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3X0A

Crystal structure of PIP4KIIBETA F205L complex with GMP

Summary for 3X0A
Entry DOI10.2210/pdb3x0a/pdb
Related3WZZ 3X01 3X02 3X03 3X04 3X05 3X06 3X07 3X08 3X09 3X0B 3X0C
DescriptorPhosphatidylinositol 5-phosphate 4-kinase type-2 beta, GUANOSINE-5'-MONOPHOSPHATE (3 entities in total)
Functional Keywordslipid kinase, phosphoinositide signaling, transferase
Biological sourceHomo sapiens (human)
Cellular locationEndoplasmic reticulum membrane ; Peripheral membrane protein : P78356
Total number of polymer chains2
Total formula weight91605.88
Authors
Primary citationSumita, K.,Lo, Y.H.,Takeuchi, K.,Senda, M.,Kofuji, S.,Ikeda, Y.,Terakawa, J.,Sasaki, M.,Yoshino, H.,Majd, N.,Zheng, Y.,Kahoud, E.R.,Yokota, T.,Emerling, B.M.,Asara, J.M.,Ishida, T.,Locasale, J.W.,Daikoku, T.,Anastasiou, D.,Senda, T.,Sasaki, A.T.
The Lipid Kinase PI5P4K beta Is an Intracellular GTP Sensor for Metabolism and Tumorigenesis
Mol.Cell, 61:187-198, 2016
Cited by
PubMed: 26774281
DOI: 10.1016/j.molcel.2015.12.011
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.6 Å)
Structure validation

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