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2WPM
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factor IXa superactive mutant, EGR-CMK inhibited
分子名称: CALCIUM ION, COAGULATION FACTOR IXA HEAVY CHAIN, COAGULATION FACTOR IXA LIGHT CHAIN, ...
著者Zogg, T, Brandstetter, H.
登録日2009-08-06
公開日2009-12-22
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Basis of the Cofactor- and Substrate-Assisted Activation of Human Coagulation Factor Ixa
Structure, 17, 2009
5X8Q
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Crystal Structure of the mutant Human ROR gamma Ligand Binding Domain With rockogenin.
分子名称: (1R,2S,4S,5'R,6R,7S,8R,9S,10R,12S,13S,16S,18S)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icosane-6,2'-oxane]-10,16-diol, Nuclear receptor ROR-gamma, Nuclear receptor corepressor 2
著者Noguchi, M, Nomura, A, Murase, K, Doi, S, Yamaguchi, K, Adachi, T.
登録日2017-03-03
公開日2017-06-07
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Ternary complex of human ROR gamma ligand-binding domain, inverse agonist and SMRT peptide shows a unique mechanism of corepressor recruitment
Genes Cells, 22, 2017
1MWL
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Crystal structure of geneticin bound to the eubacterial 16S rRNA A site
分子名称: 5'-R(*CP*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*C)-3', GENETICIN
著者Vicens, Q, Westhof, E.
登録日2002-09-30
公開日2003-02-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of geneticin bound to a bacterial 16S ribosomal RNA A site oligonucleotide
J.Mol.Biol., 326, 2003
4WF9
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The crystal structure of the large ribosomal subunit of Staphylococcus aureus in complex with telithromycin
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 23S ribosomal RNA, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
著者Eyal, Z, Matzov, D, Krupkin, M, Wekselman, I, Zimmerman, E, Rozenberg, H, Bashan, A, Yonath, A.E.
登録日2014-09-14
公開日2015-10-21
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.427 Å)
主引用文献Structural insights into species-specific features of the ribosome from the pathogen Staphylococcus aureus.
Proc.Natl.Acad.Sci.USA, 112, 2015
1MWH
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BU of 1mwh by Molmil
REOVIRUS POLYMERASE LAMBDA3 BOUND TO MRNA CAP ANALOG
分子名称: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, MANGANESE (II) ION, MINOR CORE PROTEIN LAMBDA 3
著者Tao, Y, Farsetta, D.L, Nibert, M.L, Harrison, S.C.
登録日2002-09-29
公開日2002-12-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献RNA Synthesis in a Cage-Structural Studies of Reovirus Polymerase lambda3
Cell(Cambridge,Mass.), 111, 2002
1N38
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reovirus polymerase lambda3 elongation complex with one phosphodiester bond formed
分子名称: 3'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE, 3'-DEOXY-URIDINE 5'-TRIPHOSPHATE, 5'-R(*AP*UP*UP*AP*GP*C)-3', ...
著者Tao, Y, Farsetta, D.L, Nibert, M.L, Harrison, S.C.
登録日2002-10-25
公開日2002-12-25
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献RNA Synthesis in a Cage--Structural Studies of Reovirus Polymerase [lambda] 3
Cell(Cambridge,Mass.), 111, 2002
5U41
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Human PPARdelta ligand-binding domain in complexed with specific agonist 16
分子名称: 6-[2-({benzyl[4-(thiophen-3-yl)benzene-1-carbonyl]amino}methyl)phenoxy]hexanoic acid, DI(HYDROXYETHYL)ETHER, POTASSIUM ION, ...
著者Wu, C.-C, Baiga, T.J, Downes, M, La Clair, J.J, Atkins, A.R, Richard, S.B, Stockley-Noel, T.A, Bowman, M.E, Evans, R.M, Noel, J.P.
登録日2016-12-03
公開日2017-03-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for specific ligation of the peroxisome proliferator-activated receptor delta.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
4WVF
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Crystal structure of KPT276 in complex with CRM1-Ran-RanBP1
分子名称: (2E)-3-{3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl}-1-(3,3-difluoroazetidin-1-yl)prop-2-en-1-one, 1,2-ETHANEDIOL, CHLORIDE ION, ...
著者Sun, Q, Chook, Y.
登録日2014-11-05
公開日2015-07-15
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Nuclear export inhibitors avert progression in preclinical models of inflammatory demyelination.
Nat.Neurosci., 18, 2015
1MZP
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Structure of the L1 protuberance in the ribosome
分子名称: 50s ribosomal protein L1P, MAGNESIUM ION, fragment of 23S rRNA
著者Nikulin, A, Eliseikina, I, Tishchenko, S, Nevskaya, N, Davydova, N, Platonova, O, Piendl, W, Selmer, M, Liljas, A, Zimmermann, R, Garber, M, Nikonov, S.
登録日2002-10-09
公開日2003-01-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structure of the L1 protuberance in the ribosome.
Nat.Struct.Biol., 10, 2003
1N00
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Annexin Gh1 from cotton
分子名称: SULFATE ION, annexin Gh1
著者Hofmann, A, Delmer, D.P, Wlodawer, A.
登録日2002-10-10
公開日2003-06-24
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The crystal structure of annexin Gh1 from Gossypium hirsutum reveals an unusual S3 cluster.
Eur.J.Biochem., 270, 2003
2R2V
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Sequence Determinants of the Topology of the Lac Repressor Tetrameric Coiled Coil
分子名称: ACETATE ION, CITRIC ACID, GCN4 leucine zipper, ...
著者Liu, J, Lu, M.
登録日2007-08-27
公開日2008-06-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Conformational specificity of the lac repressor coiled-coil tetramerization domain.
Biochemistry, 46, 2007
5U3R
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BU of 5u3r by Molmil
Human PPARdelta ligand-binding domain in complexed with specific agonist 2
分子名称: 6-[2-({[4-(furan-2-yl)benzene-1-carbonyl](propan-2-yl)amino}methyl)phenoxy]hexanoic acid, DI(HYDROXYETHYL)ETHER, Peroxisome proliferator-activated receptor delta, ...
著者Wu, C.-C, Baiga, T.J, Downes, M, La Clair, J.J, Atkins, A.R, Richard, S.B, Stockley-Noel, T.A, Bowman, M.E, Evans, R.M, Noel, J.P.
登録日2016-12-03
公開日2017-03-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural basis for specific ligation of the peroxisome proliferator-activated receptor delta.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5U43
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Human PPARdelta ligand-binding domain in complexed with specific agonist 12
分子名称: 6-(2-{[cyclopropyl(4'-methoxy[1,1'-biphenyl]-4-carbonyl)amino]methyl}phenoxy)hexanoic acid, DI(HYDROXYETHYL)ETHER, Peroxisome proliferator-activated receptor delta, ...
著者Wu, C.-C, Baiga, T.J, Downes, M, La Clair, J.J, Atkins, A.R, Richard, S.B, Stockley-Noel, T.A, Bowman, M.E, Evans, R.M, Noel, J.P.
登録日2016-12-03
公開日2017-03-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for specific ligation of the peroxisome proliferator-activated receptor delta.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
8GP6
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Structure of the vaccinia virus A16/G9 sub-complex from the orthopoxvirus entry-fusion complex
分子名称: GLYCEROL, Myristoylated protein G9, Virion membrane protein A16
著者Lu, G.W, Yang, F.L, Lin, S.
登録日2022-08-25
公開日2023-05-17
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis of poxvirus A16/G9 binding for sub-complex formation.
Emerg Microbes Infect, 12, 2023
4WMW
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The structure of MBP-MCL1 bound to ligand 5 at 1.9A
分子名称: 1,2-ETHANEDIOL, 2-hydroxy-5-(methylsulfanyl)benzoic acid, FORMIC ACID, ...
著者Clifton, M.C, Dranow, D.M.
登録日2014-10-09
公開日2015-05-06
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A Maltose-Binding Protein Fusion Construct Yields a Robust Crystallography Platform for MCL1.
Plos One, 10, 2015
2YHV
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Structure of L1196M Mutant Anaplastic Lymphoma Kinase
分子名称: ALK TYROSINE KINASE RECEPTOR
著者McTigue, M, Deng, Y, Liu, W, Brooun, A.
登録日2011-05-06
公開日2011-05-18
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Design of Potent and Selective Inhibitors to Overcome Clinical Anaplastic Lymphoma Kinase Mutations Resistant to Crizotinib.
J.Med.Chem., 57, 2014
4WQL
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Crystal structure of aminoglycoside nucleotidylyltransferase ANT(2")-Ia, kanamycin-bound
分子名称: 2''-aminoglycoside nucleotidyltransferase, GLYCEROL, ISOPROPYL ALCOHOL, ...
著者Cox, G, Stogios, P.J, Savchenko, A, Wright, G.D, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2014-10-22
公開日2014-11-12
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Structural and Molecular Basis for Resistance to Aminoglycoside Antibiotics by the Adenylyltransferase ANT(2)-Ia.
Mbio, 6, 2015
5U3Y
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BU of 5u3y by Molmil
Human PPARdelta ligand-binding domain in complexed with specific agonist 9
分子名称: 6-[2-({cyclopropyl[4-(furan-2-yl)benzene-1-carbonyl]amino}methyl)phenoxy]hexanoic acid, DI(HYDROXYETHYL)ETHER, Peroxisome proliferator-activated receptor delta, ...
著者Wu, C.-C, Baiga, T.J, Downes, M, La Clair, J.J, Atkins, A.R, Richard, S.B, Stockley-Noel, T.A, Bowman, M.E, Evans, R.M, Noel, J.P.
登録日2016-12-03
公開日2017-03-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for specific ligation of the peroxisome proliferator-activated receptor delta.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5U3Q
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Human PPARdelta ligand-binding domain in complexed with specific agonist 1
分子名称: 6-(2-{[([1,1'-biphenyl]-4-carbonyl)(propan-2-yl)amino]methyl}phenoxy)hexanoic acid, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Wu, C.-C, Baiga, T.J, Downes, M, La Clair, J.J, Atkins, A.R, Richard, S.B, Stockley-Noel, T.A, Bowman, M.E, Evans, R.M, Noel, J.P.
登録日2016-12-03
公開日2017-03-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural basis for specific ligation of the peroxisome proliferator-activated receptor delta.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
4XTK
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Structure of TM1797, a CAS1 protein from Thermotoga maritima
分子名称: CRISPR-associated endonuclease Cas1
著者Petit, P, Beloglazova, N, Skarina, T, Chang, C, Edwards, A, Joachimiak, A, Savchenko, A, Midwest Center for Structural Genomics (MCSG)
登録日2015-01-23
公開日2015-02-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure and nuclease activity of tm1797, a cas1 protein from thermotoga maritima
To Be Published
4XVN
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Crystal structure of the small terminase from thermophilic phage G20C
分子名称: Small terminase
著者Loredo-Varela, J, Jenkins, H.T, Chechik, M, Greive, S.J, Antson, A.A.
登録日2015-01-27
公開日2016-02-10
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of the small terminase from thermophilic phage G20C
To Be Published
5U3W
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Human PPARdelta ligand-binding domain in complexed with specific agonist 7
分子名称: 6-(2-{[([1,1'-biphenyl]-4-carbonyl)(cyclopropyl)amino]methyl}phenoxy)hexanoic acid, DI(HYDROXYETHYL)ETHER, Peroxisome proliferator-activated receptor delta, ...
著者Wu, C.-C, Baiga, T.J, Downes, M, La Clair, J.J, Atkins, A.R, Richard, S.B, Stockley-Noel, T.A, Bowman, M.E, Evans, R.M, Noel, J.P.
登録日2016-12-03
公開日2017-03-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis for specific ligation of the peroxisome proliferator-activated receptor delta.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
1N35
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lambda3 elongation complex with four phosphodiester bond formed
分子名称: 3'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE, 5'-R(*AP*UP*UP*AP*GP*CP*CP*CP*CP*C)-3', 5'-R(P*GP*GP*GP*GP*G)-3', ...
著者Tao, Y, Farsetta, D.L, Nibert, M.L, Harrison, S.C.
登録日2002-10-25
公開日2002-12-25
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献RNA Synthesis in a Cage--Structural Studies of Reovirus Polymerase [lambda] 3
Cell(Cambridge,Mass.), 111, 2002
4WVI
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Crystal structure of the Type-I signal peptidase from Staphylococcus aureus (SpsB) in complex with a substrate peptide (pep2).
分子名称: Maltose-binding periplasmic protein,Signal peptidase IB, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, substrate peptide (pep2)
著者Young, P.G, Ting, Y.T, Baker, E.N.
登録日2014-11-05
公開日2015-09-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Peptide binding to a bacterial signal peptidase visualized by peptide tethering and carrier-driven crystallization.
IUCrJ, 3, 2016
1N34
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Structure of the Thermus thermophilus 30S ribosomal subunit in the presence of codon and crystallographically disordered near-cognate transfer rna anticodon stem-loop mismatched at the first codon position
分子名称: 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
著者Ogle, J.M, Murphy IV, F.V, Tarry, M.J, Ramakrishnan, V.
登録日2002-10-25
公開日2002-11-29
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Selection of tRNA by the Ribosome Requires a Transition from an Open to a Closed Form
Cell(Cambridge,Mass.), 111, 2002

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