PDB: 36840 件ウェブページステータス検索Chemie searchBIRD

---

5L1Q	X-ray Structure of Cytochrome P450 PntM with Dihydropentalenolactone F 分子名称: Dihydropentalenolactone F, PROTOPORPHYRIN IX CONTAINING FE, Pentalenolactone synthase 著者 Duan, L, Jogl, G, Cane, D.E. 登録日 2016-07-29 公開日 2016-09-14 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 The Cytochrome P450-Catalyzed Oxidative Rearrangement in the Final Step of Pentalenolactone Biosynthesis: Substrate Structure Determines Mechanism. J.Am.Chem.Soc., 138, 2016
5HR2	Crystal structure of thioredoxin L94A mutant 分子名称: COPPER (II) ION, Thioredoxin 著者 Noguera, M.E, Vazquez, D.S, Howard, E.I, Cousido-Siah, A, Mitschler, A, Podjarny, A, Santos, J. 登録日 2016-01-22 公開日 2017-02-22 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Structural variability of E. coli thioredoxin captured in the crystal structures of single-point mutants. Sci Rep, 7, 2017
5HNV	Crystal structure of PpkA 分子名称: ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... 著者 Li, P.P, Ran, T.T, Wang, W.W. 登録日 2016-01-19 公開日 2017-01-25 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.41 Å) 主引用文献 Crystal structures of the kinase domain of PpkA, a key regulatory component of T6SS, reveal a general inhibitory mechanism. Biochem.J., 475, 2018
8D40	Crystal structure of human CELSR1 EC1-4 分子名称: CALCIUM ION, Cadherin EGF LAG seven-pass G-type receptor 1, SODIUM ION 著者 Tamilselvan, E, Sotomayor, M. 登録日 2022-06-01 公開日 2023-08-30 実験手法 X-RAY DIFFRACTION (3.554 Å) 主引用文献 Crystal structure of human CELSR1 EC1-4 to be published
5HQ1	Comment on S. W. M. Tanley and J. R. Helliwell Structural dynamics of cisplatin binding to histidine in a protein Struct. Dyn. 1, 034701 (2014) regarding the refinement of 4mwk, 4mwm, 4mwn and 4oxe and the method we have adopted. 分子名称: CHLORIDE ION, DIMETHYL SULFOXIDE, Lysozyme C, ... 著者 Helliwell, J.R. 登録日 2016-01-21 公開日 2016-05-18 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1 Å) 主引用文献 Comment on "Structural dynamics of cisplatin binding to histidine in a protein" [Struct. Dyn. 1, 034701 (2014)]. Struct Dyn, 3, 2016
7QWN	Crystal structure of CYP125 from Mycobacterium tuberculosis in complex with an inhibitor 分子名称: CHLORIDE ION, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, ... 著者 Snee, M, Katariya, M, Levy, C, Leys, D. 登録日 2022-01-25 公開日 2023-02-01 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Structure Based Discovery of Inhibitors of CYP125 and CYP142 from Mycobacterium tuberculosis. Chemistry, 29, 2023
5HQI	Insulin with proline analog HzP at position B28 in the T2 state 分子名称: Insulin A-Chain, Insulin B-Chain 著者 Lieblich, S.A, Fang, K.Y, Cahn, J.K.B, Tirrell, D.A. 登録日 2016-01-21 公開日 2017-01-25 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (0.97 Å) 主引用文献 4S-Hydroxylation of Insulin at ProB28 Accelerates Hexamer Dissociation and Delays Fibrillation. J. Am. Chem. Soc., 139, 2017
8SBI	Crystal structure of human sterol 14 alpha-demethylase (CYP51) in the ligand-free state 分子名称: Lanosterol 14-alpha demethylase, PROTOPORPHYRIN IX CONTAINING FE 著者 Hargrove, T.Y, Wawrzak, Z, Lepesheva, G.I. 登録日 2023-04-03 公開日 2023-04-12 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.73 Å) 主引用文献 Structural dynamics of sterol 14 alpha demethylases upon catalysis To Be Published
5HYU	Structure of human C4b-binding protein alpha chain CCP domains 1 and 2 in complex with the hypervariable region of group A Streptococcus M2 protein 分子名称: C4b-binding protein alpha chain, M protein, serotype 2.1 著者 Buffalo, C.Z, Bahn-Suh, A.J, Ghosh, P. 登録日 2016-02-01 公開日 2016-07-20 最終更新日 2019-12-11 実験手法 X-RAY DIFFRACTION (2.561 Å) 主引用文献 Conserved patterns hidden within group A Streptococcus M protein hypervariability recognize human C4b-binding protein. Nat Microbiol, 1, 2016
5KT1	The crystal structure of 4-methylthiobenzoate-bound CYP199A4 分子名称: 4-methylsulfanylbenzoic acid, CHLORIDE ION, Cytochrome P450, ... 著者 Coleman, T, Bruning, J.B, Bell, S.G. 登録日 2016-07-11 公開日 2018-01-17 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.015 Å) 主引用文献 The crystal structure of 4-methylthiobenzoate-bound CYP199A4 To Be Published
5F8U	Ligand occupancy in crystal structure of beta1-adrenergic receptor previously submitted by Huang et al 分子名称: 4-{[(2S)-3-(tert-butylamino)-2-hydroxypropyl]oxy}-3H-indole-2-carbonitrile, Beta-1 adrenergic receptor 著者 Leslie, A.G.W, Warne, A, Tate, C.G. 登録日 2015-12-09 公開日 2015-12-23 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.35 Å) 主引用文献 Ligand occupancy in crystal structure of Beta1 adrenergic G protein coupled receptor Nat.Struct.Mol.Biol., 22, 2015
5KJZ	Co-crystal structure of PKA RI alpha CNB-B mutant (G316R/A336T) with cGMP 分子名称: CYCLIC GUANOSINE MONOPHOSPHATE, GLYCEROL, cAMP-dependent protein kinase type I-alpha regulatory subunit 著者 Lorenz, R, Moon, E, Kim, J.J, Huang, G.Y, Kim, C, Herberg, F.W. 登録日 2016-06-20 公開日 2017-06-28 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.347 Å) 主引用文献 Mutations of PKA cyclic nucleotide-binding domains reveal novel aspects of cyclic nucleotide selectivity. Biochem. J., 474, 2017
5F8T	The crystal structure of human Plasma Kallikrein in complex with its peptide inhibitor pkalin-2 分子名称: CYS-PRO-LYS-ARG-PHE-M70-ALA-LEU-PHE-CYS, Plasma kallikrein light chain, SULFATE ION, ... 著者 Xu, M, Jiang, L, Xu, P, Luo, Z, Andreasen, P, Huang, M. 登録日 2015-12-09 公開日 2016-12-14 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 The crystal structure of human Plasma Kallikrein in complex with its peptide inhibitor pkalin-2 To Be Published
5KZI	Crystal structure of human Pim-1 kinase in complex with an imidazopyridazine inhibitor. 分子名称: Serine/threonine-protein kinase pim-1, ~{N}-[4-[(3~{S})-3-azanylpiperidin-1-yl]pyridin-3-yl]-2-[2,6-bis(fluoranyl)phenyl]imidazo[1,5-b]pyridazin-7-amine 著者 Mohr, C. 登録日 2016-07-25 公開日 2016-11-09 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Discovery of imidazopyridazines as potent Pim-1/2 kinase inhibitors. Bioorg. Med. Chem. Lett., 26, 2016
5FEL	Hen egg lysozyme at room temperature solved from dataset acquired by oscillation method 分子名称: CHLORIDE ION, Lysozyme C, SODIUM ION 著者 Tsujino, S, Tomizaki, T. 登録日 2015-12-17 公開日 2016-05-25 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Ultrasonic acoustic levitation for fast frame rate X-ray protein crystallography at room temperature. Sci Rep, 6, 2016
7QAB	NMR Solution Structure of mussel adhesive protein Pvfp-5b 分子名称: PVFP-5 著者 Morando, M.A, Venturella, F, Pastore, A, Alfano, C. 登録日 2021-11-16 公開日 2022-08-03 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Solution structure of recombinant Pvfp-5 beta reveals insights into mussel adhesion. Commun Biol, 5, 2022
8SDK	The MicroED structure of proteinase K crystallized by suspended drop crystallization 分子名称: CALCIUM ION, Proteinase K, SULFATE ION 著者 Gillman, C, Nicolas, W.J, Martynowycz, M.W, Gonen, T. 登録日 2023-04-06 公開日 2023-05-31 最終更新日 2023-07-12 実験手法 ELECTRON CRYSTALLOGRAPHY (2.1 Å) 主引用文献 Design and implementation of suspended drop crystallization. Iucrj, 10, 2023
7QAJ	ZK002 with Anti-angiogenic and Anti-inflamamtory Properties 分子名称: SULFATE ION, Snaclec clone 2100755 alpha, Snaclec clone 2100755 beta 著者 Wong, W.Y, Chan, B.D, Muk Lan Lee, M, Dai, X, Tsim, K.W.K, Hsiao, W.L.W, Li, M, Li, X.Y, Tai, W.C.S. 登録日 2021-11-17 公開日 2023-06-14 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Isolation and characterization of ZK002, a novel dual function snake venom protein from Deinagkistrodon acutus with anti-angiogenic and anti-inflammatory properties. Front Pharmacol, 14, 2023
5L1S	X-ray Structure of F232L mutant of Cytochrome P450 PntM with pentalenolactone F 分子名称: PROTOPORPHYRIN IX CONTAINING FE, Pentalenolactone synthase, pentalenolactone F 著者 Duan, L, Jogl, G, Cane, D.E. 登録日 2016-07-29 公開日 2016-09-14 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 The Cytochrome P450-Catalyzed Oxidative Rearrangement in the Final Step of Pentalenolactone Biosynthesis: Substrate Structure Determines Mechanism. J.Am.Chem.Soc., 138, 2016
5L2S	The X-ray co-crystal structure of human CDK6 and Abemaciclib. 分子名称: Cyclin-dependent kinase 6, N-{5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl}-5-fluoro-4-[4-fluoro-2-methyl-1-(propan-2-yl)-1H-benzimidazol-6-yl]py rimidin-2-amine 著者 Chen, P, Ferre, R.A, Deihl, W, Yu, X, He, Y.-A. 登録日 2016-08-02 公開日 2016-08-24 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Spectrum and Degree of CDK Drug Interactions Predicts Clinical Performance. Mol.Cancer Ther., 15, 2016
7QAC	The T2 structure of polycrystalline cubic human insulin 分子名称: Insulin A chain, Insulin B chain 著者 Karavassili, F, Triandafillidis, D.P, Valmas, A, Spiliopoulou, M, Fili, S, Kontou, P, Bowler, M.W, Von Dreele, R.B, Fitch, A, Margiolaki, I. 登録日 2021-11-16 公開日 2023-06-21 最終更新日 2024-02-07 実験手法 POWDER DIFFRACTION (2.29 Å) 主引用文献 The T 2 structure of polycrystalline cubic human insulin. Acta Crystallogr D Struct Biol, 79, 2023
5KQX	Protease E35D-SQV 分子名称: (2S)-N-[(2S,3R)-4-[(2S,3S,4aS,8aS)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-3-hydroxy-1 -phenyl-butan-2-yl]-2-(quinolin-2-ylcarbonylamino)butanediamide, Protease E35D-SQV 著者 Liu, Z, Poole, K.M, Mahon, B.P, McKenna, R, Fanucci, G.E. 登録日 2016-07-06 公開日 2016-09-21 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Effects of Hinge-region Natural Polymorphisms on Human Immunodeficiency Virus-Type 1 Protease Structure, Dynamics, and Drug Pressure Evolution. J.Biol.Chem., 291, 2016
5FM4	Structure of the C-terminally extended domain My4 of human myomesin (space group P21) 分子名称: MYOMESIN-1 著者 Pernigo, S, Steiner, R.A. 登録日 2015-10-30 公開日 2016-11-23 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Binding of Myomesin to Obscurin-Like-1 at the Muscle M-Band Provides a Strategy for Isoform-Specific Mechanical Protection. Structure, 25, 2017
5L17	The crystal structure of neuraminidase in complex with zanamivir from A/Shanghai/2/2013 (H7N9) influenza virus 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neuraminidase, ... 著者 Yang, H, Stevens, J. 登録日 2016-07-28 公開日 2017-08-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Drug Susceptibility Evaluation of an Influenza A(H7N9) Virus by Analyzing Recombinant Neuraminidase Proteins. J. Infect. Dis., 216, 2017
5L1W	X-ray Structure of 2-Mercaptoethanol modified M81C mutant of Cytochrome P450 PntM with pentalenolactone F 分子名称: PROTOPORPHYRIN IX CONTAINING FE, Pentalenolactone synthase, pentalenolactone F 著者 Duan, L, Jogl, G, Cane, D.E. 登録日 2016-07-29 公開日 2016-09-14 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 The Cytochrome P450-Catalyzed Oxidative Rearrangement in the Final Step of Pentalenolactone Biosynthesis: Substrate Structure Determines Mechanism. J.Am.Chem.Soc., 138, 2016

<106107108109110111112113114115116117118119120121>