8W4D

Crystal structure of the sigma-1 receptor from Xenopus laevis in the absence of known ligands

Summary for 8W4D

Entry DOI	10.2210/pdb8w4d/pdb
Descriptor	Sigma non-opioid intracellular receptor 1 (2 entities in total)
Functional Keywords	sigma receptor, s1r, endogenous ligand, neurosteroid, p4, membrane protein
Biological source	Xenopus laevis (African clawed frog)
Total number of polymer chains	1
Total formula weight	25720.32
Authors	Xiao, Y.,Fu, C.,Sun, Z.,Zhou, X. (deposition date: 2023-08-23, release date: 2024-07-17)
Primary citation	Fu, C.,Xiao, Y.,Zhou, X.,Sun, Z. Insight into binding of endogenous neurosteroid ligands to the sigma-1 receptor. Nat Commun, 15:5619-5619, 2024 Cited by PubMed: 38965213 DOI: 10.1038/s41467-024-49894-7 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.173 Å)

Structure validation