7EKO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7eko by Molmil](/molmil-images/mine/7eko) | CrClpP-S1 | 分子名称: | ATP-dependent Clp protease ATP-binding subunit CLPT4, chloroplastic, ATP-dependent Clp protease proteolytic subunit | 著者 | Wang, N, Wang, Y.F, Cong, Y, Liu, C.M. | 登録日 | 2021-04-06 | 公開日 | 2021-10-20 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | The cryo-EM structure of the chloroplast ClpP complex. Nat.Plants, 7, 2021
|
|
2Z9J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2z9j by Molmil](/molmil-images/mine/2z9j) | |
7E8E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7e8e by Molmil](/molmil-images/mine/7e8e) | |
7AXB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7axb by Molmil](/molmil-images/mine/7axb) | Crystal structure of the hPXR-LBD in complex with endosulfan | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, GLYCEROL, Nuclear receptor subfamily 1 group I member 2, ... | 著者 | Huet, T, Delfosse, V, Bourguet, W. | 登録日 | 2020-11-09 | 公開日 | 2021-01-13 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Mechanistic insights into the synergistic activation of the RXR-PXR heterodimer by endocrine disruptor mixtures. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
7AXG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7axg by Molmil](/molmil-images/mine/7axg) | Crystal structure of the hPXR-LBD in complex with tributyltin | 分子名称: | Nuclear receptor subfamily 1 group I member 2, tributylstannanyl | 著者 | Delfosse, V, Huet, T, Blanc, P, Bourguet, W. | 登録日 | 2020-11-09 | 公開日 | 2021-01-13 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Mechanistic insights into the synergistic activation of the RXR-PXR heterodimer by endocrine disruptor mixtures. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
7PH8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ph8 by Molmil](/molmil-images/mine/7ph8) | |
5L5G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5l5g by Molmil](/molmil-images/mine/5l5g) | Plexin A2 full extracellular region, domains 1 to 8 modeled, data to 10 angstrom | 分子名称: | Plexin-A2 | 著者 | Janssen, B.J.C, Kong, Y, Malinauskas, T, Vangoor, V.R, Coles, C.H, Kaufmann, R, Ni, T, Gilbert, R.J.C, Padilla-Parra, S, Pasterkamp, R.J, Jones, E.Y. | 登録日 | 2016-05-28 | 公開日 | 2016-07-06 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (10 Å) | 主引用文献 | Structural Basis for Plexin Activation and Regulation. Neuron, 91, 2016
|
|
2ZRS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2zrs by Molmil](/molmil-images/mine/2zrs) | Crystal structure of Ca2+-bound form of des3-23ALG-2 | 分子名称: | CALCIUM ION, Programmed cell death protein 6 | 著者 | Suzuki, H, Kawasaki, M, Kakiuchi, T, Shibata, H, Wakatsuki, S, Maki, M. | 登録日 | 2008-09-01 | 公開日 | 2008-11-04 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Crystallization and X-ray diffraction analysis of N-terminally truncated human ALG-2 ACTA CRYSTALLOGR.,SECT.F, 64, 2008
|
|
2ZAV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2zav by Molmil](/molmil-images/mine/2zav) | |
7K9T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7k9t by Molmil](/molmil-images/mine/7k9t) | Co-crystal structure of alpha glucosidase with compound 5 | 分子名称: | (1S,2S,3R,4S,5S)-1-(hydroxymethyl)-5-{[(5Z)-6-{[2-nitro-4-(2H-1,2,3-triazol-2-yl)phenyl]amino}hex-5-en-1-yl]amino}cyclohexane-1,2,3,4-tetrol, 1,2-ETHANEDIOL, Alpha glucosidase 2 alpha neutral subunit, ... | 著者 | Karade, S.S, Mariuzza, R.A. | 登録日 | 2020-09-29 | 公開日 | 2021-09-29 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | N-Substituted Valiolamine Derivatives as Potent Inhibitors of Endoplasmic Reticulum alpha-Glucosidases I and II with Antiviral Activity. J.Med.Chem., 64, 2021
|
|
7PXL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7pxl by Molmil](/molmil-images/mine/7pxl) | X-ray structure of LPMO at 3.6x10^5 Gy | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Auxiliary activity 9, CHLORIDE ION, ... | 著者 | Tandrup, T, Lo Leggio, L. | 登録日 | 2021-10-08 | 公開日 | 2022-08-24 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Changes in active-site geometry on X-ray photoreduction of a lytic polysaccharide monooxygenase active-site copper and saccharide binding. Iucrj, 9, 2022
|
|
3HXD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3hxd by Molmil](/molmil-images/mine/3hxd) | Engineered RabGGTase in complex with a peptidomimetic inhibitor (compound 9) | 分子名称: | CALCIUM ION, Geranylgeranyl transferase type-2 subunit alpha, Geranylgeranyl transferase type-2 subunit beta, ... | 著者 | Guo, Z, Alexandrov, K, Waldmann, H, Goody, R.S, Blankenfeldt, W. | 登録日 | 2009-06-20 | 公開日 | 2009-09-08 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Design, synthesis, and characterization of Peptide-based rab geranylgeranyl transferase inhibitors J.Med.Chem., 52, 2009
|
|
7PXS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7pxs by Molmil](/molmil-images/mine/7pxs) | Room temperature X-ray structure of LPMO at 1.91x10^3 Gy | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Auxiliary activity 9, COPPER (II) ION | 著者 | Tandrup, T, Muderspach, S.J, Banerjee, S, Lo Leggio, L. | 登録日 | 2021-10-08 | 公開日 | 2022-08-24 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Changes in active-site geometry on X-ray photoreduction of a lytic polysaccharide monooxygenase active-site copper and saccharide binding. Iucrj, 9, 2022
|
|
7K9Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7k9q by Molmil](/molmil-images/mine/7k9q) | Co-crystal structure of alpha glucosidase with compound 4 | 分子名称: | (1S,2S,3R,4S,5S)-5-amino-1-(hydroxymethyl)cyclohexane-1,2,3,4-tetrol, 1,2-ETHANEDIOL, Alpha glucosidase 2 alpha neutral subunit, ... | 著者 | Karade, S.S, Mariuzza, R.A. | 登録日 | 2020-09-29 | 公開日 | 2021-09-29 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | N-Substituted Valiolamine Derivatives as Potent Inhibitors of Endoplasmic Reticulum alpha-Glucosidases I and II with Antiviral Activity. J.Med.Chem., 64, 2021
|
|
7B0S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7b0s by Molmil](/molmil-images/mine/7b0s) | TRPC4 in complex with inhibitor GFB-8438 | 分子名称: | (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, 5-chloranyl-4-[3-oxidanylidene-4-[[2-(trifluoromethyl)phenyl]methyl]piperazin-1-yl]-1~{H}-pyridazin-6-one, CALCIUM ION, ... | 著者 | Vinayagam, D, Quentin, D, Sistel, O, Merino, F, Stabrin, M, Hofnagel, O, Ledeboer, M.W, Malojcic, G, Raunser, S. | 登録日 | 2020-11-21 | 公開日 | 2020-12-09 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structural basis of TRPC4 regulation by calmodulin and pharmacological agents. Elife, 9, 2020
|
|
2MKR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2mkr by Molmil](/molmil-images/mine/2mkr) | Structural Characterization of a Complex Between the Acidic Transactivation Domain of EBNA2 and the Tfb1/p62 subunit of TFIIH. | 分子名称: | Epstein-Barr nuclear antigen 2, RNA polymerase II transcription factor B subunit 1 | 著者 | Chabot, P.R, Raiola, L, Lussier-Price, M, Morse, T, Arseneault, G, Archambault, J, Omichinski, J. | 登録日 | 2014-02-12 | 公開日 | 2014-03-05 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural and Functional Characterization of a Complex between the Acidic Transactivation Domain of EBNA2 and the Tfb1/p62 Subunit of TFIIH. Plos Pathog., 10, 2014
|
|
7E1X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7e1x by Molmil](/molmil-images/mine/7e1x) | Cryo-EM structure of hybrid respiratory supercomplex consisting of Mycobacterium tuberculosis complexIII and Mycobacterium smegmatis complexIV in presence of TB47 | 分子名称: | (2R)-2-(hexadecanoyloxy)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl (9S)-9-methyloctadecanoate, (2R)-3-(((2-aminoethoxy)(hydroxy)phosphoryl)oxy)-2-(palmitoyloxy)propyl (E)-octadec-9-enoate, 5-methoxy-2-methyl-~{N}-[[4-[4-[4-(trifluoromethyloxy)phenyl]piperidin-1-yl]phenyl]methyl]pyrazolo[1,5-a]pyridine-3-carboxamide, ... | 著者 | Zhou, S, Wang, W, Gao, Y, Gong, H, Rao, Z. | 登録日 | 2021-02-03 | 公開日 | 2021-10-27 | 最終更新日 | 2022-07-27 | 実験手法 | ELECTRON MICROSCOPY (2.93 Å) | 主引用文献 | Structure of Mycobacterium tuberculosis cytochrome bcc in complex with Q203 and TB47, two anti-TB drug candidates. Elife, 10, 2021
|
|
2MNY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2mny by Molmil](/molmil-images/mine/2mny) | NMR Structure of KDM5B PHD1 finger | 分子名称: | Lysine-specific demethylase 5B, ZINC ION | 著者 | Zhang, Y, Yang, H.R, Guo, X, Rong, N.Y, Song, Y.J, Xu, Y.W, Lan, W.X, Xu, Y.H, Cao, C. | 登録日 | 2014-04-16 | 公開日 | 2014-08-06 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | The PHD1 finger of KDM5B recognizes unmodified H3K4 during the demethylation of histone H3K4me2/3 by KDM5B. Protein Cell, 5, 2014
|
|
7AHZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ahz by Molmil](/molmil-images/mine/7ahz) | |
8P1F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8p1f by Molmil](/molmil-images/mine/8p1f) | X-ray structure of acetylcholine-binding protein (AChBP) in complex with FL001909. | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-azanyl-1-phenyl-piperidine-4-carboxylic acid, Acetylcholine-binding protein | 著者 | Cederfelt, D, Boronat, P, Dobritzsch, D, Hennig, S, Fitzgerald, E.A, de Esch, I.J.P, Danielson, U.H. | 登録日 | 2023-05-12 | 公開日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Elucidating the regulation of ligand gated ion channels via biophysical studies of ligand-induced conformational dynamics of acetylcholine binding proteins To Be Published
|
|
7E1W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7e1w by Molmil](/molmil-images/mine/7e1w) | Cryo-EM structure of hybrid respiratory supercomplex consisting of Mycobacterium tuberculosis complexIII and Mycobacterium smegmatis complexIV in the presence of Q203 | 分子名称: | (2R)-2-(hexadecanoyloxy)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl (9S)-9-methyloctadecanoate, (2R)-3-(((2-aminoethoxy)(hydroxy)phosphoryl)oxy)-2-(palmitoyloxy)propyl (E)-octadec-9-enoate, 6-chloranyl-2-ethyl-N-[[4-[4-[4-(trifluoromethyloxy)phenyl]piperidin-1-yl]phenyl]methyl]imidazo[1,2-a]pyridine-3-carboxamide, ... | 著者 | Zhou, S, Wang, W, Gao, Y, Gong, H, Rao, Z. | 登録日 | 2021-02-03 | 公開日 | 2021-10-27 | 最終更新日 | 2022-07-27 | 実験手法 | ELECTRON MICROSCOPY (2.67 Å) | 主引用文献 | Structure of Mycobacterium tuberculosis cytochrome bcc in complex with Q203 and TB47, two anti-TB drug candidates. Elife, 10, 2021
|
|
2ZT6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2zt6 by Molmil](/molmil-images/mine/2zt6) | |
7EG1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7eg1 by Molmil](/molmil-images/mine/7eg1) | Cryo-EM structure of DNMDP-induced PDE3A-SLFN12 complex | 分子名称: | (4~{R})-3-[4-(diethylamino)-3-[oxidanyl(oxidanylidene)-$l^{4}-azanyl]phenyl]-4-methyl-4,5-dihydro-1~{H}-pyridazin-6-one, MAGNESIUM ION, Schlafen family member 12, ... | 著者 | Liu, N, Chen, J, Wang, X.D, Wang, H.W. | 登録日 | 2021-03-23 | 公開日 | 2021-11-03 | 最終更新日 | 2022-05-25 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structure of PDE3A-SLFN12 complex and structure-based design for a potent apoptosis inducer of tumor cells. Nat Commun, 12, 2021
|
|
7Q5N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7q5n by Molmil](/molmil-images/mine/7q5n) | Crystal structure of Chaetomium thermophilum Ahp1-Urm1 complex | 分子名称: | Thioredoxin domain-containing protein, Ubiquitin-related modifier 1, ZINC ION | 著者 | Ravichandran, K.E, Wilk, P, Grudnik, P, Glatt, S. | 登録日 | 2021-11-04 | 公開日 | 2022-08-24 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | E2/E3-independent ubiquitin-like protein conjugation by Urm1 is directly coupled to cysteine persulfidation. Embo J., 41, 2022
|
|
7E8B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7e8b by Molmil](/molmil-images/mine/7e8b) | CryoEM structure of human Kv4.2-DPP6S complex | 分子名称: | Dipeptidyl aminopeptidase-like protein 6, Potassium voltage-gated channel subfamily D member 2 | 著者 | Kise, Y, Nureki, O. | 登録日 | 2021-03-01 | 公開日 | 2021-10-13 | 最終更新日 | 2022-02-16 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Structural basis of gating modulation of Kv4 channel complexes. Nature, 599, 2021
|
|