PDB: 47120 件ウェブページステータス検索Chemie searchBIRD

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5UTU	2.65 Angstrom Resolution Crystal Structure of S-adenosylhomocysteinase from Cryptosporidium parvum in Complex with SAH and NAD 分子名称: 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, ADENOSINE, Adenosylhomocysteinase, ... 著者 Minasov, G, Shuvalova, L, Dubrovska, I, Winsor, J, Stam, J, Kwon, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2017-02-15 公開日 2017-03-01 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 2.65 Angstrom Resolution Crystal Structure of S-adenosylhomocysteinase from Cryptosporidium parvum in Complex with SAH and NAD To Be Published
5G6E	Structure of Bacillus subtilis Nitric Oxide Synthase in complex with 7-(((3-(Pyridin-3-yl)propyl)amino)methyl)quinolin-2-amine 分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, 7-(((3-(PYRIDIN-3-YL)PROPYL)AMINO)METHYL)QUINOLIN-2-, CHLORIDE ION, ... 著者 Holden, J.K, Poulos, T.L. 登録日 2016-06-18 公開日 2016-09-21 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.111 Å) 主引用文献 Targeting Bacterial Nitric Oxide Synthase with Aminoquinoline-Based Inhibitors. Biochemistry, 55, 2016
3X02	Crystal structure of PIP4KIIBETA complex with GMP 分子名称: GUANOSINE-5'-MONOPHOSPHATE, Phosphatidylinositol 5-phosphate 4-kinase type-2 beta 著者 Takeuchi, K, Lo, Y.H, Sumita, K, Senda, M, Terakawa, J, Dimitoris, A, Locasale, J.W, Sasaki, M, Yoshino, H, Zhang, Y, Kahoud, E.R, Takano, T, Yokota, T, Emerling, B, Asara, J.A, Ishida, T, Shimada, I, Daikoku, T, Cantley, L.C, Senda, T, Sasaki, A.T. 登録日 2014-10-09 公開日 2015-10-14 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 The Lipid Kinase PI5P4K beta Is an Intracellular GTP Sensor for Metabolism and Tumorigenesis Mol.Cell, 61, 2016
5UI5	Crystal structure of Aquifex aeolicus sigmaN bound to promoter DNA 分子名称: DNA (30-MER), DNA (31-MER), RNA polymerase sigma factor RpoN 著者 Darst, S.A, Campbell, E.A, Rajashankar, K. 登録日 2017-01-12 公開日 2017-02-22 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Crystal structure of Aquifex aeolicus sigma (N) bound to promoter DNA and the structure of sigma (N)-holoenzyme. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5UM0	Crystal structure of 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase from Neisseria gonorrhoeae 分子名称: 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, L(+)-TARTARIC ACID 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2017-01-25 公開日 2017-02-15 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Crystal structure of 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase from Neisseria gonorrhoeae TO BE PUBLISHED
5UNJ	Structure of Human Liver Receptor Homolog 1 in complex with PGC1a and RJW100 分子名称: (1R,3aR,6aR)-5-hexyl-4-phenyl-3a-(1-phenylethenyl)-1,2,3,3a,6,6a-hexahydropentalen-1-ol, Nuclear receptor subfamily 5 group A member 2, Peroxisome proliferator-activated gamma coactivator 1-alpha 著者 Mays, S.G, Ortlund, E.A. 登録日 2017-01-31 公開日 2017-04-19 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.959 Å) 主引用文献 Structure and Dynamics of the Liver Receptor Homolog 1-PGC1 alpha Complex. Mol. Pharmacol., 92, 2017
5UO5	Structure of human neuronal nitric oxide synthase heme domain in complex with (RS)-3-[(2-amino-4-methylquinolin-7-yl)methoxy]-5-(2-(methylamino)propyl)benzonitrile 分子名称: 3-[(2-amino-4-methylquinolin-7-yl)methoxy]-5-[(2R)-2-(methylamino)propyl]benzonitrile, 3-[(2-amino-4-methylquinolin-7-yl)methoxy]-5-[(2S)-2-(methylamino)propyl]benzonitrile, 5,6,7,8-TETRAHYDROBIOPTERIN, ... 著者 Li, H, Poulos, T.L. 登録日 2017-01-31 公開日 2017-05-03 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Nitrile in the Hole: Discovery of a Small Auxiliary Pocket in Neuronal Nitric Oxide Synthase Leading to the Development of Potent and Selective 2-Aminoquinoline Inhibitors. J. Med. Chem., 60, 2017
5UJW	Crystal structure of triosephosphate isomerase from Francisella tularensis subsp. tularensis SCHU S4 分子名称: 1,2-ETHANEDIOL, 1,3-DIHYDROXYACETONEPHOSPHATE, CITRIC ACID, ... 著者 Chang, C, Maltseva, N, Kim, Y, Shatsman, S, Joachimiak, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2017-01-19 公開日 2017-02-08 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Crystal structure of triosephosphate isomerase from Francisella tularensis subsp. tularensis SCHU S4 To Be Published
3X0A	Crystal structure of PIP4KIIBETA F205L complex with GMP 分子名称: GUANOSINE-5'-MONOPHOSPHATE, Phosphatidylinositol 5-phosphate 4-kinase type-2 beta 著者 Takeuchi, K, Lo, Y.H, Sumita, K, Senda, M, Terakawa, J, Dimitoris, A, Locasale, J.W, Sasaki, M, Yoshino, H, Zhang, Y, Kahoud, E.R, Takano, T, Yokota, T, Emerling, B, Asara, J.A, Ishida, T, Shimada, I, Daikoku, T, Cantley, L.C, Senda, T, Sasaki, A.T. 登録日 2014-10-09 公開日 2015-10-14 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 The Lipid Kinase PI5P4K beta Is an Intracellular GTP Sensor for Metabolism and Tumorigenesis Mol.Cell, 61, 2016
5CNR	Crystal structure-guided design of self-assembling RNA nano triangles 分子名称: CHLORIDE ION, RNA (5'-R(*AP*GP*AP*GP*GP*AP*CP*GP*GP*CP*G)-3'), RNA (5'-R(*GP*UP*CP*UP*AP*CP*CP*CP*AP*CP*CP*UP*CP*GP*CP*C)-3') 著者 Boerneke, M, Dibrov, S, Hermann, T. 登録日 2015-07-18 公開日 2016-03-09 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.59 Å) 主引用文献 Crystal-Structure-Guided Design of Self-Assembling RNA Nanotriangles. Angew.Chem.Int.Ed.Engl., 55, 2016
5CNU	Crystal structure of the dATP inhibited E. coli class Ia ribonucleotide reductase complex bound to ADP and dGTP at 3.40 Angstroms resolution 分子名称: 2'-DEOXYADENOSINE-5'-DIPHOSPHATE, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ... 著者 Chen, P.Y.-T, Zimanyi, C.M, Funk, M.A, Drennan, C.L. 登録日 2015-07-18 公開日 2016-01-20 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Molecular basis for allosteric specificity regulation in class Ia ribonucleotide reductase from Escherichia coli. Elife, 5, 2016
5G6Q	Structure of Bacillus subtilis Nitric Oxide Synthase in complex with 7-(((5-((Methylamino)methyl)pyridin-3-yl)oxy)methyl) quinolin-2-amine 分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5,6,7,8-TETRAHYDROBIOPTERIN, 7-[[5-[(methylideneamino)methyl]pyridin-3-yl]oxymethyl]quinolin-2-amine, ... 著者 Holden, J.K, Poulos, T.L. 登録日 2016-06-18 公開日 2016-09-21 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Targeting Bacterial Nitric Oxide Synthase with Aminoquinoline-Based Inhibitors. Biochemistry, 55, 2016
2APJ	X-Ray Structure of Protein from Arabidopsis Thaliana AT4G34215 at 1.6 Angstrom Resolution 分子名称: Putative Esterase 著者 Wesenberg, G.E, Phillips Jr, G.N, Mccoy, J.G, Bitto, E, Bingman, C.A, Allard, S.T, Center for Eukaryotic Structural Genomics (CESG) 登録日 2005-08-16 公開日 2005-08-30 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 The structure at 1.6 Angstroms resolution of the protein product of the At4g34215 gene from Arabidopsis thaliana. Acta Crystallogr.,Sect.D, 61, 2005
5UP4	Structure of the HIV-1 Capsid Protein and spacer peptide 1 by Cryo-EM 分子名称: HIV-1 Capsid Protein and spacer peptide 1 著者 Perilla, J.R, Schirra, R, Zhang, P, Schulten, K. 登録日 2017-02-01 公開日 2017-12-06 最終更新日 2017-12-13 実験手法 ELECTRON MICROSCOPY (9 Å) 主引用文献 Quenching protein dynamics interferes with HIV capsid maturation. Nat Commun, 8, 2017
5BPO	Human insulin with intra-chain chemical crosslink between modified B27 and B29 分子名称: Insulin 著者 Brzozowski, A.M, Turkenburg, J.P, Jiracek, J, Zakova, L. 登録日 2015-05-28 公開日 2016-02-03 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Rational steering of insulin binding specificity by intra-chain chemical crosslinking. Sci Rep, 6, 2016
5UN1	Crystal structure of GluN1/GluN2B delta-ATD NMDA receptor 分子名称: (5S,10R)-5-methyl-10,11-dihydro-5H-5,10-epiminodibenzo[a,d][7]annulene, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Song, X, Gouaux, E. 登録日 2017-01-30 公開日 2018-02-07 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Mechanism of NMDA receptor channel block by MK-801 and memantine. Nature, 556, 2018
3ZHK	The crystal structure of single domain antibody 2x1 scaffold 分子名称: MG2X1 SCAFFOLD ANTIBODY, SULFATE ION 著者 Song, H.-N, Woo, E.-J, Lim, H.-K. 登録日 2012-12-22 公開日 2014-01-08 最終更新日 2014-07-16 実験手法 X-RAY DIFFRACTION (1.962 Å) 主引用文献 Directed Evolution of Human Heavy Chain Variable Domain (Vh) Using in Vivo Protein Fitness Filter. Plos One, 9, 2014
5ERA	Human Connexin-26 (Calcium-free) 分子名称: Gap junction beta-2 protein 著者 Purdy, M.D, Bennett, B.C, Baker, K.A, Yeager, M.J. 登録日 2015-11-13 公開日 2016-01-27 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 An electrostatic mechanism for Ca(2+)-mediated regulation of gap junction channels. Nat Commun, 7, 2016
5ERG	Crystal structure of the two-subunit tRNA m1A58 methyltransferase TRM6-TRM61 in complex with SAM 分子名称: S-ADENOSYLMETHIONINE, tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRM61, tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 著者 Zhu, Y, Wang, M, Wang, C, Fan, X, Jiang, X, Teng, M, Li, X. 登録日 2015-11-14 公開日 2016-09-14 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.202 Å) 主引用文献 Crystal structure of the two-subunit tRNA m(1)A58 methyltransferase TRM6-TRM61 from Saccharomyces cerevisiae. Sci Rep, 6, 2016
5UOT	CryoEM structure of the helical assembly of full length MxB 分子名称: Interferon-induced GTP-binding protein Mx2 著者 Perilla, J.R, Alvarez, F.J.D, Zhang, P, Schulten, K. 登録日 2017-02-01 公開日 2018-02-21 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (4.6 Å) 主引用文献 CryoEM structure of MxB reveals a novel oligomerization interface critical for HIV restriction. Sci Adv, 3, 2017
5AM5	ligand complex structure of soluble epoxide hydrolase 分子名称: 5-cyclohexyl-3-propyl-1H-pyridin-2-one, BIFUNCTIONAL EPOXIDE HYDROLASE 2, DIMETHYL SULFOXIDE 著者 Oster, L, Tapani, S, Xue, Y, Kack, H. 登録日 2015-03-09 公開日 2015-05-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.26 Å) 主引用文献 Successful Generation of Structural Information for Fragment-Based Drug Discovery. Drug Discov Today, 20, 2015
5ALO	ligand complex structure of soluble epoxide hydrolase 分子名称: 3-BENZYL-3-METHYL-5-(1-METHYLPYRAZOL-4-YL)INDOLIN-2-ONE, BIFUNCTIONAL EPOXIDE HYDROLASE 2, DIMETHYL SULFOXIDE 著者 Oster, L, Tapani, S, Xue, Y, Kack, H. 登録日 2015-03-08 公開日 2015-05-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Successful Generation of Structural Information for Fragment-Based Drug Discovery. Drug Discov Today, 20, 2015
5AM4	ligand complex structure of soluble epoxide hydrolase 分子名称: 5-cyclohexylspiro[1H-indole-3,4'-oxane]-2-one, BIFUNCTIONAL EPOXIDE HYDROLASE 2, DIMETHYL SULFOXIDE, ... 著者 Oster, L, Tapani, S, Xue, Y, Kack, H. 登録日 2015-03-09 公開日 2015-05-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Successful Generation of Structural Information for Fragment-Based Drug Discovery. Drug Discov Today, 20, 2015
5EEX	RADIATION DAMAGE TO THE TRAP-RNA COMPLEX: DOSE (DWD) 9.02 MGy 分子名称: (GAGUU)10GAG 53-NUCLEOTIDE RNA, TRYPTOPHAN, Transcription attenuation protein MtrB 著者 Bury, C.S, McGeehan, J.E, Garman, E.F, Shevtsov, M.B. 登録日 2015-10-23 公開日 2016-05-04 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 RNA protects a nucleoprotein complex against radiation damage. Acta Crystallogr D Struct Biol, 72, 2016
5ALT	ligand complex structure of soluble epoxide hydrolase 分子名称: 3-(2-methyltetrazol-5-yl)-5-(3-thienyl)pyridin-2-amine, BIFUNCTIONAL EPOXIDE HYDROLASE 2, DI(HYDROXYETHYL)ETHER, ... 著者 Oster, L, Tapani, S, Xue, Y, Kack, H. 登録日 2015-03-08 公開日 2015-05-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Successful Generation of Structural Information for Fragment-Based Drug Discovery. Drug Discov Today, 20, 2015

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