7V05

Complex of Plasmodium falciparum circumsporozoite protein with 850 Fab

Summary for 7V05

• Entry DOI: 10.2210/pdb7v05/pdb
• Related: 7UYL 7UYM
• EMDB information: 26936
• Descriptor: 850 Fab Heavy Chain, 850 Fab Light Chain, Circumsporozoite protein (3 entities in total)
• Functional Keywords: antibody, malaria, plasmodium falciparum, circumsporozoite protein, antimicrobial protein, immune system-cell invasion complex, immune system/cell invasion
• Biological source: Mus musculus; More
• Total number of polymer chains: 29
• Total formula weight: 707927.16

Authors

Kucharska, I.,Prieto, K.,Rubinstein, J.L.,Julien, J.P. (deposition date: 2022-05-09, release date: 2022-11-23, Last modification date: 2022-12-14)

• Primary citation: Kucharska, I.,Binter, S.,Murugan, R.,Scally, S.W.,Ludwig, J.,Prieto, K.,Thai, E.,Costa, G.,Li, K.,Horn, G.Q.,Flores-Garcia, Y.,Bosch, A.,Sicard, T.,Rubinstein, J.L.,Zavala, F.,Dennison, S.M.,Tomaras, G.D.,Levashina, E.A.,Kellam, P.,Wardemann, H.,Julien, J.P.; High-density binding to Plasmodium falciparum circumsporozoite protein repeats by inhibitory antibody elicited in mouse with human immunoglobulin repertoire.; Plos Pathog., 18:e1010999-e1010999, 2022; PubMed: 36441829; DOI: 10.1371/journal.ppat.1010999

Experimental method

ELECTRON MICROSCOPY (3.4 Å)