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7Q6A
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BU of 7q6a by Molmil
Crystal structure of Chaetomium thermophilum C30S Ahp1 in post-reaction state
分子名称: GLYCEROL, SULFATE ION, Thioredoxin domain-containing protein
著者Ravichandran, K.E, Wilk, P, Grudnik, P, Glatt, S.
登録日2021-11-05
公開日2022-08-24
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献E2/E3-independent ubiquitin-like protein conjugation by Urm1 is directly coupled to cysteine persulfidation.
Embo J., 41, 2022
7QS8
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BU of 7qs8 by Molmil
Structural insight into the Scribble PDZ domains interaction with the oncogenic Human T-cell lymphotrophic virus-1 (HTLV-1) Tax1
分子名称: Protein Tax-1, Protein scribble homolog
著者Javorsky, A, Soares da Costa, T.P, Mackie, E.R, Humbert, P.O, Kvansakul, M.
登録日2022-01-13
公開日2022-09-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural insight into the Scribble PDZ domains interaction with the oncogenic Human T-cell lymphotrophic virus-1 (HTLV-1) Tax1 PBM.
Febs J., 290, 2023
7JPY
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BU of 7jpy by Molmil
Crystal structure of the SARS-CoV-2 main protease in its apo-form
分子名称: 3C-like proteinase
著者Yang, K, Liu, W.
登録日2020-08-10
公開日2020-12-23
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献A Quick Route to Multiple Highly Potent SARS-CoV-2 Main Protease Inhibitors*.
Chemmedchem, 16, 2021
2N8H
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BU of 2n8h by Molmil
Structural basis for the inhibition of voltage-gated sodium channels with conotoxin-muOxi-GVIIJ
分子名称: conotoxin-muOxi-GVIIJ
著者Green, B.R, Chhabra, S, Norton, R.S.
登録日2015-10-15
公開日2016-02-03
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structural Basis for the Inhibition of Voltage-gated Sodium Channels by Conotoxin mu O-GVIIJ.
J.Biol.Chem., 291, 2016
7QWX
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BU of 7qwx by Molmil
Empty capsid of Saccharomyces cerevisiae virus L-BCLa
分子名称: Major capsid protein
著者Grybchuk, D, Prochazkova, M, Fuzik, T, Konovalovas, A, Serva, S, Yurchenko, V, Plevka, P.
登録日2022-01-26
公開日2022-09-07
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structures of L-BC virus and its open particle provide insight into Totivirus capsid assembly.
Commun Biol, 5, 2022
7JQ4
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BU of 7jq4 by Molmil
Structure of the SARS-CoV-2 main protease in complex with inhibitor MPI7
分子名称: 3C-like proteinase, N-[(benzyloxy)carbonyl]-O-tert-butyl-L-threonyl-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-phenylalaninamide
著者Yang, K, Liu, W.
登録日2020-08-10
公開日2020-12-23
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献A Quick Route to Multiple Highly Potent SARS-CoV-2 Main Protease Inhibitors*.
Chemmedchem, 16, 2021
2Y29
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BU of 2y29 by Molmil
Structure of segment KLVFFA from the amyloid-beta peptide (Ab, residues 16-21), alternate polymorph III
分子名称: AMYLOID BETA A4 PROTEIN
著者Colletier, J, Laganowsky, A, Sawaya, M.R, Eisenberg, D.
登録日2010-12-14
公開日2011-10-26
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Molecular Basis for Amyloid-{Beta} Polymorphism.
Proc.Natl.Acad.Sci.USA, 108, 2011
7ER6
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BU of 7er6 by Molmil
Crystal structure of human Biliverdin IX-beta reductase B
分子名称: Flavin reductase (NADPH), NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFATE ION
著者Griesinger, C, Lee, D, Ryu, K.S, Kim, M, Ha, J.H.
登録日2021-05-06
公開日2022-01-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Repositioning Food and Drug Administration-Approved Drugs for Inhibiting Biliverdin IX beta Reductase B as a Novel Thrombocytopenia Therapeutic Target.
J.Med.Chem., 65, 2022
7JVK
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BU of 7jvk by Molmil
Structure of the M101A variant of the SidA ornithine hydroxylase with the FAD in the "out" conformation
分子名称: ACETATE ION, CALCIUM ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Tanner, J.J, Campbell, A.C.
登録日2020-08-21
公開日2020-12-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Determinants of Flavin Dynamics in a Class B Monooxygenase.
Biochemistry, 59, 2020
3IOC
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BU of 3ioc by Molmil
Crystal Structure of Mycobacterium Tuberculosis Pantothenate Synthetase at 2.50 Ang resolution in complex with 5'-deoxy-5'-(benzyldisulfanyl)-adenosine
分子名称: (2R,3R,4S,5S)-2-(6-amino-9H-purin-9-yl)-5-[(benzyldisulfanyl)methyl]tetrahydrofuran-3,4-diol, GLYCEROL, Pantothenate synthetase
著者Ciulli, A, Scott, D.E, Abell, C.
登録日2009-08-14
公開日2009-12-01
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A Fragment-Based Approach to Probing Adenosine Recognition Sites by Using Dynamic Combinatorial Chemistry
Chembiochem, 10, 2009
7ER7
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BU of 7er7 by Molmil
Crystal structure of hyman Biliverdin IX-beta reductase B with Tamibarotene (A80)
分子名称: 4-[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbamoyl]benzoic acid, Flavin reductase (NADPH), NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Griesinger, C, Lee, D, Ryu, K.S, Kim, M, Ha, J.H.
登録日2021-05-06
公開日2022-01-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Repositioning Food and Drug Administration-Approved Drugs for Inhibiting Biliverdin IX beta Reductase B as a Novel Thrombocytopenia Therapeutic Target.
J.Med.Chem., 65, 2022
7AZG
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BU of 7azg by Molmil
DNA polymerase sliding clamp from Escherichia coli with peptide 4 bound
分子名称: Beta sliding clamp, Peptide 4
著者Monsarrat, C, Compain, G, Andre, C, Martiel, I, Engilberge, S, Olieric, V, Wolff, P, Brillet, K, Landolfo, M, Silva da Veiga, C, Wagner, J, Guichard, G, Burnouf, D.Y.
登録日2020-11-16
公開日2021-12-01
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.92 Å)
主引用文献Iterative Structure-Based Optimization of Short Peptides Targeting the Bacterial Sliding Clamp.
J.Med.Chem., 64, 2021
2IDA
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BU of 2ida by Molmil
Solution NMR Structure of Protein RPA1320 from Rhodopseudomonas Palustris. Northeast Structural Genomics Consortium Target RpT3; Ontario Center for Structural Proteomics Target RP1313.
分子名称: Hypothetical protein, ZINC ION
著者Lemak, A, Yee, A, Lukin, J.A, Karra, M, Gutmanas, A, Guido, V, Arrowsmith, C.H, Northeast Structural Genomics Consortium (NESG)
登録日2006-09-14
公開日2006-10-24
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of RPA1320
To be Published
7FFC
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BU of 7ffc by Molmil
Diarylpentanoid-producing polyketide synthase (A210E mutant)
分子名称: GLYCEROL, Type III polyketide synthase
著者Morita, H, Wong, C.P, Liu, Q, Kodama, T, Lee, Y, Nakashima, Y.
登録日2021-07-23
公開日2022-01-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Identification of a diarylpentanoid-producing polyketide synthase revealing an unusual biosynthetic pathway of 2-(2-phenylethyl)chromones in agarwood.
Nat Commun, 13, 2022
7ATR
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BU of 7atr by Molmil
The Crystal Structure of YejA - an ABC Peptide Transporter Receptor
分子名称: GLYCEROL, Uncharacterized protein YejA
著者Ackroyd, B.K, Dodson, E.J, Wilkinson, A.J, Thomas, G.T.
登録日2020-10-30
公開日2021-11-17
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献The Crystal Structure of YejA - an ABC Peptide Transporter Receptor
To Be Published
7ERD
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BU of 7erd by Molmil
Crystal structure of human Biliverdin IX-beta reductase B with Flunixin Meglumin (FMG)
分子名称: 2-[[2-methyl-3-(trifluoromethyl)phenyl]amino]pyridine-3-carboxylic acid, Flavin reductase (NADPH), NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Griesinger, C, Lee, D, Ryu, K.S, Kim, M, Ha, J.H.
登録日2021-05-06
公開日2022-01-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Repositioning Food and Drug Administration-Approved Drugs for Inhibiting Biliverdin IX beta Reductase B as a Novel Thrombocytopenia Therapeutic Target.
J.Med.Chem., 65, 2022
2MW2
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BU of 2mw2 by Molmil
Hha-H-NS46 charge zipper complex
分子名称: DNA-binding protein H-NS, Hemolysin expression-modulating protein Hha
著者Cordeiro, T.N, Garcia, J, Bernado, P, Millet, O, Pons, M.
登録日2014-10-24
公開日2015-07-29
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献A Three-protein Charge Zipper Stabilizes a Complex Modulating Bacterial Gene Silencing.
J. Biol. Chem., 290, 2015
5LLI
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BU of 5lli by Molmil
pVHL:EloB:EloC in complex with VH298
分子名称: (2~{S},4~{R})-1-[(2~{S})-2-[(1-cyanocyclopropyl)carbonylamino]-3,3-dimethyl-butanoyl]-~{N}-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]-4-oxidanyl-pyrrolidine-2-carboxamide, Transcription elongation factor B polypeptide 1, Transcription elongation factor B polypeptide 2, ...
著者Gadd, M.S, Soares, P, Galdeano, C, Ciulli, A.
登録日2016-07-27
公開日2016-11-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Potent and selective chemical probe of hypoxic signalling downstream of HIF-alpha hydroxylation via VHL inhibition.
Nat Commun, 7, 2016
7JZ2
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BU of 7jz2 by Molmil
Succinate: quinone oxidoreductase SQR from E.coli K12
分子名称: 1,2-Distearoyl-sn-glycerophosphoethanolamine, FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, ...
著者Lyu, M, Su, C.-C, Morgan, C.E, Bolla, J.R, Robinson, C.V, Yu, E.W.
登録日2020-09-01
公開日2021-01-20
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献A 'Build and Retrieve' methodology to simultaneously solve cryo-EM structures of membrane proteins.
Nat.Methods, 18, 2021
2MWO
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BU of 2mwo by Molmil
Solution structure of 53BP1 tandem Tudor domains in complex with a p53K370me2 peptide
分子名称: Cellular tumor antigen p53, Tumor suppressor p53-binding protein 1
著者Cui, G, Botuyan, M.V, Mer, G.
登録日2014-11-15
公開日2014-12-10
最終更新日2015-03-18
実験手法SOLUTION NMR
主引用文献Structural Plasticity of Methyllysine Recognition by the Tandem Tudor Domain of 53BP1.
Structure, 23, 2015
3IF9
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BU of 3if9 by Molmil
Crystal structure of Glycine Oxidase G51S/A54R/H244A mutant in complex with inhibitor glycolate
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GLYCOLIC ACID, Glycine oxidase
著者Pedotti, M, Rosini, E, Molla, G, Moschetti, T, Vallone, B, Savino, C, Pollegioni, L.
登録日2009-07-24
公開日2009-10-27
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Glyphosate resistance by engineering the flavoenzyme glycine oxidase.
J.Biol.Chem., 284, 2009
2XXZ
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BU of 2xxz by Molmil
Crystal structure of the human JMJD3 jumonji domain
分子名称: 1,2-ETHANEDIOL, 8-hydroxyquinoline-5-carboxylic acid, LYSINE-SPECIFIC DEMETHYLASE 6B, ...
著者Che, K.H, Yue, W.W, Krojer, T, Muniz, J.R.C, Ng, S.S, Tumber, A, Daniel, M, Burgess-Brown, N, Savitsky, P, Ugochukwu, E, Filippakopoulos, P, Arrowsmith, C, Weigelt, J, Edwards, A, Bountra, C, Oppermann, U.
登録日2010-11-12
公開日2010-11-24
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of the Human Jmjd3 Jumonji Domain
To be Published
7AZV
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BU of 7azv by Molmil
Crystal structure of a shortened IpgC variant in complex with 4-(trifluoromethyl)benzene-1-carboximidamide
分子名称: 4-(trifluoromethyl)benzenecarboximidamide, CHLORIDE ION, Chaperone protein IpgC, ...
著者Gardonyi, M, Heine, A, Klebe, G.
登録日2020-11-17
公開日2021-12-01
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Crystal structure of a shortened IpgC variant in complex with 4-(trifluoromethyl)benzene-1-carboximidamide
To be published
2XKM
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BU of 2xkm by Molmil
Consensus structure of Pf1 filamentous bacteriophage from X-ray fibre diffraction and solid-state NMR
分子名称: CAPSID PROTEIN G8P
著者Straus, S.K, P Scott, W.R, Schwieters, C.D, Marvin, D.A.
登録日2010-07-09
公開日2010-11-24
最終更新日2023-12-20
実験手法FIBER DIFFRACTION (3.3 Å), SOLID-STATE NMR
主引用文献Consensus Structure of Pf1 Filamentous Bacteriophage from X-Ray Fibre Diffraction and Solid-State NMR.
Eur.Biophys.J., 40, 2011
3IS7
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BU of 3is7 by Molmil
Structure of mineralized Bfrb from Pseudomonas aeruginosa to 2.1A Resolution
分子名称: Bacterioferritin, POTASSIUM ION, PROTOPORPHYRIN IX CONTAINING FE
著者Lovell, S, Weeratunga, S.K, Battaile, K.P, Rivera, M.
登録日2009-08-25
公開日2010-02-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Studies of Bacterioferritin B from Pseudomonas aeruginosa Suggest a Gating Mechanism for Iron Uptake via the Ferroxidase Center
Biochemistry, 49, 2010

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件を2024-08-21に公開中

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