7AZ4

Perdeuterated E65Q-TIM complexed with 2-PHOSPHOGLYCOLIC ACID

Summary for 7AZ4

Entry DOI	10.2210/pdb7az4/pdb
Descriptor	Triosephosphate isomerase, 2-PHOSPHOGLYCOLIC ACID (3 entities in total)
Functional Keywords	isomerase, glycolysis, tim, triosephosphate isomerase, transition state, perdeuteration
Biological source	Leishmania mexicana
Total number of polymer chains	1
Total formula weight	27364.27
Authors	Kelpsas, V.,Caldararu, O.,von Wachenfeldt, C.,Oksanen, E. (deposition date: 2020-11-16, release date: 2021-07-28)
Primary citation	Kelpsas, V.,Caldararu, O.,Blakeley, M.P.,Coquelle, N.,Wierenga, R.K.,Ryde, U.,von Wachenfeldt, C.,Oksanen, E. Neutron structures of Leishmania mexicana triosephosphate isomerase in complex with reaction-intermediate mimics shed light on the proton-shuttling steps. Iucrj, 8:633-643, 2021 Cited by PubMed: 34258011 DOI: 10.1107/S2052252521004619 PDB entries with the same primary citation
Experimental method	NEUTRON DIFFRACTION (1.7 Å) X-RAY DIFFRACTION (1.15 Å)

Structure validation