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2XUE

CRYSTAL STRUCTURE OF JMJD3

Summary for 2XUE
Entry DOI10.2210/pdb2xue/pdb
DescriptorLYSINE-SPECIFIC DEMETHYLASE 6B, ZINC ION, SULFATE ION, ... (6 entities in total)
Functional Keywordsoxidoreductase, histone methylase
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationNucleus (Probable): O15054
Total number of polymer chains2
Total formula weight116565.03
Authors
Chung, C.,Rowland, P.,Mosley, J.,Thomas, P.J. (deposition date: 2010-10-19, release date: 2011-12-28, Last modification date: 2012-08-29)
Primary citationKruidenier, L.,Chung, C.,Cheng, Z.,Liddle, J.,Che, K.,Joberty, G.,Bantscheff, M.,Bountra, C.,Bridges, A.,Diallo, H.,Eberhard, D.,Hutchinson, S.,Jones, E.,Katso, R.,Leveridge, M.,Mander, P.K.,Mosley, J.,Ramirez-Molina, C.,Rowland, P.,Schofield, C.J.,Sheppard, R.J.,Smith, J.E.,Swales, C.,Tanner, R.,Thomas, P.,Tumber, A.,Drewes, G.,Oppermann, U.,Patel, D.J.,Lee, K.,Wilson, D.M.
A Selective Jumonji H3K27 Demethylase Inhibitor Modulates the Proinflammatory Macrophage Response
Nature, 488:404-, 2012
Cited by
PubMed: 22842901
DOI: 10.1038/NATURE11262
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation

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