7T08
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![BU of 7t08 by Molmil](/molmil-images/mine/7t08) | Cryptococcus neoformans protein farnesyltransferase in complex with FPP and inhibitor 2q | 分子名称: | (2R)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid, 1,2-ETHANEDIOL, 4-{[5-({(2S)-2-butyl-5-oxo-4-[3-(trifluoromethoxy)phenyl]piperazin-1-yl}methyl)-1H-imidazol-1-yl]methyl}-2-fluorobenzonitrile, ... | 著者 | Wang, Y, Shi, Y, Beese, L.S. | 登録日 | 2021-11-29 | 公開日 | 2022-11-09 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.803 Å) | 主引用文献 | Structure-Guided Discovery of Potent Antifungals that Prevent Ras Signaling by Inhibiting Protein Farnesyltransferase. J.Med.Chem., 65, 2022
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2XP5
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![BU of 2xp5 by Molmil](/molmil-images/mine/2xp5) | DISCOVERY OF CELL-ACTIVE PHENYL-IMIDAZOLE PIN1 INHIBITORS BY STRUCTURE-GUIDED FRAGMENT EVOLUTION | 分子名称: | 5-METHYL-2-PHENYL-1H-IMIDAZOLE-4-CARBOXYLIC ACID, DODECAETHYLENE GLYCOL, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE NIMA-INTERACTING 1 | 著者 | Potter, A, Oldfield, V, Nunns, C, Fromont, C, Ray, S, Northfield, C.J, Bryant, C.J, Scrace, S.F, Robinson, D, Matossova, N, Baker, L, Dokurno, P, Surgenor, A.E, Davis, B.E, Richardson, C.M, Murray, J.B, Moore, J.D. | 登録日 | 2010-08-25 | 公開日 | 2011-01-12 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Discovery of Cell-Active Phenyl-Imidazole Pin1 Inhibitors by Structure-Guided Fragment Evolution. Bioorg.Med.Chem.Lett., 20, 2010
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3ITT
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![BU of 3itt by Molmil](/molmil-images/mine/3itt) | Crystal structure of Pseudomonas stutzeri L-rhamnose isomerase mutant S329K in complex with L-rhamnose | 分子名称: | L-RHAMNOSE, L-rhamnose isomerase, MANGANESE (II) ION | 著者 | Yoshida, H, Yamaji, M, Ishii, T, Izumori, K, Kamitori, S. | 登録日 | 2009-08-28 | 公開日 | 2010-02-02 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Catalytic reaction mechanism of Pseudomonas stutzeri l-rhamnose isomerase deduced from X-ray structures Febs J., 277, 2010
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7SP4
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![BU of 7sp4 by Molmil](/molmil-images/mine/7sp4) | In situ cryo-EM structure of bacteriophage Sf6 gp3:gp7:gp5 complex in conformation 2 at 3.71A resolution | 分子名称: | Gene 3 protein, Gene 5 protein, Gene 7 protein | 著者 | Li, F, Cingolani, G, Hou, C, Yang, R. | 登録日 | 2021-11-02 | 公開日 | 2022-11-09 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.71 Å) | 主引用文献 | High-resolution cryo-EM structure of the Shigella virus Sf6 genome delivery tail machine. Sci Adv, 8, 2022
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7QKJ
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![BU of 7qkj by Molmil](/molmil-images/mine/7qkj) | |
7SVU
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![BU of 7svu by Molmil](/molmil-images/mine/7svu) | TnsBctd-TnsC-TniQ complex | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, DNA (28-MER), DNA (29-MER), ... | 著者 | Park, J, Tsai, A.W.T, Kellogg, E.H. | 登録日 | 2021-11-19 | 公開日 | 2022-11-23 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structures of the holo CRISPR RNA-guided transposon integration complex Nature, 613, 2023
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7QDN
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![BU of 7qdn by Molmil](/molmil-images/mine/7qdn) | |
7TD5
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![BU of 7td5 by Molmil](/molmil-images/mine/7td5) | Structure of human PRC2-EZH1 containing phosphorylated SUZ12 | 分子名称: | Histone-lysine N-methyltransferase EZH1, Polycomb protein EED, Polycomb protein SUZ12, ... | 著者 | Gong, L, Jiao, L, Liu, X. | 登録日 | 2021-12-30 | 公開日 | 2022-11-16 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.994 Å) | 主引用文献 | CK2-mediated phosphorylation of SUZ12 promotes PRC2 function by stabilizing enzyme active site. Nat Commun, 13, 2022
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3IVX
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![BU of 3ivx by Molmil](/molmil-images/mine/3ivx) | Crystal structure of pantothenate synthetase in complex with 2-(2-(benzofuran-2-ylsulfonylcarbamoyl)-5-methoxy-1H-indol-1-yl)acetic acid | 分子名称: | 1,2-ETHANEDIOL, ETHANOL, GLYCEROL, ... | 著者 | Silvestre, H.L, Hung, A.W, Wen, S, Ciulli, A, Blundell, T.L, Abell, C. | 登録日 | 2009-09-02 | 公開日 | 2009-10-13 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | Application of fragment growing and fragment linking to the discovery of inhibitors of Mycobacterium tuberculosis pantothenate synthetase. Angew.Chem.Int.Ed.Engl., 48, 2009
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2MD0
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![BU of 2md0 by Molmil](/molmil-images/mine/2md0) | Solution structure of ShK-like immunomodulatory peptide from Ancylostoma caninum (hookworm) | 分子名称: | AcK1 | 著者 | Chhabra, S, Swarbrick, J.D, Mohanty, B, Chang, S.C, Chandy, G.K, Pennington, M.W, Norton, R.S. | 登録日 | 2013-08-28 | 公開日 | 2014-07-02 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Kv1.3 channel-blocking immunomodulatory peptides from parasitic worms: implications for autoimmune diseases. Faseb J., 28, 2014
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2XW1
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7AZA
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![BU of 7aza by Molmil](/molmil-images/mine/7aza) | Perdeuterated E65Q-TIM complexed with PHOSPHOGLYCOLOHYDROXAMATE | 分子名称: | PHOSPHOGLYCOLOHYDROXAMIC ACID, Triosephosphate isomerase | 著者 | Kelpsas, V, Caldararu, O, von Wachenfeldt, C, Oksanen, E. | 登録日 | 2020-11-16 | 公開日 | 2021-07-28 | 最終更新日 | 2024-05-01 | 実験手法 | NEUTRON DIFFRACTION (1.1 Å), X-RAY DIFFRACTION | 主引用文献 | Neutron structures of Leishmania mexicana triosephosphate isomerase in complex with reaction-intermediate mimics shed light on the proton-shuttling steps. Iucrj, 8, 2021
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8Q84
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![BU of 8q84 by Molmil](/molmil-images/mine/8q84) | |
2M9V
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![BU of 2m9v by Molmil](/molmil-images/mine/2m9v) | |
7B1Z
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7AZ4
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![BU of 7az4 by Molmil](/molmil-images/mine/7az4) | Perdeuterated E65Q-TIM complexed with 2-PHOSPHOGLYCOLIC ACID | 分子名称: | 2-PHOSPHOGLYCOLIC ACID, Triosephosphate isomerase | 著者 | Kelpsas, V, Caldararu, O, von Wachenfeldt, C, Oksanen, E. | 登録日 | 2020-11-16 | 公開日 | 2021-07-28 | 最終更新日 | 2024-05-01 | 実験手法 | NEUTRON DIFFRACTION (1.15 Å), X-RAY DIFFRACTION | 主引用文献 | Neutron structures of Leishmania mexicana triosephosphate isomerase in complex with reaction-intermediate mimics shed light on the proton-shuttling steps. Iucrj, 8, 2021
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7KMX
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![BU of 7kmx by Molmil](/molmil-images/mine/7kmx) | The capsid of Myoviridae Phage XM1 | 分子名称: | Major capsid protein, Minor capsid protein | 著者 | Wang, Z, Klose, T, Jiang, W, Kuhn, R.J. | 登録日 | 2020-11-03 | 公開日 | 2021-11-10 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structure of Vibrio phage XM1, a simple contractile DNA injection machine Biorxiv, 2021
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7SPU
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![BU of 7spu by Molmil](/molmil-images/mine/7spu) | In situ cryo-EM structure of bacteriophage Sf6 gp3:gp7:gp5 complex in conformation 1 at 3.73A resolution | 分子名称: | Gene 3 protein, Gene 5 protein, Gene 7 protein | 著者 | Li, F, Cingolani, G, Hou, C, Yang, R. | 登録日 | 2021-11-03 | 公開日 | 2022-11-23 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.73 Å) | 主引用文献 | High-resolution cryo-EM structure of the Shigella virus Sf6 genome delivery tail machine. Sci Adv, 8, 2022
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2XZU
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![BU of 2xzu by Molmil](/molmil-images/mine/2xzu) | CRYSTAL STRUCTURE OF A COMPLEX BETWEEN THE WILD-TYPE LACTOCOCCUS LACTIS FPG (MUTM) AND AN OXIDIZED PYRIMIDINE CONTAINING DNA AT 310K | 分子名称: | 5'-D(*CP*TP*CP*TP*TP*TP*VETP*TP*TP*TP*CP*TP*CP*G)-3', 5'-D(GP*CP*GP*AP*GP*AP*AP*AP*CP*AP*AP*AP*G*A)-3', FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE, ... | 著者 | Lebihan, Y.V, Izquierdo, M.A, Coste, F, Culard, F, Gehrke, T.H, Essalhi, K, Aller, P, Carrel, T, Castaing, B. | 登録日 | 2010-11-29 | 公開日 | 2011-10-05 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | 5-Hydroxy-5-Methylhydantoin DNA Lesion, a Molecular Trap for DNA Glycosylases Nucleic Acids Res., 39, 2011
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7B0I
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![BU of 7b0i by Molmil](/molmil-images/mine/7b0i) | Structure of a minimal SF3B core in complex with spliceostatin A (form II) | 分子名称: | PHD finger-like domain-containing protein 5A, Splicing factor 3B subunit 1, Splicing factor 3B subunit 3,Splicing factor 3B subunit 3,Splicing factor 3B subunit 3, ... | 著者 | Cretu, C, Pena, V. | 登録日 | 2020-11-19 | 公開日 | 2021-08-04 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural basis of intron selection by U2 snRNP in the presence of covalent inhibitors. Nat Commun, 12, 2021
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7KFQ
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![BU of 7kfq by Molmil](/molmil-images/mine/7kfq) | Crystal structure of the MarR family transcriptional regulator from Variovorax paradoxus bound to 1H-Indole-3-Carboxylic Acid | 分子名称: | 1H-INDOLE-3-CARBOXYLIC ACID, SULFATE ION, Transcriptional regulator, ... | 著者 | Walton, W.G, Redinbo, M.R, Dangl, J.L. | 登録日 | 2020-10-14 | 公開日 | 2021-11-10 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Diverse MarR bacterial regulators of auxin catabolism in the plant microbiome. Nat Microbiol, 7, 2022
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8Q1X
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![BU of 8q1x by Molmil](/molmil-images/mine/8q1x) | Structural analysis of PLD3 reveals insights into the mechanism of lysosomal 5' exonuclease-mediated nucleic acid degradation | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5'-3' exonuclease PLD3, ... | 著者 | Roske, Y, Daumke, O, Damme, M. | 登録日 | 2023-08-01 | 公開日 | 2023-12-06 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structural analysis of PLD3 reveals insights into the mechanism of lysosomal 5' exonuclease-mediated nucleic acid degradation. Nucleic Acids Res., 52, 2024
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7KFO
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![BU of 7kfo by Molmil](/molmil-images/mine/7kfo) | Crystal structure of the MarR family transcriptional regulator from Variovorax paradoxus bound to Indole 3 acetic acid | 分子名称: | 1H-INDOL-3-YLACETIC ACID, SULFATE ION, Transcriptional regulator, ... | 著者 | Walton, W.G, Redinbo, M.R, Dangl, J.L. | 登録日 | 2020-10-14 | 公開日 | 2021-11-10 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Diverse MarR bacterial regulators of auxin catabolism in the plant microbiome. Nat Microbiol, 7, 2022
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7QCO
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![BU of 7qco by Molmil](/molmil-images/mine/7qco) | The structure of Photosystem I tetramer from Chroococcidiopsis TS-821, a thermophilic, unicellular, non-heterocyst-forming cyanobacterium | 分子名称: | 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, BETA-CAROTENE, CHLOROPHYLL A, ... | 著者 | Semchonok, D.A, Mondal, J, Cooper, J.C, Schlum, K, Li, M, Amin, M, Sorzano, C.O.S, Ramirez-Aportela, E, Kastritis, P.L, Boekema, E.J, Guskov, A, Bruce, B.D. | 登録日 | 2021-11-24 | 公開日 | 2022-04-06 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Cryo-EM structure of a tetrameric photosystem I from Chroococcidiopsis TS-821, a thermophilic, unicellular, non-heterocyst-forming cyanobacterium. Plant Commun., 3, 2022
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7SWW
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![BU of 7sww by Molmil](/molmil-images/mine/7sww) | |