2XXZ

Crystal structure of the human JMJD3 jumonji domain

Summary for 2XXZ

Related2XUE
DescriptorLYSINE-SPECIFIC DEMETHYLASE 6B, NICKEL (II) ION, SODIUM ION, ... (6 entities in total)
Functional Keywordsoxidoreductase, histone demethylation, oxygenase, chromatin modification
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationNucleus  O15054
Total number of polymer chains2
Total molecular weight76261.64
Authors
Primary citation
Che, K.H.,Yue, W.W.,Krojer, T.,Muniz, J.R.C.,Ng, S.S.,Tumber, A.,Daniel, M.,Burgess-Brown, N.,Savitsky, P.,von Delft, F.,Ugochukwu, E.,Filippakopoulos, P.,Arrowsmith, C.,Weigelt, J.,Edwards, A.,Bountra, C.,Oppermann, U.
Crystal Structure of the Human Jmjd3 Jumonji Domain
To be Published,
Experimental method
X-RAY DIFFRACTION (1.8 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.245601.0%3.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2xxz
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Molmil generated image of 2xxz
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Molmil generated image of 2xxz
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More Biological unit images

Molmil generated image of 2xxz
no rotation
Molmil generated image of 2xxz
rotated about x axis by 90°
Molmil generated image of 2xxz
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (2xxz.pdb2.gz [101.98 KB])
Coordinate files for Biological unit (2xxz.pdb1.gz [104.44 KB])