5L9E

CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH A QUINOLINE OLIGOAMIDE FOLDAMER

Summary for 5L9E

DescriptorCarbonic anhydrase 2, ZINC ION, ~{N}-[[3-(4-formamidobutoxy)phenyl]methyl]-4-sulfamoyl-benzamide, ... (7 entities in total)
Functional Keywordsprotein-foldamer complex, protein foldamer interactions, modified inhibitor, anchored foldamer, hcaii dimerisation, quinoline oligoamide foldamer, benzene sulfonamide modified inhibitor, lyase-inhibitor complex, lyase/inhibitor
Biological sourceHomo sapiens (Human)
Total number of polymer chains4
Total molecular weight125092.59
Authors
Vallade, M.,Langlois d'Estaintot, B.,Granier, T.,Huc, I. (deposition date: 2016-06-10, release date: 2017-06-21, Last modification date: 2019-06-12)
Primary citation
Vallade, M.,Fischer, L.,Langlois d'Estaintot, B.,Granier, T.,Huc, I.
CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH A QUINOLINE OLIGOAMIDE FOLDAMER
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.9 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2740 0.1% 0.9% 2.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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171588
PDB entries from 2020-11-25