7TGQ

Zinc finger antiviral protein (ZAP) central domain bound to ADP-ribose

Summary for 7TGQ

• Entry DOI: 10.2210/pdb7tgq/pdb
• Related: 7KZH
• Descriptor: Zinc finger CCCH-type antiviral protein 1, ZINC ION, ADENOSINE-5-DIPHOSPHORIBOSE, ... (5 entities in total)
• Functional Keywords: restriction factor, antiviral protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 24129.22

Authors

Pornillos, O.P. (deposition date: 2022-01-09, release date: 2022-02-02, Last modification date: 2023-10-25)

• Primary citation: Xue, G.,Braczyk, K.,Goncalves-Carneiro, D.,Dawidziak, D.M.,Sanchez, K.,Ong, H.,Wan, Y.,Zadrozny, K.K.,Ganser-Pornillos, B.K.,Bieniasz, P.D.,Pornillos, O.; Poly(ADP-ribose) potentiates ZAP antiviral activity.; Plos Pathog., 18:e1009202-e1009202, 2022; PubMed: 35130321; DOI: 10.1371/journal.ppat.1009202

Experimental method

X-RAY DIFFRACTION (2 Å)