Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005634 | cellular_component | nucleus |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0071557 | biological_process | histone H3-K27 demethylation |
| A | 0071558 | molecular_function | histone H3-tri/di-methyl-lysine-27 demethylase activity |
| B | 0005634 | cellular_component | nucleus |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0071557 | biological_process | histone H3-K27 demethylation |
| B | 0071558 | molecular_function | histone H3-tri/di-methyl-lysine-27 demethylase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NI A 2494 |
| Chain | Residue |
| A | HIS1387 |
| A | GLU1389 |
| A | HOH2098 |
| A | HOH2103 |
| A | 8XQ3001 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NI A 2500 |
| Chain | Residue |
| A | HOH2060 |
| B | HOH2150 |
| A | HOH2013 |
| A | HOH2015 |
| A | HOH2054 |
| A | HOH2059 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NI B 2500 |
| Chain | Residue |
| B | HIS1387 |
| B | GLU1389 |
| B | HOH2083 |
| B | HOH2155 |
| B | 8XQ3001 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA A 2495 |
| Chain | Residue |
| A | GLU1287 |
| B | GLU1188 |
| B | HOH2011 |
| B | HOH2012 |
| B | HOH2013 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 2496 |
| Chain | Residue |
| A | ILE1185 |
| A | TYR1186 |
| B | GLN1200 |
| B | HOH2020 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 2497 |
| Chain | Residue |
| A | ASP1204 |
| A | GLN1489 |
| A | HOH2163 |
| A | HOH2164 |
| B | PRO1183 |
| B | SER1184 |
| B | PHE1201 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 2498 |
| Chain | Residue |
| A | ASP1330 |
| A | MET1370 |
| A | HOH2015 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 2501 |
| Chain | Residue |
| A | ARG1191 |
| B | LYS1190 |
| B | ARG1191 |
| B | TYR1497 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 2499 |
| Chain | Residue |
| A | SER1227 |
| A | THR1228 |
| A | GLY1401 |
| A | ASN1476 |
| site_id | BC1 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE 8XQ A 3001 |
| Chain | Residue |
| A | TYR1376 |
| A | LYS1378 |
| A | THR1384 |
| A | HIS1387 |
| A | GLU1389 |
| A | ASN1397 |
| A | TRP1407 |
| A | ILE1461 |
| A | HIS1467 |
| A | ASN1477 |
| A | HOH2103 |
| A | NI2494 |
| site_id | BC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE 8XQ B 3001 |
| Chain | Residue |
| B | TYR1376 |
| B | LYS1378 |
| B | THR1384 |
| B | HIS1387 |
| B | GLU1389 |
| B | ASN1397 |
| B | TRP1407 |
| B | HIS1467 |
| B | HOH2091 |
| B | HOH2155 |
| B | NI2500 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"O14607","evidenceCode":"ECO:0000250"}]} |
2XXZ
