2XXZ
Crystal structure of the human JMJD3 jumonji domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | LYSINE-SPECIFIC DEMETHYLASE 6B | polymer | 332 | 37686.9 | 2 | UniProt (O15054) Pfam (PF02373) | HOMO SAPIENS (HUMAN) | JMJD3, JMJC DOMAIN-CONTAINING PROTEIN 3, JUMONJI DOMAIN-CONTAINING PROTEIN 3, LYSINE DEMETHYLASE 6B |
| 2 | C, E, K (A, B) | NICKEL (II) ION | non-polymer | 58.7 | 3 | Chemie (NI) PubChem (934) | |||
| 3 | D (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) PubChem (923) | |||
| 4 | F, G, H, I, L (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 5 | J, M (A, B) | 8-hydroxyquinoline-5-carboxylic acid | non-polymer | 189.2 | 2 | Chemie (8XQ) PubChem (459617) | |||
| 6 | N, O (A, B) | water | water | 18.0 | 319 | Chemie (HOH) |
Sequence modifications
A, B: 1173 - 1502 (UniProt: O15054)
| PDB | External Database | Details |
|---|---|---|
| Ser 1171 | - | expression tag |
| Met 1172 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 75373.9 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 887.7 | |
| All* | Total formula weight | 76261.6 |
