5CJO
 
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6AZ2
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6AYZ
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8FIS
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6WGK
 | | Fab portion of dupilumab with Crystal Kappa design and intrachain disulfide | | 分子名称: | Dupilumab Fab heavy chain, Dupilumab Fab light chain | | 著者 | Druzina, Z, Atwell, S, Pustilnik, A, Antonysamy, S, Ho, C, Lieu, R, Hendle, J, Benach, J, Wang, J. | | 登録日 | 2020-04-05 | | 公開日 | 2020-09-16 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | | 主引用文献 | Rapid and robust antibody Fab fragment crystallization utilizing edge-to-edge beta-sheet packing.
Plos One, 15, 2020
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6WGL
 | | Dupilumab fab with Crystal Kappa design complexed with human IL-4 receptor | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Dupilumab Fab heavy chain, ... | | 著者 | Druzina, Z, Atwell, S, Pustilnik, A, Antonysamy, S, Ho, C, Lieu, R, Hendle, J, Benach, J, Wang, J. | | 登録日 | 2020-04-05 | | 公開日 | 2020-09-16 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.82 Å) | | 主引用文献 | Rapid and robust antibody Fab fragment crystallization utilizing edge-to-edge beta-sheet packing.
Plos One, 15, 2020
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6WGB
 | | Crystal structure of the fab portion of dupilumab | | 分子名称: | Dupilumab Fab heavy chain, Dupilumab Fab light chain | | 著者 | Druzina, Z, Atwell, S, Pustilnik, A, Antonysamy, S, Ho, C, Lieu, R, Hendle, J, Benach, J, Wang, J. | | 登録日 | 2020-04-05 | | 公開日 | 2020-09-16 | | 最終更新日 | 2020-09-23 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Rapid and robust antibody Fab fragment crystallization utilizing edge-to-edge beta-sheet packing.
Plos One, 15, 2020
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6WIO
 | | Fab antigen complex | | 分子名称: | Fab Heavy chain, Fab Light chain, Interleukin-17A | | 著者 | Antonysamy, S. | | 登録日 | 2020-04-10 | | 公開日 | 2020-09-23 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | | 主引用文献 | Rapid and robust antibody Fab fragment crystallization utilizing edge-to-edge beta-sheet packing.
Plos One, 15, 2020
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6WIR
 | | Fab antigen complex | | 分子名称: | Fab heavy chain, Fab light chain, Interleukin-17A | | 著者 | Antonysamy, S. | | 登録日 | 2020-04-10 | | 公開日 | 2020-09-23 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.96 Å) | | 主引用文献 | Rapid and robust antibody Fab fragment crystallization utilizing edge-to-edge beta-sheet packing.
Plos One, 15, 2020
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6WG8
 | | Fab portion of dupilumab with Crystal Kappa design | | 分子名称: | Dupilumab Fab heavy chain, Dupilumab Fab light chain, GLYCEROL | | 著者 | Druzina, Z, Atwell, S, Pustilnik, A, Antonysamy, S, Ho, C, Lieu, R, Hendle, J, Benach, J, Wang, J. | | 登録日 | 2020-04-05 | | 公開日 | 2020-09-16 | | 最終更新日 | 2020-09-23 | | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | | 主引用文献 | Rapid and robust antibody Fab fragment crystallization utilizing edge-to-edge beta-sheet packing.
Plos One, 15, 2020
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6WGJ
 | | Fab portion of dupilumab with Crystal Kappa design and no interchain disulfide | | 分子名称: | Dupilumab Fab heavy chain, Dupilumab Fab light chain | | 著者 | Druzina, Z, Atwell, S, Pustilnik, A, Antonysamy, S, Ho, C, Lieu, R, Hendle, J, Benach, J, Wang, J. | | 登録日 | 2020-04-05 | | 公開日 | 2020-09-16 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Rapid and robust antibody Fab fragment crystallization utilizing edge-to-edge beta-sheet packing.
Plos One, 15, 2020
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7R8U
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7L57
 | | Cryo-EM structure of the SARS-CoV-2 spike glycoprotein bound to Fab 2-15 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Rapp, M, Shapiro, L. | | 登録日 | 2020-12-21 | | 公開日 | 2021-04-14 | | 最終更新日 | 2021-04-21 | | 実験手法 | ELECTRON MICROSCOPY (5.87 Å) | | 主引用文献 | Modular basis for potent SARS-CoV-2 neutralization by a prevalent VH1-2-derived antibody class.
Cell Rep, 35, 2021
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7L56
 | | Cryo-EM structure of the SARS-CoV-2 spike glycoprotein bound to Fab 2-43 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 2-43 variable domain heavy chain, ... | | 著者 | Rapp, M, Shapiro, L. | | 登録日 | 2020-12-21 | | 公開日 | 2021-04-14 | | 最終更新日 | 2023-04-05 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Modular basis for potent SARS-CoV-2 neutralization by a prevalent VH1-2-derived antibody class.
Cell Rep, 35, 2021
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7L58
 | | Cryo-EM structure of the SARS-CoV-2 spike glycoprotein bound to Fab H4 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab H4 variable domain heavy chain, ... | | 著者 | Rapp, M, Shapiro, L. | | 登録日 | 2020-12-21 | | 公開日 | 2021-04-14 | | 最終更新日 | 2021-04-21 | | 実験手法 | ELECTRON MICROSCOPY (5.07 Å) | | 主引用文献 | Modular basis for potent SARS-CoV-2 neutralization by a prevalent VH1-2-derived antibody class.
Cell Rep, 35, 2021
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3U7Y
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4HHA
 | | Anti-Human Cytomegalovirus (HCMV) Fab KE5 with epitope peptide AD-2S1 | | 分子名称: | Antibody KE5, CHLORIDE ION, Fab KE5, ... | | 著者 | Bryson, S, Risnes, L, Damgupta, S, Thomson, C.A, Pfoh, R, Schrader, J.W, Pai, E.F. | | 登録日 | 2012-10-09 | | 公開日 | 2013-10-23 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structures of Preferred Human IgV Genes-Based Protective Antibodies Identify How Conserved Residues Contact Diverse Antigens and Assign Source of Specificity to CDR3 Loop Variation.
J. Immunol., 196, 2016
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4HIE
 | | Anti-Streptococcus pneumoniae 23F Fab 023.102 | | 分子名称: | Antibody 023.102, Fab 023.102 | | 著者 | Bryson, S, Risnes, L, Damgupta, S, Thomson, C.A, Schrader, J.W, Pai, E.F. | | 登録日 | 2012-10-11 | | 公開日 | 2013-08-28 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structures of Preferred Human IgV Genes-Based Protective Antibodies Identify How Conserved Residues Contact Diverse Antigens and Assign Source of Specificity to CDR3 Loop Variation.
J. Immunol., 196, 2016
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4HIH
 | | Anti-Streptococcus pneumoniae 23F Fab 023.102 with bound rhamnose. | | 分子名称: | Antibody 023.102, Fab 023.102, alpha-L-rhamnopyranose | | 著者 | Bryson, S, Risnes, L, Damgupta, S, Thomson, C.A, Schrader, J.W, Pai, E.F. | | 登録日 | 2012-10-11 | | 公開日 | 2013-08-28 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structures of Preferred Human IgV Genes-Based Protective Antibodies Identify How Conserved Residues Contact Diverse Antigens and Assign Source of Specificity to CDR3 Loop Variation.
J. Immunol., 196, 2016
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7V05
 | | Complex of Plasmodium falciparum circumsporozoite protein with 850 Fab | | 分子名称: | 850 Fab Heavy Chain, 850 Fab Light Chain, Circumsporozoite protein | | 著者 | Kucharska, I, Prieto, K, Rubinstein, J.L, Julien, J.P. | | 登録日 | 2022-05-09 | | 公開日 | 2022-11-23 | | 最終更新日 | 2022-12-14 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | High-density binding to Plasmodium falciparum circumsporozoite protein repeats by inhibitory antibody elicited in mouse with human immunoglobulin repertoire.
Plos Pathog., 18, 2022
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7UYM
 | | 850 Fab in complex with NANPNANPNANP peptide | | 分子名称: | 850 Fab Heavy Chain, 850 Fab Light Chain, Circumsporozoite protein, ... | | 著者 | Kucharska, I, Prieto, K, Julien, J.P. | | 登録日 | 2022-05-06 | | 公開日 | 2022-11-23 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | High-density binding to Plasmodium falciparum circumsporozoite protein repeats by inhibitory antibody elicited in mouse with human immunoglobulin repertoire.
Plos Pathog., 18, 2022
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7UYL
 | | 850 Fab | | 分子名称: | 850 Fab Heavy Chain, 850 Fab Light Chain, GLYCEROL, ... | | 著者 | Kucharska, I, Prieto, K, Julien, J.P. | | 登録日 | 2022-05-06 | | 公開日 | 2022-11-23 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | High-density binding to Plasmodium falciparum circumsporozoite protein repeats by inhibitory antibody elicited in mouse with human immunoglobulin repertoire.
Plos Pathog., 18, 2022
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6TKB
 | | ChiLob 7/4 H2 HC-C224S F(ab')2 | | 分子名称: | Chilob 7/4 H2 heavy chain C224S, Chilob 7/4 H2 kappa chain | | 著者 | Orr, C.M, Fisher, H, Tews, I. | | 登録日 | 2019-11-28 | | 公開日 | 2021-06-09 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Hinge disulfides in human IgG2 CD40 antibodies modulate receptor signaling by regulation of conformation and flexibility.
Sci Immunol, 7, 2022
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6TKF
 | | ChiLob 7/4 H2 HC-C225S KappaLC-C214S F(ab')2 | | 分子名称: | ChiLob 7/4 H2 Heavy chain C225S, ChiLob 7/4 H2 Kappa light chain C214S | | 著者 | Orr, C.M, Fisher, H, Tews, I. | | 登録日 | 2019-11-28 | | 公開日 | 2021-06-09 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | | 主引用文献 | Hinge disulfides in human IgG2 CD40 antibodies modulate receptor signaling by regulation of conformation and flexibility.
Sci Immunol, 7, 2022
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7T84
 | | Structure of angiotensin II type I receptor (AT1R) nanobody antagonist AT118i4h32 G26D T57I variant | | 分子名称: | CITRIC ACID, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | 著者 | Nemeth, G.R, Skiba, M.A, Kruse, A.C. | | 登録日 | 2021-12-15 | | 公開日 | 2022-12-07 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | An in silico method to assess antibody fragment polyreactivity.
Nat Commun, 13, 2022
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