2ABM

Crystal Structure of Aquaporin Z Tetramer Reveals both Open and Closed Water-conducting Channels

Summary for 2ABM

Related1fx8 1rc2
DescriptorAquaporin Z, B-2-OCTYLGLUCOSIDE, BIS(((3S,4S,5R,6R)-5-(ETHYL(PHOSPHORYLOXY))-3,4,6-TRIHYDROXY-TETRAHYDRO-2H-PYRAN-2-YL)METHYL) HYDROGEN PHOSPHATE, ... (8 entities in total)
Functional Keywordsaquaporin, membrane protein
Biological sourceEscherichia coli
Cellular locationCell inner membrane ; Multi- pass membrane protein  P60844
Total number of polymer chains8
Total molecular weight198455.54
Authors
Jiang, J.,Daniels, B.V.,Fu, D. (deposition date: 2005-07-15, release date: 2005-09-20, Last modification date: 2014-10-29)
Primary citation
Jiang, J.,Daniels, B.V.,Fu, D.
Crystal Structure of AqpZ Tetramer Reveals Two Distinct Arg-189 Conformations Associated with Water Permeation through the Narrowest Constriction of the Water-conducting Channel.
J.Biol.Chem., 281:454-460, 2006
PubMed: 16239219 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M508926200
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3.2 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.247343.6%4.8%0.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2abm
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Molmil generated image of 2abm
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Molmil generated image of 2abm
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More Biological unit images

Molmil generated image of 2abm
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Molmil generated image of 2abm
rotated about x axis by 90°
Molmil generated image of 2abm
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (2abm.pdb5.gz [553.9 KB])
Coordinate files for Biological unit (2abm.pdb3.gz [554.46 KB])
Coordinate files for Biological unit (2abm.pdb7.gz [278.61 KB])
Coordinate files for Biological unit (2abm.pdb2.gz [140.98 KB])
Coordinate files for Biological unit (2abm.pdb1.gz [141.46 KB])
Coordinate files for Biological unit (2abm.pdb6.gz [551.63 KB])
Coordinate files for Biological unit (2abm.pdb8.gz [278.07 KB])
Coordinate files for Biological unit (2abm.pdb4.gz [553.97 KB])