Structure of the HCV1-C1 Antibody-Antigen Complex

Summary for 5KZP

DescriptorHCV1-C1 Antibody Fab Heavy Chain, HCV1-C1 Antibody Fab Light Chain, C1 Epitope, ... (6 entities in total)
Functional Keywordsantibody, antigen, hcv, vaccine, virology, viral protein-immune system complex, viral protein/immune system
Biological sourceHomo sapiens
Total number of polymer chains12
Total molecular weight199916.16
Piepenbrink, K.H.,Sundberg, E.J. (deposition date: 2016-07-25, release date: 2017-07-05, Last modification date: 2017-10-11)
Primary citation
Pierce, B.G.,Boucher, E.N.,Piepenbrink, K.H.,Ejemel, M.,Rapp, C.A.,Thomas, W.D.,Sundberg, E.J.,Weng, Z.,Wang, Y.
Structure-Based Design of Hepatitis C Virus Vaccines That Elicit Neutralizing Antibody Responses to a Conserved Epitope.
J. Virol., 91:-, 2017
PubMed: 28794021 (PDB entries with the same primary citation)
DOI: 10.1128/JVI.01032-17
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.26117 0.3% 2.1% 27.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-10-14