2ABE
Carbonic anhydrase activators: X-ray crystal structure of the adduct of human isozyme II with L-histidine as a platform for the design of stronger activators
Summary for 2ABE
Entry DOI | 10.2210/pdb2abe/pdb |
Descriptor | Carbonic anhydrase II, ZINC ION, MERCURY (II) ION, ... (5 entities in total) |
Functional Keywords | protein-activator complex, lyase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm : P00918 |
Total number of polymer chains | 1 |
Total formula weight | 29780.61 |
Authors | Temperini, C.,Scozzafava, A.,Puccetti, L.,Supuran, C.T. (deposition date: 2005-07-15, release date: 2005-10-25, Last modification date: 2024-02-14) |
Primary citation | Temperini, C.,Scozzafava, A.,Puccetti, L.,Supuran, C.T. Carbonic anhydrase activators: X-ray crystal structure of the adduct of human isozyme II with l-histidine as a platform for the design of stronger activators. Bioorg.Med.Chem.Lett., 15:5136-5141, 2005 Cited by PubMed: 16214338DOI: 10.1016/j.bmcl.2005.08.069 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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