7E1X

Cryo-EM structure of hybrid respiratory supercomplex consisting of Mycobacterium tuberculosis complexIII and Mycobacterium smegmatis complexIV in presence of TB47

Summary for 7E1X

• Entry DOI: 10.2210/pdb7e1x/pdb
• EMDB information: 30943 30944 30945
• Descriptor: Cytochrome c oxidase subunit 2, Cytochrome bc1 complex cytochrome c subunit, COPPER (II) ION, ... (21 entities in total)
• Functional Keywords: mycobacterium smegmatis, mycobacterium tuberculosis, complexiii, complexiv, electron transport, anti-tb drugs, oxidoreductase
• Biological source: Mycobacterium tuberculosis H37Rv; More
• Total number of polymer chains: 20
• Total formula weight: 672187.28

Authors

Zhou, S.,Wang, W.,Gao, Y.,Gong, H.,Rao, Z. (deposition date: 2021-02-03, release date: 2021-10-27, Last modification date: 2022-07-27)

• Primary citation: Zhou, S.,Wang, W.,Zhou, X.,Zhang, Y.,Lai, Y.,Tang, Y.,Xu, J.,Li, D.,Lin, J.,Yang, X.,Ran, T.,Chen, H.,Guddat, L.W.,Wang, Q.,Gao, Y.,Rao, Z.,Gong, H.; Structure of Mycobacterium tuberculosis cytochrome bcc in complex with Q203 and TB47, two anti-TB drug candidates.; Elife, 10:-, 2021; PubMed: 34819223; DOI: 10.7554/eLife.69418

Experimental method

ELECTRON MICROSCOPY (2.93 Å)