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4HRH
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Crystal Structure of p11-Annexin A2(N-terminal) Fusion Protein in Complex with SMARCA3 Peptide
分子名称: Helicase-like transcription factor, Protein S100-A10, Annexin A2, ...
著者Gao, P, Patel, D.J.
登録日2012-10-27
公開日2013-03-06
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.001 Å)
主引用文献SMARCA3, a Chromatin-Remodeling Factor, Is Required for p11-Dependent Antidepressant Action.
Cell(Cambridge,Mass.), 152, 2013
2CKL
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Ring1b-Bmi1 E3 catalytic domain structure
分子名称: IODIDE ION, POLYCOMB GROUP RING FINGER PROTEIN 4, UBIQUITIN LIGASE PROTEIN RING2, ...
著者Buchwald, G, van der Stoop, P, Weichenrieder, O, Perrakis, A, van Lohuizen, M, Sixma, T.K.
登録日2006-04-20
公開日2006-05-11
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure and E3-Ligase Activity of the Ring-Ring Complex of Polycomb Proteins Bmi1 and Ring1B.
Embo J., 25, 2006
4KWH
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The crystal structure of angucycline C-6 ketoreductase LanV with bound NADP
分子名称: ACETIC ACID, DI(HYDROXYETHYL)ETHER, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Paananen, P, Patrikainen, P, Kallio, P, Mantsala, P, Niemi, J, Niiranen, L, Metsa-Ketela, M.
登録日2013-05-24
公開日2013-07-31
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural and functional analysis of angucycline C-6 ketoreductase LanV involved in landomycin biosynthesis.
Biochemistry, 52, 2013
4L0F
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Structure of P450sky (CYP163B3), a cytochrome P450 from skyllamycin biosynthesis (open active site)
分子名称: 1,2-ETHANEDIOL, P450 monooxygenase, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Cryle, M.J.
登録日2013-05-31
公開日2013-09-25
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Cytochrome p450sky interacts directly with the nonribosomal Peptide synthetase to generate three amino Acid precursors in skyllamycin biosynthesis.
Acs Chem.Biol., 8, 2013
4L79
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Crystal Structure of nucleotide-free Myosin 1b residues 1-728 with bound Calmodulin
分子名称: Calmodulin, MAGNESIUM ION, Unconventional myosin-Ib
著者Shuman, H, Zwolak, A, Dominguez, R, Ostap, E.M.
登録日2013-06-13
公開日2014-01-29
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A vertebrate myosin-I structure reveals unique insights into myosin mechanochemical tuning.
Proc.Natl.Acad.Sci.USA, 111, 2014
4IA3
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BU of 4ia3 by Molmil
Diastereotopic and Deuterium Effects in Gemini
分子名称: 21-NOR-9,10-SECOCHOLESTA-5,7,10(19)-TRIENE-1,3,25-TRIOL, 20-(4-HYDROXY-4-METHYLPENTYL)-, (1A,3B,5Z,7E), ...
著者Maehr, H, Rochel, N, Suh, N, Uskokovic, M.
登録日2012-12-06
公開日2013-04-24
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Diastereotopic and deuterium effects in gemini.
J.Med.Chem., 56, 2013
2B5I
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BU of 2b5i by Molmil
cytokine receptor complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cytokine receptor common gamma chain, ...
著者Wang, X, Rickert, M, Garcia, K.C.
登録日2005-09-28
公開日2005-11-29
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of the quaternary complex of interleukin-2 with its alpha, beta, and gammac receptors.
Science, 310, 2005
4I4E
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Structure of Focal Adhesion Kinase catalytic domain in complex with hinge binding pyrazolobenzothiazine compound.
分子名称: Focal adhesion kinase 1, [4-(2-hydroxyethyl)piperidin-1-yl][4-(5-methyl-4,4-dioxido-1,5-dihydropyrazolo[4,3-c][2,1]benzothiazin-8-yl)phenyl]methanone
著者Skene, R.J, Hosfield, D.J.
登録日2012-11-27
公開日2013-03-06
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structure-based discovery of cellular-active allosteric inhibitors of FAK.
Bioorg.Med.Chem.Lett., 23, 2013
2AN9
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Crystal Structure Of Oligomeric E.coli Guanylate Kinase In Complex With GDP
分子名称: GUANOSINE, GUANOSINE-5'-DIPHOSPHATE, Guanylate kinase, ...
著者Hible, G, Renault, L, Schaeffer, F, Christova, P, Radulescu, A.Z, Evrin, C, Gilles, A.M, Cherfils, J.
登録日2005-08-11
公開日2005-08-30
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Calorimetric and crystallographic analysis of the oligomeric structure of Escherichia coli GMP kinase
J.Mol.Biol., 352, 2005
4LK1
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Crystal Structure Analysis of the E.coli holoenzyme
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Bae, B, Darst, S.A.
登録日2013-07-05
公開日2013-11-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.8369 Å)
主引用文献Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of sigma 70 domain 1.1.
Proc.Natl.Acad.Sci.USA, 110, 2013
4KXJ
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BU of 4kxj by Molmil
Crystal structure of HCoV-OC43 N-NTD complexed with PJ34
分子名称: Nucleoprotein, N~2~,N~2~-DIMETHYL-N~1~-(6-OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)GLYCINAMIDE
著者Lin, S.Y, Hou, M.H.
登録日2013-05-27
公開日2014-05-28
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structural basis for the identification of the N-terminal domain of coronavirus nucleocapsid protein as an antiviral target
J.Med.Chem., 57, 2014
4KUM
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BU of 4kum by Molmil
Structure of LSD1-CoREST-Tetrahydrofolate complex
分子名称: (6S)-5,6,7,8-TETRAHYDROFOLATE, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Luka, Z, Pakhomova, S, Loukachevitch, L.V, Calcutt, M.W, Newcomer, M.E, Wagner, C.
登録日2013-05-22
公開日2014-05-07
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Crystal structure of the histone lysine specific demethylase LSD1 complexed with tetrahydrofolate.
Protein Sci., 23, 2014
4L0E
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Structure of P450sky (CYP163B3), a cytochrome P450 from skyllamycin biosynthesis (heme-coordinated expression tag)
分子名称: P450 monooxygenase, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION
著者Cryle, M.J.
登録日2013-05-31
公開日2013-09-25
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Cytochrome p450sky interacts directly with the nonribosomal Peptide synthetase to generate three amino Acid precursors in skyllamycin biosynthesis.
Acs Chem.Biol., 8, 2013
2B8K
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12-subunit RNA Polymerase II
分子名称: DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 140 kDa polypeptide, DNA-directed RNA polymerase II 19 kDa polypeptide, ...
著者Meyer, P.A, Ye, P, Zhang, M, Suh, M.H, Fu, J.
登録日2005-10-07
公開日2006-06-20
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (4.15 Å)
主引用文献Phasing RNA Polymerase II Using Intrinsically Bound Zn Atoms: An Updated Structural Model.
Structure, 14, 2006
4L7E
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Three dimensional structure of mutant D78A of human HD domain-containing protein 2, Genomics Consortium (NESG) Target HR6723
分子名称: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, HD domain-containing protein 2, ...
著者Kuzin, A, Su, M, Yakunin, A, Beloglazova, N, Seetharaman, J, Maglaqui, M, Xiao, R, Lee, D, Brown, G, Flick, R, Everett, J.K, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
登録日2013-06-13
公開日2013-07-24
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.229 Å)
主引用文献Northeast Structural Genomics Consortium Target HR6723
To be Published
4KWI
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BU of 4kwi by Molmil
The crystal structure of angucycline C-6 ketoreductase LanV with bound NADP and 11-deoxy-6-oxylandomycinone
分子名称: 1,8-dihydroxy-3-methyltetraphene-6,7,12(5H)-trione, DI(HYDROXYETHYL)ETHER, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Paananen, P, Patrikainen, P, Mantsala, P, Niemi, J, Niiranen, L, Metsa-Ketela, M.
登録日2013-05-24
公開日2013-07-31
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural and functional analysis of angucycline C-6 ketoreductase LanV involved in landomycin biosynthesis.
Biochemistry, 52, 2013
4L3T
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Crystal Structure of Substrate-free Human Presequence Protease
分子名称: ACETATE ION, GLYCEROL, Presequence protease, ...
著者King, J.V, Liang, W.G, Tang, W.J.
登録日2013-06-06
公開日2013-07-03
最終更新日2025-03-26
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Molecular basis of substrate recognition and degradation by human presequence protease.
Structure, 22, 2014
2CN0
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Complex of Recombinant Human Thrombin with a Designed Inhibitor
分子名称: 4-(1R,3AS,4R,8AS,8BR)-[1-DIFLUOROMETHYL-2-(4-FLUOROBENZYL)-3-OXODECAHYDROPYRROLO[3,4-A]PYRROLIZIN-4-YL]BENZAMIDINE, CALCIUM ION, HIRUDIN IIA, ...
著者Hoffmann-Roder, A, Schweizer, E, Egger, J, Seiler, P, Obst-Sander, U, Wagner, B, Kansy, M, Banner, D.W, Diederich, F.
登録日2006-05-17
公開日2006-11-06
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Mapping the Fluorophilicity of a Hydrophobic Pocket: Synthesis and Biological Evaluation of Tricyclic Thrombin Inhibitors Directing Fluorinated Alkyl Groups Into the P Pocket
Chemmedchem, 1, 2006
4KVK
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Crystal structure of Oryza sativa fatty acid alpha-dioxygenase
分子名称: CALCIUM ION, CHLORIDE ION, DECYL-BETA-D-MALTOPYRANOSIDE, ...
著者Zhu, G, Koszelak-Rosenblum, M, Malkowski, M.G.
登録日2013-05-22
公開日2013-08-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Crystal structures of alpha-dioxygenase from Oryza sativa: Insights into substrate binding and activation by hydrogen peroxide.
Protein Sci., 22, 2013
2CTI
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BU of 2cti by Molmil
DETERMINATION OF THE COMPLETE THREE-DIMENSIONAL STRUCTURE OF THE TRYPSIN INHIBITOR FROM SQUASH SEEDS IN AQUEOUS SOLUTION BY NUCLEAR MAGNETIC RESONANCE AND A COMBINATION OF DISTANCE GEOMETRY AND DYNAMICAL SIMULATED ANNEALING
分子名称: TRYPSIN INHIBITOR
著者Holak, T.A, Gondol, D, Otlewski, J, Wilusz, T.
登録日1990-08-28
公開日1992-01-15
最終更新日2024-10-30
実験手法SOLUTION NMR
主引用文献Determination of the complete three-dimensional structure of the trypsin inhibitor from squash seeds in aqueous solution by nuclear magnetic resonance and a combination of distance geometry and dynamical simulated annealing.
J.Mol.Biol., 210, 1989
2CTM
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BU of 2ctm by Molmil
Solution structure of the 14th KH type I domain from human Vigilin
分子名称: Vigilin
著者Tomizawa, T, Kigawa, T, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-05-24
公開日2005-11-24
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the 14th KH type I domain from human Vigilin
To be Published
2CTE
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Solution structure of the 1st KH type I domain from human Vigilin
分子名称: Vigilin
著者Tomizawa, T, Kigawa, T, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-05-24
公開日2005-11-24
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the 1st KH type I domain from human Vigilin
To be Published
2CQ3
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solution structure of RNA binding domain in RNA binding motif protein 9
分子名称: RNA-binding protein 9
著者Tsuda, K, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-05-19
公開日2005-11-19
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献solution structure of RNA binding domain in RNA binding motif protein 9
To be Published
2CQN
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Solution structure of the FF domain of human Formin-binding protein 3
分子名称: Formin-binding protein 3
著者Suzuki, S, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-05-20
公開日2005-11-20
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the FF domain of human Formin-binding protein 3
To be Published
4LB5
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Crystal structure of PKZ Zalpha in complex with ds(CG)6 (hexagonal form)
分子名称: 5'-D(*TP*CP*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*G)-3', ACETATE ION, Protein kinase containing Z-DNA binding domains
著者De Rosa, M, Zacarias, S, Athanasiadis, A.
登録日2013-06-20
公開日2013-09-18
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for Z-DNA binding and stabilization by the zebrafish Z-DNA dependent protein kinase PKZ.
Nucleic Acids Res., 41, 2013

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件を2025-07-09に公開中

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