7D5S
 
 | | Cryo-EM structure of 90S preribosome with inactive Utp24 (state A2) | | 分子名称: | 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S12, ... | | 著者 | Du, Y, Zhang, J, An, W, Ye, K. | | 登録日 | 2020-09-28 | | 公開日 | 2021-10-06 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | | 主引用文献 | Cryo-EM structure of 90S preribosome with inactive Utp24 (state A2)
To Be Published
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4DTJ
 | | RB69 DNA Polymerase Ternary Complex with dTTP Opposite an Abasic Site and ddT/dA as the Penultimate Base-pair | | 分子名称: | CALCIUM ION, DNA polymerase, DNA primer, ... | | 著者 | Xia, S, Wang, J, Konigsberg, W.H. | | 登録日 | 2012-02-21 | | 公開日 | 2012-06-06 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Contribution of Partial Charge Interactions and Base Stacking to the Efficiency of Primer Extension at and beyond Abasic Sites in DNA.
Biochemistry, 51, 2012
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5LKS
 | | Structure-function insights reveal the human ribosome as a cancer target for antibiotics | | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ... | | 著者 | Myasnikov, A.G, Natchiar, S.K, Nebout, M, Hazemann, I, Imbert, V, Khatter, H, Peyron, J.-F, Klaholz, B.P. | | 登録日 | 2016-07-23 | | 公開日 | 2017-04-26 | | 最終更新日 | 2019-12-11 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structure-function insights reveal the human ribosome as a cancer target for antibiotics.
Nat Commun, 7, 2016
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4WA6
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4W4U
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3EED
 | | Crystal structure of human protein kinase CK2 regulatory subunit (CK2beta; mutant 1-193) | | 分子名称: | Casein kinase II subunit beta, SULFATE ION, ZINC ION | | 著者 | Niefind, K, Raaf, J, Issinger, O.-G. | | 登録日 | 2008-09-04 | | 公開日 | 2008-09-16 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | The interaction of CK2{alpha} and CK2{beta}, the subunits of protein kinase CK2, requires CK2{beta} in a preformed conformation and is enthalpically driven
Protein Sci., 17, 2008
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7D5T
 | | Cryo-EM structure of 90S preribosome with inactive Utp24 (state F1) | | 分子名称: | 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ... | | 著者 | Du, Y, Zhang, J, An, W, Ye, K. | | 登録日 | 2020-09-28 | | 公開日 | 2021-10-06 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (6 Å) | | 主引用文献 | Cryo-EM structure of 90S preribosome with inactive Utp24 (state F1)
To Be Published
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8SCB
 | | Terminating ribosome with SRI-41315 | | 分子名称: | (2S,4aS)-2-cyclobutyl-10-methyl-3-phenyl-2,10-dihydropyrimido[4,5-b]quinoline-4,5(3H,4aH)-dione, 18S_rRNA, 28S_rRNA, ... | | 著者 | Yip, M.C.J, Coelho, J.P.L, Oltion, K, Tauton, J, Shao, S. | | 登録日 | 2023-04-05 | | 公開日 | 2023-12-27 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | The eRF1 degrader SRI-41315 acts as a molecular glue at the ribosomal decoding center.
Nat.Chem.Biol., 20, 2024
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7QWS
 | | Structure of ribosome translating beta-tubulin in complex with TTC5 and NAC | | 分子名称: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | | 著者 | Jomaa, A, Gamerdinger, M, Hsieh, H, Wallisch, A, Chandrasekaran, V, Ulusoy, Z, Scaiola, A, Hegde, R, Shan, S, Ban, N, Deuerling, E. | | 登録日 | 2022-01-25 | | 公開日 | 2022-03-09 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Mechanism of signal sequence handover from NAC to SRP on ribosomes during ER-protein targeting.
Science, 375, 2022
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8G88
 | | Human Oct4 bound to nucleosome with human nMatn1 sequence | | 分子名称: | Histone H2A, Histone H2B, Histone H3, ... | | 著者 | Sinha, K.K, Bilokapic, S, Du, Y, Malik, D, Halic, M. | | 登録日 | 2023-02-17 | | 公開日 | 2023-03-22 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | | 主引用文献 | Histone modifications regulate pioneer transcription factor cooperativity.
Nature, 619, 2023
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8G8B
 | | Nucleosome with human nMatn1 sequence in complex with Human Oct4 | | 分子名称: | Histone H2A, Histone H2B, Histone H3, ... | | 著者 | Sinha, K.K, Bilokapic, S, Du, Y, Malik, D, Halic, M. | | 登録日 | 2023-02-17 | | 公開日 | 2023-03-22 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Histone modifications regulate pioneer transcription factor cooperativity.
Nature, 619, 2023
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8G8G
 | | Interaction of H3 tail in LIN28B nucleosome with Oct4 | | 分子名称: | Histone H2A, Histone H2B, Histone H3, ... | | 著者 | Sinha, K.K, Bilokapic, S, Du, Y, Malik, D, Halic, M. | | 登録日 | 2023-02-17 | | 公開日 | 2023-03-22 | | 最終更新日 | 2023-12-13 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Histone modifications regulate pioneer transcription factor cooperativity.
Nature, 619, 2023
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8FON
 | | Crystal structure of tRNA^Lys(SUU) bound to AUA codon in the ribosomal P site | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | 著者 | Nguyen, H.A, Hoffer, E.D, Maehigashi, T, Fagan, C.E, Dunham, C.M. | | 登録日 | 2023-01-02 | | 公開日 | 2023-03-29 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (3.64 Å) | | 主引用文献 | Structural basis for reduced ribosomal A-site fidelity in response to P-site codon-anticodon mismatches.
J.Biol.Chem., 299, 2023
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7WTW
 | | Cryo-EM structure of a human pre-40S ribosomal subunit - State RRP12-A3 | | 分子名称: | 18S rRNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ... | | 著者 | Cheng, J, Lau, B, Thoms, M, Ameismeier, M, Berninghausen, O, Hurt, E, Beckmann, R. | | 登録日 | 2022-02-05 | | 公開日 | 2022-10-19 | | 最終更新日 | 2024-06-26 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | The nucleoplasmic phase of pre-40S formation prior to nuclear export.
Nucleic Acids Res., 50, 2022
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4ZUX
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5OOB
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6SWA
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8FOM
 | | Crystal structure of tRNA^Lys(SUU) bound to UAA codon in the ribosomal P site | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | 著者 | Nguyen, H.A, Hoffer, E.D, Maehigashi, T, Fagan, C.E, Dunham, C.M. | | 登録日 | 2023-01-02 | | 公開日 | 2023-03-29 | | 最終更新日 | 2023-04-26 | | 実験手法 | X-RAY DIFFRACTION (3.58 Å) | | 主引用文献 | Structural basis for reduced ribosomal A-site fidelity in response to P-site codon-anticodon mismatches.
J.Biol.Chem., 299, 2023
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8RJB
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8R3V
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7WTT
 | | Cryo-EM structure of a human pre-40S ribosomal subunit - State RRP12-A1 (with CK1) | | 分子名称: | 18S rRNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ... | | 著者 | Cheng, J, Lau, B, Thoms, M, Ameismeier, M, Berninghausen, O, Hurt, E, Beckmann, R. | | 登録日 | 2022-02-05 | | 公開日 | 2022-10-19 | | 最終更新日 | 2024-06-26 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | The nucleoplasmic phase of pre-40S formation prior to nuclear export.
Nucleic Acids Res., 50, 2022
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7PLO
 | | H. sapiens replisome-CUL2/LRR1 complex | | 分子名称: | Cell division control protein 45 homolog, Claspin, Cullin-2, ... | | 著者 | Jones, M.J, Yeeles, J.T.P, Deegan, T.D, Jenkyn-Bedford, M. | | 登録日 | 2021-09-01 | | 公開日 | 2021-11-10 | | 最終更新日 | 2023-10-18 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | A conserved mechanism for regulating replisome disassembly in eukaryotes.
Nature, 600, 2021
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8RCM
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8RCS
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8RCT
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