2ABZ

Crystal structure of C19A/C43A mutant of leech carboxypeptidase inhibitor in complex with bovine carboxypeptidase A

Summary for 2ABZ

Related1DTD 1DTV 1ZFL
DescriptorCarboxypeptidase A1, Metallocarboxypeptidase inhibitor, ZINC ION (3 entities in total)
Functional Keywordsinhibitor-metallocarboxypeptidase complex, lci mutant, oxidative folding intermediate analog, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceBos taurus (cattle)
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Cellular locationSecreted, extracellular space P00730
Total number of polymer chains6
Total molecular weight98906.82
Authors
Arolas, J.L.,Popowicz, G.M.,Bronsoms, S.,Aviles, F.X.,Huber, R.,Holak, T.A.,Ventura, S. (deposition date: 2005-07-18, release date: 2006-01-31, Last modification date: 2011-07-13)
Primary citation
Arolas, J.L.,Popowicz, G.M.,Bronsoms, S.,Aviles, F.X.,Huber, R.,Holak, T.A.,Ventura, S.
Study of a major intermediate in the oxidative folding of leech carboxypeptidase inhibitor: contribution of the fourth disulfide bond
J.Mol.Biol., 352:961-975, 2005
PubMed: 16126224 (PDB entries with the same primary citation)
DOI: 10.1016/j.jmb.2005.07.065
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.16 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliers0.257150.4%4.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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