4IA3

Diastereotopic and Deuterium Effects in Gemini

Summary for 4IA3

• Entry DOI: 10.2210/pdb4ia3/pdb
• Related: 2HCD 3O1D 3O1E 4IA1 4IA2 4IA7
• Descriptor: Vitamin D3 receptor A, Nuclear receptor coactivator 2, 21-NOR-9,10-SECOCHOLESTA-5,7,10(19)-TRIENE-1,3,25-TRIOL, 20-(4-HYDROXY-4-METHYLPENTYL)-, (1A,3B,5Z,7E), ... (4 entities in total)
• Functional Keywords: vdr-agonist complex, alpha helical sandwich, transcription regulation, dna, rxr, phosphorylation, nucleus, transcription-transcription activator complex, transcription/transcription activator
• Biological source: Danio rerio (leopard danio,zebra danio,zebra fish); More
• Cellular location: Nucleus: Q9PTN2 Q15596
• Total number of polymer chains: 2
• Total formula weight: 35999.18

Authors

Maehr, H.,Rochel, N.,Suh, N.,Uskokovic, M. (deposition date: 2012-12-06, release date: 2013-04-24, Last modification date: 2024-02-28)

• Primary citation: Maehr, H.,Rochel, N.,Lee, H.J.,Suh, N.,Uskokovic, M.R.; Diastereotopic and deuterium effects in gemini.; J.Med.Chem., 56:3878-3888, 2013; PubMed: 23566225; DOI: 10.1021/jm400032t

Experimental method

X-RAY DIFFRACTION (2.7 Å)