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2AB4
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Dissecting the Roles of a Strictly Conserved Tyrosine in Substrate Recognition and Catalysis by Pseudouridine 55 Synthase
分子名称: 5'-R(*CP*CP*AP*CP*GP*GP*UP*(FHU)P*CP*GP*AP*AP*UP*CP*CP*GP*UP*GP*GP*C)-3', ZINC ION, tRNA pseudouridine synthase B
著者Phannachet, K, Elias, Y, Huang, R.H.
登録日2005-07-14
公開日2005-12-13
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Dissecting the roles of a strictly conserved tyrosine in substrate recognition and catalysis by pseudouridine 55 synthase.
Biochemistry, 44, 2005
2AB5
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bI3 LAGLIDADG Maturase
分子名称: SULFATE ION, mRNA maturase
著者Longo, A, Leonard, C.W, Bassi, G.S, Berndt, D, Krahn, J.M, Hall, T.M, Weeks, K.M.
登録日2005-07-14
公開日2005-08-30
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Evolution from DNA to RNA recognition by the bI3 LAGLIDADG maturase
Nat.Struct.Mol.Biol., 12, 2005
2AB6
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HUMAN GLUTATHIONE S-TRANSFERASE M2-2 (E.C.2.5.1.18) complexed with S-METHYLGLUTATHIONE
分子名称: Glutathione S-transferase Mu 2, L-GAMMA-GLUTAMYL-S-METHYLCYSTEINYLGLYCINE
著者Patskovsky, Y, Almo, S.C, Listowsky, I.
登録日2005-07-14
公開日2005-08-02
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Perturbations in the Active Site of Human Glutathione-S-Transferase M2-2 Upon Ligand Binding
To be Published
2AB7
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Solution structures and characterization of HIV RRE IIB RNA targeting zinc finger proteins
分子名称: ZINC ION, ZNF29G29R
著者Mishra, S.H, Shelley, C.M, Darby, M.K, Germann, M.W.
登録日2005-07-14
公開日2005-08-02
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structures and characterization of human immunodeficiency virus Rev responsive element IIB RNA targeting zinc finger proteins.
Biopolymers, 83, 2006
2AB8
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Crystal structure of T. gondii adenosine kinase complexed with 6-methylmercaptopurine riboside and AMP-PCP
分子名称: 2-HYDROXYMETHYL-5-(6-METHYLSULFANYL-PURIN-9-YL)-TETRAHYDRO-FURAN-3,4-DIOL, CHLORIDE ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ...
著者Zhang, Y, el Kouni, M.H, Ealick, S.E.
登録日2005-07-14
公開日2006-07-25
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Substrate analogs induce an intermediate conformational change in Toxoplasma gondii adenosine kinase
Acta Crystallogr.,Sect.D, 63, 2007
2AB9
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Discovery, structural determination and processing of the precursor protein that produces the cyclic trypsin inhibitor SFTI-1
分子名称: pro-SFTI-1
著者Mulvenna, J.P, Foley, F.M, Craik, D.J.
登録日2005-07-15
公開日2005-07-26
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献Discovery, structural determination and putative processing of the precursor protein that produces the cyclic trypsin inhibitor SFTI-1
J.Biol.Chem., 280, 2005
2ABA
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Structure of reduced PETN reductase in complex with progesterone
分子名称: FLAVIN MONONUCLEOTIDE, ISOPROPYL ALCOHOL, PROGESTERONE, ...
著者Khan, H, Barna, T, Bruce, N.C, Munro, A.W, Leys, D, Scrutton, N.S.
登録日2005-07-15
公開日2005-10-11
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献Proton transfer in the oxidative half-reaction of pentaerythritol tetranitrate reductase
Febs J., 272, 2005
2ABB
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Structure of PETN reductase Y186F in complex with cyanide
分子名称: FLAVIN MONONUCLEOTIDE, ISOPROPYL ALCOHOL, THIOCYANATE ION, ...
著者Khan, H, Barna, T, Bruce, N.C, Munro, A.W, Leys, D, Scrutton, N.S.
登録日2005-07-15
公開日2005-10-11
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Proton transfer in the oxidative half-reaction of pentaerythritol tetranitrate reductase
Febs J., 272, 2005
2ABD
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THE THREE-DIMENSIONAL STRUCTURE OF ACYL-COENZYME A BINDING PROTEIN FROM BOVINE LIVER. STRUCTURAL REFINEMENT USING HETERONUCLEAR MULTIDIMENSIONAL NMR SPECTROSCOPY
分子名称: ACYL-COENZYME A BINDING PROTEIN
著者Andersen, K.V, Poulsen, F.M.
登録日1993-03-05
公開日1993-07-15
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献The three-dimensional structure of acyl-coenzyme A binding protein from bovine liver: structural refinement using heteronuclear multidimensional NMR spectroscopy.
J.Biomol.NMR, 3, 1993
2ABE
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Carbonic anhydrase activators: X-ray crystal structure of the adduct of human isozyme II with L-histidine as a platform for the design of stronger activators
分子名称: Carbonic anhydrase II, HISTIDINE, MERCURY (II) ION, ...
著者Temperini, C, Scozzafava, A, Puccetti, L, Supuran, C.T.
登録日2005-07-15
公開日2005-10-25
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Carbonic anhydrase activators: X-ray crystal structure of the adduct of human isozyme II with l-histidine as a platform for the design of stronger activators.
Bioorg.Med.Chem.Lett., 15, 2005
2ABH
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PHOSPHATE-BINDING PROTEIN (RE-REFINED)
分子名称: PHOSPHATE ION, PHOSPHATE-BINDING PROTEIN
著者Yao, N, Choudhary, A, Ledvina, P.S, Quiocho, F.A.
登録日1995-11-28
公開日1997-04-21
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Modulation of a salt link does not affect binding of phosphate to its specific active transport receptor.
Biochemistry, 35, 1996
2ABI
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Crystal structure of the human mineralocorticoid receptor ligand-binding domain bound to deoxycorticosterone
分子名称: DESOXYCORTICOSTERONE, Mineralocorticoid receptor
著者Huyet, J, Pinon, G.-M, Rochel, M, Mayer, C, Rafestin-Oblin, M.-E, Fagart, J.
登録日2005-07-15
公開日2006-07-25
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Crystal structure of the human mineralocorticoid receptor ligand-binding domain bound to deoxycorticosterone
To be published
2ABJ
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Crystal structure of human branched chain amino acid transaminase in a complex with an inhibitor, C16H10N2O4F3SCl, and pyridoxal 5' phosphate.
分子名称: Branched-chain-amino-acid aminotransferase, cytosolic, N'-(5-CHLOROBENZOFURAN-2-CARBONYL)-2-(TRIFLUOROMETHYL)BENZENESULFONOHYDRAZIDE, ...
著者Ohren, J.F, Moreland, D.W, Rubin, J.R, Hu, H.L, McConnell, P.C, Mistry, A, Mueller, W.T, Scholten, J.D, Hasemann, C.H.
登録日2005-07-15
公開日2006-06-27
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The design and synthesis of human branched-chain amino acid aminotransferase inhibitors for treatment of neurodegenerative diseases.
Bioorg.Med.Chem.Lett., 16, 2006
2ABK
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REFINEMENT OF THE NATIVE STRUCTURE OF ENDONUCLEASE III TO A RESOLUTION OF 1.85 ANGSTROM
分子名称: ENDONUCLEASE III, IRON/SULFUR CLUSTER
著者Thayer, M.M, Tainer, J.A.
登録日1995-05-11
公開日1995-10-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Novel DNA binding motifs in the DNA repair enzyme endonuclease III crystal structure.
EMBO J., 14, 1995
2ABL
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SH3-SH2 DOMAIN FRAGMENT OF HUMAN BCR-ABL TYROSINE KINASE
分子名称: ABL TYROSINE KINASE
著者Nam, H.-J, Frederick, C.A.
登録日1996-11-17
公開日1997-09-04
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Intramolecular interactions of the regulatory domains of the Bcr-Abl kinase reveal a novel control mechanism.
Structure, 4, 1996
2ABM
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Crystal Structure of Aquaporin Z Tetramer Reveals both Open and Closed Water-conducting Channels
分子名称: (1S)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PENTANOYLOXY)METHYL]ETHYL OCTANOATE, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 2-O-octyl-beta-D-glucopyranose, ...
著者Jiang, J, Daniels, B.V, Fu, D.
登録日2005-07-15
公開日2005-09-20
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal Structure of AqpZ Tetramer Reveals Two Distinct Arg-189 Conformations Associated with Water Permeation through the Narrowest Constriction of the Water-conducting Channel.
J.Biol.Chem., 281, 2006
2ABO
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NMR structure of gamma herpesvirus 68 a viral Bcl-2 homolog
分子名称: bcl-2 homolog
著者Loh, J, Huang, Q, Petros, A.M, Nettesheim, D, van Dyk, L.F, Labrada, L, Speck, S.H, Levine, B, Olejniczak, E.T, Virgin, H.W.
登録日2005-07-15
公開日2006-05-16
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献A surface groove essential for viral Bcl-2 function during chronic infection in vivo.
Plos Pathog., 1, 2005
2ABQ
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Crystal structure of fructose-1-phosphate kinase from Bacillus halodurans
分子名称: PHOSPHATE ION, fructose 1-phosphate kinase
著者Eswaramoorthy, S, Swaminathan, S, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2005-07-15
公開日2005-08-02
最終更新日2021-02-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of fructose-1-phosphate kinase from Bacillus halodurans
To be Published
2ABR
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Structure of D280A arginine deiminase with L-arginine forming a S-alkylthiouronium reaction intermediate
分子名称: Arginine deiminase
著者Galkin, A, Lu, X, Dunaway-Mariano, D, Herzberg, O.
登録日2005-07-15
公開日2005-08-09
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal Structures Representing the Michaelis Complex and the Thiouronium Reaction Intermediate of Pseudomonas aeruginosa Arginine Deiminase.
J.Biol.Chem., 280, 2005
2ABS
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Crystal structure of T. gondii adenosine kinase complexed with AMP-PCP
分子名称: CHLORIDE ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, SODIUM ION, ...
著者Zhang, Y, el Kouni, M.H, Ealick, S.E.
登録日2005-07-16
公開日2006-01-24
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Structure of Toxoplasma gondii adenosine kinase in complex with an ATP analog at 1.1 angstroms resolution.
Acta Crystallogr.,Sect.D, 62, 2006
2ABW
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Glutaminase subunit of the plasmodial PLP synthase (Vitamin B6 biosynthesis)
分子名称: Pdx2 protein, TETRAETHYLENE GLYCOL
著者Gengenbacher, M, Fitzpatrick, T.B, Raschle, T, Flicker, K, Sinning, I, Mueller, S, Macheroux, P, Tews, I, Kappes, B.
登録日2005-07-17
公開日2006-01-10
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Vitamin B6 Biosynthesis by the Malaria Parasite Plasmodium falciparum: Biochemical and structural insights
J.Biol.Chem., 281, 2006
2ABX
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THE CRYSTAL STRUCTURE OF ALPHA-BUNGAROTOXIN AT 2.5 ANGSTROMS RESOLUTION. RELATION TO SOLUTION STRUCTURE AND BINDING TO ACETYLCHOLINE RECEPTOR
分子名称: ALPHA-BUNGAROTOXIN
著者Love, R, Stroud, R.
登録日1986-02-19
公開日1986-05-07
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The crystal structure of alpha-bungarotoxin at 2.5 A resolution: relation to solution structure and binding to acetylcholine receptor.
Protein Eng., 1, 1986
2ABY
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Solution structure of TA0743 from Thermoplasma acidophilum
分子名称: hypothetical protein TA0743
著者Kim, B, Jung, J, Hong, E, Yee, A, Arrowsmith, C.H, Lee, W.
登録日2005-07-18
公開日2006-08-08
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献NMR structure of the conserved novel-fold protein TA0743 from Thermoplasma acidophilum.
Proteins, 62, 2006
2ABZ
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Crystal structure of C19A/C43A mutant of leech carboxypeptidase inhibitor in complex with bovine carboxypeptidase A
分子名称: Carboxypeptidase A1, Metallocarboxypeptidase inhibitor, ZINC ION
著者Arolas, J.L, Popowicz, G.M, Bronsoms, S, Aviles, F.X, Huber, R, Holak, T.A, Ventura, S.
登録日2005-07-18
公開日2006-01-31
最終更新日2021-11-10
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Study of a major intermediate in the oxidative folding of leech carboxypeptidase inhibitor: contribution of the fourth disulfide bond
J.Mol.Biol., 352, 2005
2AC0
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Structural Basis of DNA Recognition by p53 Tetramers (complex I)
分子名称: 5'-D(*CP*GP*GP*GP*CP*AP*TP*GP*CP*CP*CP*G)-3', Cellular tumor antigen p53, ZINC ION
著者Kitayner, M, Rozenberg, H, Kessler, N, Rabinovich, D, Shakked, Z.
登録日2005-07-18
公開日2006-07-11
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural Basis of DNA Recognition by p53 Tetramers
Mol.Cell, 22, 2006

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