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2XXZ

Crystal structure of the human JMJD3 jumonji domain

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BLYSINE-SPECIFIC DEMETHYLASE 6Bpolymer33237686.92UniProt (O15054)
Pfam (PF02373)
In PDB
HOMO SAPIENS (HUMAN)JMJD3, JMJC DOMAIN-CONTAINING PROTEIN 3, JUMONJI DOMAIN-CONTAINING PROTEIN 3, LYSINE DEMETHYLASE 6B
2A, BNICKEL (II) IONnon-polymer58.73Chemie (NI)
3ASODIUM IONnon-polymer23.01Chemie (NA)
4A, B1,2-ETHANEDIOLnon-polymer62.15Chemie (EDO)
5A, B8-hydroxyquinoline-5-carboxylic acidnon-polymer189.22Chemie (8XQ)
6waterwater18.0319Chemie (HOH)
Sequence modifications
A, B: 1173 - 1502 (UniProt: O15054)
PDBExternal DatabaseDetails
Ser 1171-expression tag
Met 1172-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight75373.9
Non-Polymers*Number of molecules11
Total formula weight887.7
All*Total formula weight76261.6
*Water molecules are not included.

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PDB entries from 2024-04-17

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