5L5Z
 
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8WGR
 | | Cryo-EM structure of inward-open state human norepinephrine transporter NET bound with antidepressant desipramine in KCl condition. | | 分子名称: | 3-(10,11-DIHYDRO-5H-DIBENZO[B,F]AZEPIN-5-YL)-N-METHYLPROPAN-1-AMINE, CHLORIDE ION, POTASSIUM ION, ... | | 著者 | Tan, J, Xiao, Y, Kong, F, Lei, J, Yuan, Y, Yan, C. | | 登録日 | 2023-09-22 | | 公開日 | 2024-07-31 | | 最終更新日 | 2024-08-07 | | 実験手法 | ELECTRON MICROSCOPY (2.75 Å) | | 主引用文献 | Molecular basis of human noradrenaline transporter reuptake and inhibition.
Nature, 2024
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5L6C
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8WGX
 | | Cryo-EM structure of inward-open state human norepinephrine transporter NET bound with norepinephrine in nanodisc. | | 分子名称: | L-NOREPINEPHRINE, Sodium-dependent noradrenaline transporter | | 著者 | Tan, J, Xiao, Y, Kong, F, Lei, J, Yuan, Y, Yan, C. | | 登録日 | 2023-09-22 | | 公開日 | 2024-07-31 | | 最終更新日 | 2024-08-07 | | 実験手法 | ELECTRON MICROSCOPY (3.47 Å) | | 主引用文献 | Molecular basis of human noradrenaline transporter reuptake and inhibition.
Nature, 2024
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6G26
 | | The crystal structure of the Burkholderia pseudomallei HicAB complex | | 分子名称: | 1,2-ETHANEDIOL, HicA, HicB, ... | | 著者 | Winter, A.J, Isupov, M.N, Williams, C, Crump, M.P. | | 登録日 | 2018-03-22 | | 公開日 | 2018-10-31 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | | 主引用文献 | The molecular basis of protein toxin HicA-dependent binding of the protein antitoxin HicB to DNA.
J. Biol. Chem., 293, 2018
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6GEN
 | | Chromatin remodeller-nucleosome complex at 4.5 A resolution. | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin-like protein ARP6, BERYLLIUM TRIFLUORIDE ION, ... | | 著者 | Willhoft, O, Chua, E.Y.D, Wilkinson, M, Wigley, D.B. | | 登録日 | 2018-04-27 | | 公開日 | 2018-10-17 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structure and dynamics of the yeast SWR1-nucleosome complex.
Science, 362, 2018
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5L9E
 | | CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH A QUINOLINE OLIGOAMIDE FOLDAMER | | 分子名称: | 8-azanyl-4-(2-hydroxy-2-oxoethyloxy)quinoline-2-carboxylic acid, 8-azanyl-4-(2-methylpropoxy)quinoline-2-carboxylic acid, Carbonic anhydrase 2, ... | | 著者 | Vallade, M, Langlois d'Estaintot, B, Granier, T, Huc, I. | | 登録日 | 2016-06-10 | | 公開日 | 2017-06-21 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH A QUINOLINE OLIGOAMIDE FOLDAMER
To Be Published
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8WCL
 | | FCP pentamer in Chaetoceros gracilis | | 分子名称: | (3S,3'S,5R,5'R,6S,6'R,8'R)-3,5'-dihydroxy-8-oxo-6',7'-didehydro-5,5',6,6',7,8-hexahydro-5,6-epoxy-beta,beta-caroten-3'- yl acetate, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, CHLOROPHYLL A, ... | | 著者 | Feng, Y, Li, Z, Zhou, C, Liu, C, Shen, J.-R, Wang, W. | | 登録日 | 2023-09-12 | | 公開日 | 2024-07-31 | | 実験手法 | ELECTRON MICROSCOPY (2.65 Å) | | 主引用文献 | Structural and spectroscopic insights into fucoxanthin chlorophyll a/c-binding proteins of diatoms in diverse oligomeric states.
Plant Commun., 2024
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8WCK
 | | FCP tetramer in Chaetoceros gracilis | | 分子名称: | (3S,3'S,5R,5'R,6S,6'R,8'R)-3,5'-dihydroxy-8-oxo-6',7'-didehydro-5,5',6,6',7,8-hexahydro-5,6-epoxy-beta,beta-caroten-3'- yl acetate, CHLOROPHYLL A, Chlorophyll a/b-binding protein, ... | | 著者 | Feng, Y, Li, Z, Zhou, C, Shen, J.-R, Liu, C, Wang, W. | | 登録日 | 2023-09-12 | | 公開日 | 2024-07-31 | | 実験手法 | ELECTRON MICROSCOPY (2.71 Å) | | 主引用文献 | Structural and spectroscopic insights into fucoxanthin chlorophyll a/c-binding proteins of diatoms in diverse oligomeric states.
Plant Commun., 2024
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6GEJ
 | | Chromatin remodeller-nucleosome complex at 3.6 A resolution. | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin-like protein ARP6, BERYLLIUM TRIFLUORIDE ION, ... | | 著者 | Willhoft, O, Chua, E.Y.D, Wilkinson, M, Wigley, D.B. | | 登録日 | 2018-04-26 | | 公開日 | 2018-10-17 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structure and dynamics of the yeast SWR1-nucleosome complex.
Science, 362, 2018
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8W4D
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6QPH
 | | Dunaliella minimal PSI complex | | 分子名称: | (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, ... | | 著者 | Klaiman, D, Caspy, I, Nelson, N. | | 登録日 | 2019-02-14 | | 公開日 | 2020-02-12 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Structure of a minimal photosystem I from the green alga Dunaliella salina.
Nat.Plants, 6, 2020
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8VTW
 | | Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with macrolone MCX-128 and protein Y at 2.35A resolution | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1-cyclopropyl-7-(4-{4-[({[(3aR,4R,7R,8S,9S,10R,11R,13R,14E,15S,15aR)-10-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-4-ethyl-11-methoxy-14-(methoxyimino)-3a,7,9,11,13,15-hexamethyl-2,6-dioxododecahydro-2H,4H-[1,3]dioxolo[4,5-c]oxacyclotetradecin-8-yl]oxy}carbonyl)amino]butyl}piperazin-1-yl)-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (non-preferred name), 16S Ribosomal RNA, ... | | 著者 | Aleksandrova, E.V, Ma, C.-X, Klepacki, D, Alizadeh, F, Vazquez-Laslop, N, Liang, J.-H, Polikanov, Y.S, Mankin, A.S. | | 登録日 | 2024-01-27 | | 公開日 | 2024-08-07 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Macrolones target bacterial ribosomes and DNA gyrase and can evade resistance mechanisms.
Nat.Chem.Biol., 2024
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8VTU
 | | Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with macrolone MCX-66, mRNA, aminoacylated A-site Phe-tRNAphe, aminoacylated P-site fMet-tRNAmet, and deacylated E-site tRNAphe at 2.40A resolution | | 分子名称: | 1-cyclopropyl-7-[(4-{[3-({(3aR,4R,7R,8S,9S,10R,11R,13R,14E,15S,15aR)-10-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-4-ethyl-11-methoxy-3a,7,9,11,13,15-hexamethyl-14-[({3-[5-(methylcarbamoyl)pyridin-3-yl]prop-2-yn-1-yl}oxy)imino]-2,6-dioxododecahydro-2H,4H-[1,3]dioxolo[4,5-c]oxacyclotetradecin-8-yl}oxy)-3-oxopropyl]amino}butyl)amino]-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (non-preferred name), 16S Ribosomal RNA, 23S Ribosomal RNA, ... | | 著者 | Aleksandrova, E.V, Ma, C.-X, Klepacki, D, Alizadeh, F, Vazquez-Laslop, N, Liang, J.-H, Polikanov, Y.S, Mankin, A.S. | | 登録日 | 2024-01-27 | | 公開日 | 2024-08-07 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Macrolones target bacterial ribosomes and DNA gyrase and can evade resistance mechanisms.
Nat.Chem.Biol., 2024
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6G4U
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6G4I
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5L5B
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6G4K
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6BZ8
 | | Thermus thermophilus 70S containing 16S G347U point mutation and near-cognate ASL Leucine in A site | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | 著者 | Hoffer, E.D, Maehigashi, T, Fagan, C.E, Dunham, C.M. | | 登録日 | 2017-12-22 | | 公開日 | 2018-11-14 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3.74 Å) | | 主引用文献 | Ribosomal ambiguity (ram) mutations promote the open (off) to closed (on) transition and thereby increase miscoding.
Nucleic Acids Res., 47, 2019
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5L5W
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6G4V
 | | The solution NMR structure of [C18S,C24S]brevinin-1BYa in 33% trifluoroethanol | | 分子名称: | [C18S,C24S]brevinin-1BYa | | 著者 | Timmons, P.B, O'Flynn, D.P, Conlon, J.M, Hewage, C.M. | | 登録日 | 2018-03-28 | | 公開日 | 2019-10-16 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Insights into conformation and membrane interactions of the acyclic and dicarba-bridged brevinin-1BYa antimicrobial peptides.
Eur.Biophys.J., 48, 2019
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5KZP
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6G4X
 | | The solution NMR structure of [C18S,C24S]brevinin-1BYa in sodium dodecyl sulphate micelles | | 分子名称: | [C18S,C24S]brevinin-1BYa | | 著者 | Timmons, P.B, O'Flynn, D.P, Conlon, J.M, Hewage, C.M. | | 登録日 | 2018-03-28 | | 公開日 | 2019-10-16 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Insights into conformation and membrane interactions of the acyclic and dicarba-bridged brevinin-1BYa antimicrobial peptides.
Eur.Biophys.J., 48, 2019
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6QWV
 | | SARM1 SAM1-2 domains | | 分子名称: | 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Sporny, M, Isupov, N.M, Opatowsky, Y. | | 登録日 | 2019-03-06 | | 公開日 | 2019-07-03 | | 最終更新日 | 2019-09-18 | | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | | 主引用文献 | Structural Evidence for an Octameric Ring Arrangement of SARM1.
J.Mol.Biol., 431, 2019
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6QXP
 | | Protein peptide complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Leucine-rich repeat extensin-like protein 2, ... | | 著者 | Moussu, S, Caroline, C, Santos-Fernandez, G, Wehrle, S, Grossniklaus, U, Santiago, J. | | 登録日 | 2019-03-07 | | 公開日 | 2020-03-25 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.201 Å) | | 主引用文献 | Structural basis for recognition of RALF peptides by LRX proteins during pollen tube growth.
Proc.Natl.Acad.Sci.USA, 117, 2020
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