2ABE

Carbonic anhydrase activators: X-ray crystal structure of the adduct of human isozyme II with L-histidine as a platform for the design of stronger activators

Summary for 2ABE
DescriptorCarbonic anhydrase II, ZINC ION, MERCURY (II) ION, ... (5 entities in total)
Functional Keywordsprotein-activator complex, lyase
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm : P00918
Total number of polymer chains1
Total formula weight29780.61
Authors
Temperini, C.,Scozzafava, A.,Puccetti, L.,Supuran, C.T. (deposition date: 2005-07-15, release date: 2005-10-25, Last modification date: 2011-07-13)
Primary citationPuccetti, L.,Scozzafava, A.,Supuran, C.T.,Temperini, C.
Carbonic anhydrase activators: X-ray crystal structure of the adduct of human isozyme II with l-histidine as a platform for the design of stronger activators.
Bioorg.Med.Chem.Lett., 15:5136-5141, 2005
PubMed: 16214338
DOI: 110.1016/j.bmcl.2005.08.069
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation
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PDB entries from 2021-06-09