 | 公開日 | 2021-04-07 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | 主引用文献 | The Repressor C Protein, Pf4r, Controls Superinfection of Pseudomonas aeruginosa PAO1 by the Pf4 Filamentous Phage and Regulates Host Gene Expression. Viruses, 13, 2021
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6WPZ
| The structure of Pf4r from a superinfective isolate of the filamentous phage Pf4 of Pseudomonas aeruginosa PA01 | 分子名称: | CHLORIDE ION, Pf4r | 著者 | Michie, K.A, Norrian, P, Duggin, I.G, McDougald, D, Rice, S.A. | 登録日 | 2020-04-28 | 公開日 | 2021-04-07 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.993 Å) | 主引用文献 | The Repressor C Protein, Pf4r, Controls Superinfection of Pseudomonas aeruginosa PAO1 by the Pf4 Filamentous Phage and Regulates Host Gene Expression. Viruses, 13, 2021
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7TGQ
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5J0I
| De novo design of protein homo-oligomers with modular hydrogen bond network-mediated specificity | 分子名称: | Designed protein 2L6HC3_12 | 著者 | Sankaran, B, Zwart, P.H, Pereira, J.H, Baker, D, Boyken, S, Chen, Z, Groves, B, Langan, R.A, Oberdorfer, G, Ford, A, Gilmore, J, Xu, C, DiMaio, F, Seelig, G. | 登録日 | 2016-03-28 | 公開日 | 2016-05-25 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.202 Å) | 主引用文献 | De novo design of protein homo-oligomers with modular hydrogen-bond network-mediated specificity. Science, 352, 2016
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5EYM
| MEK1 IN COMPLEX WITH BI 847325 | 分子名称: | 3-[(3~{Z})-3-[[[4-[(dimethylamino)methyl]phenyl]amino]-phenyl-methylidene]-2-oxidanylidene-1~{H}-indol-6-yl]-~{N}-ethyl-prop-2-ynamide, CALCIUM ION, Dual specificity mitogen-activated protein kinase kinase 1 | 著者 | Bader, G, Reiser, U, Zahn, S.K, Treu, M. | 登録日 | 2015-11-25 | 公開日 | 2016-08-17 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Pharmacological Profile of BI 847325, an Orally Bioavailable, ATP-Competitive Inhibitor of MEK and Aurora Kinases. Mol.Cancer Ther., 15, 2016
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7LBQ
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7LBK
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7LBP
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7LBO
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8IOB
| Herg1a-herg1b closed state 1 | 分子名称: | Potassium voltage-gated channel subfamily H member 2 | 著者 | Zhang, M.F. | 登録日 | 2023-03-10 | 公開日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structure of Herg1a-herg1b closed state 1 To Be Published
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8IO4
| Herg1a-herg1b open state | 分子名称: | Potassium voltage-gated channel subfamily H member 2 | 著者 | Zhang, M.F. | 登録日 | 2023-03-10 | 公開日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structure of Herg1a-herg1b open state To Be Published
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5JNH
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8INL
| LSD1 in complex with S2172 | 分子名称: | 3-[3,5-bis(fluoranyl)-2-phenylmethoxy-phenyl]propanal, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | 著者 | Niwa, H, Sato, S, Umehara, T. | 登録日 | 2023-03-10 | 公開日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | 主引用文献 | LSD1 in complex with S2172 To Be Published
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6WQH
| Molecular basis for the ATPase-powered substrate translocation by the Lon AAA+ protease | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Ig2 substrate, Lon protease, ... | 著者 | Zhang, K, Li, S, Hsiehb, K, Sub, S, Pintilie, G, Chiu, W, Chang, C. | 登録日 | 2020-04-28 | 公開日 | 2021-06-09 | 最終更新日 | 2021-11-17 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Molecular basis for ATPase-powered substrate translocation by the Lon AAA+ protease. J.Biol.Chem., 297, 2021
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5FMQ
| Crystal structure of the mid, cap-binding, mid-link and 627 domains from avian influenza A virus polymerase PB2 subunit bound to M7GTP H32 crystal form | 分子名称: | 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, INFLUENZA A PB2 SUBUNIT | 著者 | Thierry, E, Pflug, A, Hart, D, Cusack, S. | 登録日 | 2015-11-07 | 公開日 | 2016-01-13 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Influenza Polymerase Can Adopt an Alternative Configuration Involving a Radical Repacking of Pb2 Domains. Mol.Cell, 61, 2016
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3WOA
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7A1G
| Structure of a crosslinked yeast ABCE1-bound 43S pre-initiation complex | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... | 著者 | Mackens-Kiani, T, Kratzat, H, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. | 登録日 | 2020-08-13 | 公開日 | 2020-10-14 | 最終更新日 | 2023-11-29 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes. Embo J., 40, 2021
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5FRH
| Solution structure of oxidised RsrA | 分子名称: | ANTI-SIGMA FACTOR RSRA | 著者 | Zdanowski, K, Pecqueur, L, Werner, J, Potts, J.R, Kleanthous, C. | 登録日 | 2015-12-17 | 公開日 | 2016-08-03 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | The Anti-Sigma Factor Rsra Responds to Oxidative Stress by Reburying its Hydrophobic Core. Nat.Commun., 7, 2016
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6UMX
| Structural basis for specific inhibition of extracellular activation of pro/latent myostatin by SRK-015 | 分子名称: | GL29H4-16 Fab Heavy Chain,GL29H4-16 Fab Heavy Chain, GL29H4-16 Fab Light Chain,GL29H4-16 Fab Light Chain, GLYCEROL, ... | 著者 | Dagbay, K.B, Treece, E, Streich Jr, F.C, Jackson, J.W, Faucette, R.R, Nikiforov, A, Lin, S.C, Bostion, C.J, Nicholls, S.B, Capili, A.D, Carven, G.J. | 登録日 | 2019-10-10 | 公開日 | 2020-02-26 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | 主引用文献 | Structural basis of specific inhibition of extracellular activation of pro- or latent myostatin by the monoclonal antibody SRK-015. J.Biol.Chem., 295, 2020
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5FML
| Crystal structure of the endonuclease from the PA subunit of influenza B virus bound to the PB2 subunit NLS peptide | 分子名称: | GLYCEROL, MAGNESIUM ION, PA SUBUNIT OF INFLUENZA B POLYMERASE, ... | 著者 | Guilligay, D, Gaudon, S, Cusack, S. | 登録日 | 2015-11-06 | 公開日 | 2016-01-13 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Influenza Polymerase Can Adopt an Alternative Configuration Involving a Radical Repacking of Pb2 Domains. Mol.Cell, 61, 2016
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8PK6
| INTS13 complex with ZNF655 | 分子名称: | Integrator complex subunit 13, Zinc finger protein 655 | 著者 | Sabath, K, Jonas, S. | 登録日 | 2023-06-25 | 公開日 | 2024-07-03 | 最終更新日 | 2024-07-24 | 実験手法 | X-RAY DIFFRACTION (3.21 Å) | 主引用文献 | Basis of gene-specific transcription regulation by the Integrator complex. Mol.Cell, 84, 2024
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