Crystal Structure Analysis of the E.coli holoenzyme

Summary for 4LK1

DescriptorDNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... (7 entities in total)
Functional Keywordstransferase
Biological sourceEscherichia coli
Cellular locationCytoplasm (Potential) P00579
Total number of polymer chains12
Total molecular weight879725.64
Bae, B.,Darst, S.A. (deposition date: 2013-07-05, release date: 2013-11-13, Last modification date: 2013-12-18)
Primary citation
Bae, B.,Davis, E.,Brown, D.,Campbell, E.A.,Wigneshweraraj, S.,Darst, S.A.
Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of sigma 70 domain 1.1.
Proc.Natl.Acad.Sci.USA, 110:19772-19777, 2013
PubMed: 24218560 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.1314576110
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.27412 0.3% 8.4% 4.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-11-18