PDB: 46188 件ウェブページステータス検索Chemie searchBIRD

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7LFH	Cryo-EM structure of NLRP3 double-ring cage, 6-fold (12-mer) 分子名称: NACHT, LRR and PYD domains-containing protein 3 著者 Andreeva, L, Rawson, S, Wu, H. 登録日 2021-01-17 公開日 2021-12-15 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 NLRP3 cages revealed by full-length mouse NLRP3 structure control pathway activation. Cell, 184, 2021
3O1C	High resolution crystal structure of histidine triad nucleotide-binding protein 1 (Hint1) C38A mutant from rabbit complexed with Adenosine 分子名称: ADENOSINE, Histidine triad nucleotide-binding protein 1, SODIUM ION 著者 Dolot, R.M, Ozga, M, Krakowiak, A.K, Nawrot, B, Stec, W.J. 登録日 2010-07-21 公開日 2010-08-04 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.08 Å) 主引用文献 Histidine Triad Nucleotide-binding Protein 1 (HINT-1) Phosphoramidase Transforms Nucleoside 5'-O-Phosphorothioates to Nucleoside 5'-O-Phosphates. J.Biol.Chem., 285, 2010
3O1X	High resolution crystal structure of histidine triad nucleotide-binding protein 1 (Hint1) C84A mutant from rabbit complexed with adenosine 分子名称: ADENOSINE, Histidine triad nucleotide-binding protein 1, SODIUM ION 著者 Dolot, R.M, Ozga, M, Krakowiak, A.K, Nawrot, B, Stec, W.J. 登録日 2010-07-22 公開日 2010-08-04 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.08 Å) 主引用文献 Histidine Triad Nucleotide-binding Protein 1 (HINT-1) Phosphoramidase Transforms Nucleoside 5'-O-Phosphorothioates to Nucleoside 5'-O-Phosphates. J.Biol.Chem., 285, 2010
3O1Z	High resolution crystal structure of histidine triad nucleotide-binding protein 1 (Hint1) double cysteine mutant from rabbit 分子名称: Histidine triad nucleotide-binding protein 1 著者 Dolot, R.M, Ozga, M, Krakowiak, A.K, Nawrot, B, Stec, W.J. 登録日 2010-07-22 公開日 2010-08-04 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Histidine Triad Nucleotide-binding Protein 1 (HINT-1) Phosphoramidase Transforms Nucleoside 5'-O-Phosphorothioates to Nucleoside 5'-O-Phosphates. J.Biol.Chem., 285, 2010
3NOO	Crystal Structure of C101A Isocyanide Hydratase from Pseudomonas fluorescens 分子名称: 1,2-ETHANEDIOL, ACETATE ION, ThiJ/PfpI family protein 著者 Lakshminarasimhan, M, Madzelan, P, Nan, R, Milkovic, N.M, Wilson, M.A. 登録日 2010-06-25 公開日 2010-07-07 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.03 Å) 主引用文献 Evolution of New Enzymatic Function by Structural Modulation of Cysteine Reactivity in Pseudomonas fluorescens Isocyanide Hydratase. J.Biol.Chem., 285, 2010
3FLQ	P38 kinase crystal structure in complex with 6-(2,4-difluoro-phenoxy)-2-((s)-2-methanesulfonyl-1-methyl-ethylamino)-8-methyl-8h-pyrido[2,3-d]pyrimidin 分子名称: 6-(2,4-difluorophenoxy)-8-methyl-2-{[(1S)-1-methyl-2-(methylsulfonyl)ethyl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one, Mitogen-activated protein kinase 14 著者 Kuglstatter, A, Knapp, M. 登録日 2008-12-19 公開日 2009-12-22 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The Discovery of Pamapimod, R1503 and R1487 as Orally Bioavailable and Highly Selective Inhibitors of p38 Map Kinase To be Published
4US7	Sulfur SAD Phased Structure of a Type IV Pilus Protein from Shewanella oneidensis 分子名称: PILD PROCESSED PROTEIN, SODIUM ION, SULFATE ION 著者 Gorgel, M, Boeggild, A, Ulstrup, J.J, Mueller, U, Weiss, M, Nissen, P, Boesen, T. 登録日 2014-07-03 公開日 2015-04-29 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 High-Resolution Structure of a Type Iv Pilin from the Metal- Reducing Bacterium Shewanella Oneidensis. Bmc Struct.Biol., 15, 2015
4W6Z	YEAST ALCOHOL DEHYDROGENASE I, SACCHAROMYCES CEREVISIAE FERMENTATIVE ENZYME 分子名称: Alcohol dehydrogenase 1, NICOTINAMIDE-8-IODO-ADENINE-DINUCLEOTIDE, TRIFLUOROETHANOL, ... 著者 plapp, B.v, savarimuthu, b.r, ramaswamy, s. 登録日 2014-08-21 公開日 2014-09-03 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Yeast alcohol dehydrogenase structure and catalysis. Biochemistry, 53, 2014
4E5B	Structure of p38a MAP kinase without BOG 分子名称: Mitogen-activated protein kinase 14 著者 Livnah, O, Eisenberg-Domovich, Y, Tzarum, N. 登録日 2012-03-14 公開日 2012-10-31 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Lipid Molecules Induce p38 alpha Activation via a Novel Molecular Switch. J.Mol.Biol., 424, 2012
4W60	The structure of Vaccina virus H7 protein displays A Novel Phosphoinositide binding fold required for membrane biogenesis 分子名称: Late protein H7 著者 Kolli, S, Meng, X, Wu, X, Shengjuler, D, Cameron, C.E, Xiang, Y, Deng, J. 登録日 2014-08-19 公開日 2014-12-31 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structure-function analysis of vaccinia virus h7 protein reveals a novel phosphoinositide binding fold essential for poxvirus replication. J.Virol., 89, 2015
2NPQ	A Novel Lipid Binding Site in the p38 alpha MAP Kinase 分子名称: Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside 著者 Diskin, R, Engelberg, D, Livnah, O. 登録日 2006-10-29 公開日 2007-10-16 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A novel lipid binding site formed by the MAP kinase insert in p38 alpha. J.Mol.Biol., 375, 2008
4EH6	Human p38 MAP kinase in complex with NP-F5 and RL87 分子名称: Mitogen-activated protein kinase 14, N-phenylpyridine-3-carboxamide, N~4~-cyclopropyl-2-phenylquinazoline-4,7-diamine 著者 Over, B, Gruetter, C, Waldmann, H, Rauh, D. 登録日 2012-04-02 公開日 2012-12-05 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Natural-product-derived fragments for fragment-based ligand discovery. Nat Chem, 5, 2012
3FI4	P38 kinase crystal structure in complex with RO4499 分子名称: (2S)-1-{[3-(2-chlorophenyl)-6-(2,4-difluorophenoxy)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]amino}propan-2-ol, Mitogen-activated protein kinase 14 著者 Kuglstatter, A, Knapp, M, Dunten, P. 登録日 2008-12-10 公開日 2009-12-22 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Mapping Binding Pocket Volume: Potential Applications towards Ligand Design and Selectivity To be Published
3FMN	P38 kinase crystal structure in complex with RO2530 分子名称: 6-(2,4-difluorophenoxy)-N-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-3-amine, Mitogen-activated protein kinase 14 著者 Kuglstatter, A, Ghate, M. 登録日 2008-12-22 公開日 2009-12-22 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 P38 kinase crystal structure in complex with RO2530 To be Published
3FMK	P38 kinase crystal structure in complex with 6-(2,4-Difluoro-phenoxy)-8-methyl-2-((S)-1-methyl-2-tetrazol-2-yl-ethylamino)-8H-pyrido[2,3-d]pyrimidin-7-one 分子名称: 6-(2,4-difluorophenoxy)-8-methyl-2-{[(1S)-1-methyl-2-(2H-tetrazol-2-yl)ethyl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one, Mitogen-activated protein kinase 14 著者 Kuglstatter, A, Ghate, M. 登録日 2008-12-22 公開日 2009-12-22 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 The Discovery of Pamapimod and R1487 as Orally Bioavailable and Highly Selective Inhibitors of p38 Map Kinase To be Published
3OB9	Structure of the human MSL3 chromo-barrel domain at 2.5 Angstrom resolution 分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Male-specific lethal 3-like 1 (Drosophila), isoform CRA_c, ... 著者 Moore, S.A, Ferhatoglu, Y. 登録日 2010-08-06 公開日 2010-10-13 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure of the human MSL3 chromo-barrel domain at 2.5 Angstrom resolution J.Biol.Chem., 2010
3OD4	Crystal Structure of Factor Inhibiting HIF-1 Alpha Complexed with Inhibitor 分子名称: 8-hydroxyquinoline-5-carboxylic acid, GLYCEROL, Hypoxia-inducible factor 1-alpha inhibitor, ... 著者 King, O.N.F, Bashford-Rogers, R, Maloney, D.J, Jadhav, A, Heightman, T.D, Simeonov, A, Clifton, I.J, McDonough, M.A, Schofield, C.J. 登録日 2010-08-10 公開日 2011-07-06 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal Structure of Factor Inhibiting HIF-1 Alpha Complexed with Inhibitor To be Published
4EM9	Human PPAR gamma in complex with nonanoic acids 分子名称: 3,3',3''-phosphanetriyltripropanoic acid, GLYCEROL, Peroxisome proliferator-activated receptor gamma, ... 著者 Liberato, M.V, Nascimento, A.S, Polikarpov, I. 登録日 2012-04-11 公開日 2013-03-06 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Medium chain fatty acids are selective peroxisome proliferator activated receptor (PPAR) Gamma activators and pan-PPAR partial agonists Plos One, 7, 2012
4EH7	Human p38 MAP kinase in complex with NP-F6 and RL87 分子名称: (3-phenoxyphenyl)methanol, Mitogen-activated protein kinase 14, N~4~-cyclopropyl-2-phenylquinazoline-4,7-diamine 著者 Over, B, Gruetter, C, Waldmann, H, Rauh, D. 登録日 2012-04-02 公開日 2012-12-05 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Natural-product-derived fragments for fragment-based ligand discovery. Nat Chem, 5, 2012
3DS6	P38 complex with a phthalazine inhibitor 分子名称: Mitogen-activated protein kinase 14, N-cyclopropyl-4-methyl-3-[1-(2-methylphenyl)phthalazin-6-yl]benzamide 著者 Herberich, B, Syed, R, Li, V, Grosfeld, D. 登録日 2008-07-11 公開日 2008-10-07 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Discovery of highly selective and potent p38 inhibitors based on a phthalazine scaffold. J.Med.Chem., 51, 2008
3OL9	Poliovirus polymerase elongation complex with 3'-deoxy-CTP 分子名称: ISOPROPYL ALCOHOL, PYROPHOSPHATE 2-, Polymerase, ... 著者 Gong, P, Peersen, O.B. 登録日 2010-08-25 公開日 2010-12-22 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structural basis for active site closure by the poliovirus RNA-dependent RNA polymerase. Proc.Natl.Acad.Sci.USA, 107, 2010
7CCI	Acinetobacter baumannii response regulator AdeR with disordered N terminus 分子名称: AdeR, MAGNESIUM ION 著者 Wen, Y. 登録日 2020-06-17 公開日 2021-06-23 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Proteolysis and multimerization regulate signaling along the two-component regulatory system AdeRS. Iscience, 24, 2021
5JUS	Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura Syndrome Virus IRES, Structure III (mid-rotated 40S subunit) 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 5.8S ribosomal RNA, ... 著者 Abeyrathne, P, Koh, C.S, Grant, T, Grigorieff, N, Korostelev, A.A. 登録日 2016-05-10 公開日 2016-10-05 最終更新日 2023-04-05 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome. Elife, 5, 2016
3OLO	Crystal structure of a PAS domain from two-component sensor histidine kinase 分子名称: GLYCEROL, Two-component sensor histidine kinase 著者 Michalska, K, Chhor, G, Bearden, J, Fenske, R.J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2010-08-26 公開日 2010-09-15 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.094 Å) 主引用文献 Crystal structure of a PAS domain from two-component sensor histidine kinase To be Published
3OL7	Poliovirus polymerase elongation complex with CTP 分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, ISOPROPYL ALCOHOL, ... 著者 Gong, P, Peersen, O.B. 登録日 2010-08-25 公開日 2010-12-22 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural basis for active site closure by the poliovirus RNA-dependent RNA polymerase. Proc.Natl.Acad.Sci.USA, 107, 2010

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