2XUE

CRYSTAL STRUCTURE OF JMJD3

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	LYSINE-SPECIFIC DEMETHYLASE 6B	polymer	509	57919.1	2	UniProt (O15054) Pfam (PF02373) Pfam (PF21322) Pfam (PF21326)	HOMO SAPIENS (HUMAN)	JMJD3, JMJC DOMAIN-CONTAINING PROTEIN 3, JUMONJI DOMAIN-CONTAINING PROTEIN 3, LYSINE DEMETHYLASE 6B
2	C, G (A, B)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
3	D, H (A, B)	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
4	E, I (A, B)	FE (III) ION	non-polymer		55.8	2	Chemie (FE)
5	F, J (A, B)	2-OXOGLUTARIC ACID	non-polymer		146.1	2	Chemie (AKG)
6	K, L (A, B)	water	water		18.0	560	Chemie (HOH)

Sequence modifications

A, B: 1141 - 1643 (UniProt: O15054)

PDB	External Database	Details
His 1644	-	expression tag
His 1645	-	expression tag
His 1646	-	expression tag
His 1647	-	expression tag
His 1648	-	expression tag
His 1649	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	115838.2
Non-Polymers*	Number of molecules	8
	Total formula weight	726.8
All*	Total formula weight	116565.0

*Water molecules are not included.