2ZT6
Crystal structure of human Glycyl-tRNA synthetase (GlyRS) in complex with AMPCPP
Summary for 2ZT6
Entry DOI | 10.2210/pdb2zt6/pdb |
Related | 2PME 2PMF 2ZT5 2ZT7 2ZT8 |
Descriptor | Glycyl-tRNA synthetase, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER (3 entities in total) |
Functional Keywords | ligase, ap4a, glycine, atp, gly-amp, trna, aminoacyl-trna synthetase, atp-binding, charcot-marie-tooth disease, disease mutation, nucleotide-binding, phosphoprotein, protein biosynthesis |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm: P41250 |
Total number of polymer chains | 1 |
Total formula weight | 79210.04 |
Authors | Guo, R.T.,Yang, X.L.,Schimmel, P. (deposition date: 2008-09-19, release date: 2009-08-25, Last modification date: 2023-11-01) |
Primary citation | Guo, R.T.,Chong, Y.E.,Guo, M.,Yang, X.L. Crystal structures and biochemical analyses suggest unique mechanism and role for human GlyRS in Ap4A homeostasis To be Published, |
Experimental method | X-RAY DIFFRACTION (3.08 Å) |
Structure validation
Download full validation report