7UYM

850 Fab in complex with NANPNANPNANP peptide

Summary for 7UYM

Entry DOI	10.2210/pdb7uym/pdb
Related	7UYL 7V05
Descriptor	850 Fab Heavy Chain, VHH nanobody, 850 Fab Light Chain, ... (5 entities in total)
Functional Keywords	antibody, malaria, plasmodium falciparum, circumsporozoite protein, antimicrobial protein, immune system
Biological source	Mus musculus More
Total number of polymer chains	4
Total formula weight	60243.54
Authors	Kucharska, I.,Prieto, K.,Julien, J.P. (deposition date: 2022-05-06, release date: 2022-11-23, Last modification date: 2023-10-25)
Primary citation	Kucharska, I.,Binter, S.,Murugan, R.,Scally, S.W.,Ludwig, J.,Prieto, K.,Thai, E.,Costa, G.,Li, K.,Horn, G.Q.,Flores-Garcia, Y.,Bosch, A.,Sicard, T.,Rubinstein, J.L.,Zavala, F.,Dennison, S.M.,Tomaras, G.D.,Levashina, E.A.,Kellam, P.,Wardemann, H.,Julien, J.P. High-density binding to Plasmodium falciparum circumsporozoite protein repeats by inhibitory antibody elicited in mouse with human immunoglobulin repertoire. Plos Pathog., 18:e1010999-e1010999, 2022 Cited by PubMed: 36441829 DOI: 10.1371/journal.ppat.1010999 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation