2AC0

Structural Basis of DNA Recognition by p53 Tetramers (complex I)

Summary for 2AC0

• Entry DOI: 10.2210/pdb2ac0/pdb
• Related: 2ADY 2AHI 2ATA
• Descriptor: 5'-D(*CP*GP*GP*GP*CP*AP*TP*GP*CP*CP*CP*G)-3', Cellular tumor antigen p53, ZINC ION, ... (4 entities in total)
• Functional Keywords: protein-dna complex, apoptosis-dna complex, apoptosis/dna
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm. Isoform 1: Nucleus. Isoform 2: Nucleus. Isoform 3: Nucleus. Isoform 4: Nucleus. Isoform 7: Nucleus. Isoform 8: Nucleus. Isoform 9: Cytoplasm: P04637
• Total number of polymer chains: 8
• Total formula weight: 104941.48

Authors

Kitayner, M.,Rozenberg, H.,Kessler, N.,Rabinovich, D.,Shakked, Z. (deposition date: 2005-07-18, release date: 2006-07-11, Last modification date: 2023-10-25)

• Primary citation: Kitayner, M.,Rozenberg, H.,Kessler, N.,Rabinovich, D.,Shaulov, L.,Haran, T.E.,Shakked, Z.; Structural Basis of DNA Recognition by p53 Tetramers; Mol.Cell, 22:741-753, 2006; PubMed: 16793544; DOI: 10.1016/j.molcel.2006.05.015

Experimental method

X-RAY DIFFRACTION (1.8 Å)