4L7E

Three dimensional structure of mutant D78A of human HD domain-containing protein 2, Genomics Consortium (NESG) Target HR6723

Summary for 4L7E

Related4DMB
DescriptorHD domain-containing protein 2, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... (5 entities in total)
Functional Keywordsstructural genomics, psi-biology, protein structure initiative, northeast structural genomics consortium, nesg, hdcc2 mutant d78a, signaling protein
Biological sourceHomo sapiens (human)
Total number of polymer chains2
Total molecular weight48589.17
Authors
Primary citation
Kuzin, A.,Su, M.,Yakunin, A.,Beloglazova, N.,Seetharaman, J.,Maglaqui, M.,Xiao, R.,Lee, D.,Brown, G.,Flick, R.,Everett, J.K.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L.,Northeast Structural Genomics Consortium (NESG)
Northeast Structural Genomics Consortium Target HR6723
To be Published,
Experimental method
X-RAY DIFFRACTION (2.229 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.213502.1%1.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 4l7e
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Molmil generated image of 4l7e
rotated about x axis by 90°
Molmil generated image of 4l7e
rotated about y axis by 90°