7R8U

LOX-1 - Structural and Functional Studies of a Receptor Implicated in Atherosclerosis

This is a non-PDB format compatible entry.

Summary for 7R8U

• Entry DOI: 10.2210/pdb7r8u/pdb
• Descriptor: Oxidized low-density lipoprotein receptor 1, Antigen binding fragment, Vh and Ch1, Antibody light chain, kappa, ... (5 entities in total)
• Functional Keywords: low density lipoprotein receptor antibody complex lox-1 scavenger receptor atherogenesis-atherosclerosis macrophage cardiovascular disease, signaling protein-immune system complex, signaling protein/immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 77981.45

Authors

Oganesyan, V.,van Dyk, N. (deposition date: 2021-06-27, release date: 2022-06-01, Last modification date: 2024-10-23)

• Primary citation: Ongstad, E.L.,Gaddipati, R.,Belkhodja, M.,van Dyk, N.,Levy, S.,Sagar, D.,Cariuk, P.,Wolny, M.,Hanna, R.N.,Borrok, M.J.,Buchanan, A.,Oganesyan, V.,Gupta, R.; Structural and functional studies of a monoclonal antibody blocking LOX-1; Commun Med, 2023

Experimental method

X-RAY DIFFRACTION (1.901 Å)