PDB: 224004 件ウェブページステータス検索Chemie searchBIRD

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3DGO	A non-biological ATP binding protein with a Tyr-Phe mutation in the ligand binding domain 分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATP Binding Protein-DX, CHLORIDE ION, ... 著者 Simmons, C.R, Allen, J.P, Chaput, J.C. 登録日 2008-06-13 公開日 2009-06-30 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 A synthetic protein selected for ligand binding affinity mediates ATP hydrolysis. Acs Chem.Biol., 4, 2009
3EFX	Novel binding site identified in a hybrid between cholera toxin and heat-labile enterotoxin, 1.9A crystal structure reveals the details 分子名称: Cholera enterotoxin subunit B, Heat-labile enterotoxin B chain, alpha-L-fucopyranose-(1-2)-[2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-3)]beta-D-galactopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]beta-D-glucopyranose 著者 Holmner, A, Lebens, M, Teneberg, S, Angstrom, J, Okvist, M, Krengel, U. 登録日 2008-09-10 公開日 2008-09-23 最終更新日 2024-04-10 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Novel binding site identified in a hybrid between cholera toxin and heat-labile enterotoxin: 1.9 A crystal structure reveals the details Structure, 12, 2004
3F8G	The X-ray structure of a dimeric variant of human pancreatic ribonuclease with high cytotoxic and antitumor activities 分子名称: Ribonuclease pancreatic, SULFATE ION 著者 Merlino, A, Avella, G, Mazzarella, L, Sica, F. 登録日 2008-11-12 公開日 2009-02-10 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural features for the mechanism of antitumor action of a dimeric human pancreatic ribonuclease variant. Protein Sci., 18, 2009
3IA3	A cis-proline in alpha-hemoglobin stabilizing Protein directs the structural reorganization of alpha-hemoglobin 分子名称: Alpha-hemoglobin-stabilizing protein, Hemoglobin subunit alpha, PROTOPORPHYRIN IX CONTAINING FE 著者 Feng, L, Jeffrey, P.D, Shi, Y. 登録日 2009-07-13 公開日 2009-07-28 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 A cis-proline in alpha-hemoglobin stabilizing protein directs the structural reorganization of alpha-hemoglobin. J.Biol.Chem., 284, 2009
2UXZ	Two-Carbon-Elongated HIV-1 Protease Inhibitors with a Tertiary- Alcohol-Containing Transition-State Mimic 分子名称: HIV-1 PROTEASE, METHYL [(1S)-1-({2-[(4R)-4-BENZYL-4-HYDROXY-5-{[(1S,2R)-2-HYDROXY-2,3-DIHYDRO-1H-INDEN-1-YL]AMINO}-5-OXOPENTYL]-2-(4-BROMOBENZYL)HYDRAZINO}CARBONYL)-2,2-DIMETHYLPROPYL]CARBAMATE 著者 Ginman, N, Samuelsson, B, Hallberg, A, Unge, J.T, Unge, T.K. 登録日 2007-04-02 公開日 2008-05-20 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Two-Carbon-Elongated HIV-1 Protease Inhibitors with a Tertiary-Alcohol-Containing Transition-State Mimic. J.Med.Chem., 51, 2008
2UY0	Two-Carbon-Elongated HIV-1 Protease Inhibitors with a Tertiary- Alcohol-Containing Transition-State Mimic 分子名称: HIV-1 PROTEASE, METHYL [(1S)-1-({2-[(4R)-4-BENZYL-4-HYDROXY-5-{[(1S,2R)-2-HYDROXY-2,3-DIHYDRO-1H-INDEN-1-YL]AMINO}-5-OXOPENTANOYL]-2-(4-BROMOBENZYL)HYDRAZINO}CARBONYL)-2,2-DIMETHYLPROPYL]CARBAMATE 著者 Ginman, N, Samuelsson, B, Hallberg, A, Unge, J.T, Unge, T.K. 登録日 2007-04-02 公開日 2008-05-20 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Two-Carbon-Elongated HIV-1 Protease Inhibitors with a Tertiary-Alcohol-Containing Transition-State Mimic. J.Med.Chem., 51, 2008
2W1U	A family 32 carbohydrate-binding module, from the Mu toxin produced by Clostridium perfringens, in complex with beta-D-glcNAc-beta(1,3) galNAc 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-alpha-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose, ACETATE ION, ... 著者 Ficko-Blean, E, Boraston, A.B. 登録日 2008-10-20 公開日 2009-05-05 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 N-Acetylglucosamine Recognition by a Family 32 Carbohydrate-Binding Module from Clostridium Perfringens Nagh. J.Mol.Biol., 390, 2009
2VY9	Molecular architecture of the stressosome, a signal integration and transduction hub 分子名称: ANTI-SIGMA-FACTOR ANTAGONIST 著者 Marles-Wright, J, Grant, T, Delumeau, O, van Duinen, G, Firbank, S.J, Lewis, P.J, Murray, J.W, Newman, J.A, Quin, M.B, Race, P.R, Rohou, A, Tichelaar, W, van Heel, M, Lewis, R.J. 登録日 2008-07-21 公開日 2008-10-14 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Molecular Architecture of the "Stressosome," a Signal Integration and Transduction Hub Science, 322, 2008
7WX6	A Legionella acetyltransferase VipF 分子名称: CHLORAMPHENICOL, COENZYME A, N-acetyltransferase 著者 Chen, T.T, Lin, Y.L, Chen, Z, Han, A.D. 登録日 2022-02-14 公開日 2022-09-14 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.273 Å) 主引用文献 Structural basis for the acetylation mechanism of the Legionella effector VipF. Acta Crystallogr D Struct Biol, 78, 2022
2WDB	A family 32 carbohydrate-binding module, from the Mu toxin produced by Clostridium perfringens, in complex with beta-D-glcNAc-beta(1,2) mannose 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose, CALCIUM ION, HYALURONOGLUCOSAMINIDASE 著者 Ficko-Blean, E, Boraston, A.B. 登録日 2009-03-23 公開日 2009-05-05 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 N-Acetylglucosamine Recognition by a Family 32 Carbohydrate-Binding Module from Clostridium Perfringens Nagh. J.Mol.Biol., 390, 2009
4AO8	PEG-bound complex of a novel cold-adapted esterase from an Arctic intertidal metagenomic library 分子名称: DI(HYDROXYETHYL)ETHER, ESTERASE 著者 Fu, J, Leiros, H.-K.S, Pascale, D.d, Johnson, K.A, Blencke, H.M, Landfald, B. 登録日 2012-03-23 公開日 2012-08-08 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.61 Å) 主引用文献 Functional and Structural Studies of a Novel Cold-Adapted Esterase from an Arctic Intertidal Metagenomic Library. Appl.Microbiol.Biotechnol., 97, 2013
1Q0P	A domain of Factor B 分子名称: Complement factor B, MANGANESE (II) ION 著者 Bhattacharya, A.A, Liddington, R.C. 登録日 2003-07-17 公開日 2004-03-30 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal Structure of the A Domain from Complement Factor B Reveals an Integrin-like Open Conformation. STRUCTURE, 12, 2004
2V5I	Structure of the receptor-binding protein of bacteriophage Det7: a podoviral tailspike in a myovirus 分子名称: SALMONELLA TYPHIMURIUM DB7155 BACTERIOPHAGE DET7 TAILSPIKE, SODIUM ION 著者 Walter, M, Fiedler, C, Grassl, R, Biebl, M, Rachel, R, Hermo-Parrado, X.L, Llamas-Saiz, A.L, Seckler, R, Miller, S, van Raaij, M.J. 登録日 2007-07-05 公開日 2008-02-19 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structure of the Receptor-Binding Protein of Bacteriophage Det7: A Podoviral Tail Spike in a Myovirus. J.Virol., 82, 2008
4RUZ	Crystal structure of human Carbonic Anhydrase II in complex with 4-ethoxybenzenesulfonamide 分子名称: 4-ethoxybenzenesulfonamide, Carbonic anhydrase 2, GLYCEROL, ... 著者 Pinard, M.A, Mckenna, R. 登録日 2014-11-23 公開日 2015-04-22 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 A class of sulfonamide carbonic anhydrase inhibitors with neuropathic pain modulating effects. Bioorg.Med.Chem., 23, 2015
6HRP	CRYSTAL STRUCTURE OF BTK KINASE DOMAIN COMPLEXED WITH 6-(dimethylamino)-2-[2-(hydroxymethyl)-3-[1-methyl-5-[[5-(morpholine-4-carbonyl)-2-pyridyl]amino]-6-oxo-3-pyridyl]phenyl]-3,4-dihydroisoquinolin-1-one 分子名称: 6-~{tert}-butyl-8-fluoranyl-2-[2-(hydroxymethyl)-3-[1-methyl-5-[(5-morpholin-4-ylcarbonylpyridin-2-yl)amino]-6-oxidanylidene-pyridazin-3-yl]phenyl]phthalazin-1-one, Tyrosine-protein kinase BTK 著者 Janson, C, Kuglstatter, A. 登録日 2018-09-28 公開日 2019-03-20 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.12 Å) 主引用文献 A potent seven-membered cyclic BTK (Bruton's tyrosine Kinase) chiral inhibitor conceived by structure-based drug design to lock its bioactive conformation. Bioorg.Med.Chem.Lett., 29, 2019
7WX5	a Legionella acetyltransferase effector VipF 分子名称: ACETYL COENZYME *A, N-acetyltransferase 著者 Chen, T.T, Lin, Y.L, Zhang, S.J, Han, A.D. 登録日 2022-02-14 公開日 2023-02-22 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.392 Å) 主引用文献 Structural basis for the acetylation mechanism of the Legionella effector VipF. Acta Crystallogr D Struct Biol, 78, 2022
4GX8	Crystal structure of a DNA polymerase III alpha-epsilon chimera 分子名称: CHLORIDE ION, DNA polymerase III subunit epsilon,DNA polymerase III subunit alpha 著者 Robinson, A, Horan, N, Xu, Z.-Q, Dixon, N.E, Oakley, A.J. 登録日 2012-09-04 公開日 2013-04-03 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Proofreading exonuclease on a tether: the complex between the E. coli DNA polymerase III subunits alpha, {varepsilon}, theta and beta reveals a highly flexible arrangement of the proofreading domain Nucleic Acids Res., 41, 2013
4AO6	Native structure of a novel cold-adapted esterase from an Arctic intertidal metagenomic library 分子名称: ESTERASE 著者 Fu, J, Leiros, H.-K.S, Pascale, D.d, Johnson, K.A, Blencke, H.M, Landfald, B. 登録日 2012-03-23 公開日 2012-08-08 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Functional and Structural Studies of a Novel Cold-Adapted Esterase from an Arctic Intertidal Metagenomic Library. Appl.Microbiol.Biotechnol., 97, 2013
7MEU	A biphenyl inhibitor of eIF4E targeting an internal binding site enables the design of cell-permeable PROTAC-degraders 分子名称: (2E)-2-{2-[4-([1,1'-biphenyl]-4-yl)-1,3-thiazol-2-yl]hydrazinylidene}-3-(2-nitrophenyl)propanoic acid, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, Eukaryotic translation initiation factor 4E 著者 Papadopoulos, E. 登録日 2021-04-07 公開日 2021-04-28 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 A biphenyl inhibitor of eIF4E targeting an internal binding site enables the design of cell-permeable PROTAC-degraders. Eur.J.Med.Chem., 219, 2021
4KC9	Structure of HHARI, a RING-IBR-RING ubiquitin ligase: autoinhibition of an Ariadne-family E3 and insights into ligation mechanism 分子名称: E3 ubiquitin-protein ligase ARIH1, ZINC ION 著者 Duda, D.M, Olszewski, J.L, Schulman, B.A. 登録日 2013-04-24 公開日 2013-05-29 最終更新日 2013-07-03 実験手法 X-RAY DIFFRACTION (3.603 Å) 主引用文献 Structure of HHARI, a RING-IBR-RING Ubiquitin Ligase: Autoinhibition of an Ariadne-Family E3 and Insights into Ligation Mechanism. Structure, 21, 2013
4BNA	REVERSIBLE BENDING AND HELIX GEOMETRY IN A B-DNA DODECAMER: CGCGAATTBRCGCG 分子名称: DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*(CBR)P*GP*CP*G)-3') 著者 Kopka, M.L, Fratini, A.V, Dickerson, R.E. 登録日 1982-02-16 公開日 1982-04-15 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Reversible bending and helix geometry in a B-DNA dodecamer: CGCGAATTBrCGCG. J.Biol.Chem., 257, 1982
212D	INFLUENCE OF COUNTER-IONS ON THE CRYSTAL STRUCTURES OF DNA DECAMERS: BINDING OF [CO(NH3)6]3+ AND BA2+ TO A-DNA 分子名称: COBALT HEXAMMINE(III), DNA (5'-D(*AP*CP*CP*GP*GP*CP*CP*GP*GP*T)-3') 著者 Gao, Y.-G, Robinson, H, Van Boom, J.H, Wang, A.H.-J. 登録日 1995-06-26 公開日 1996-01-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Influence of counter-ions on the crystal structures of DNA decamers: binding of [Co(NH3)6]3+ and Ba2+ to A-DNA. Biophys.J., 69, 1995
1PUT	AN NMR-DERIVED MODEL FOR THE SOLUTION STRUCTURE OF OXIDIZED PUTIDAREDOXIN, A 2FE, 2-S FERREDOXIN FROM PSEUDOMONAS 分子名称: FE2/S2 (INORGANIC) CLUSTER, PUTIDAREDOXIN 著者 Pochapsky, T.C, Ye, X.M, Ratnaswamy, G, Lyons, T.A. 登録日 1994-07-09 公開日 1994-09-30 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 An NMR-derived model for the solution structure of oxidized putidaredoxin, a 2-Fe, 2-S ferredoxin from Pseudomonas. Biochemistry, 33, 1994
4RUX	Crystal structure of human Carbonic Anhydrase II in complex with 4-(allyloxy)benzenesulfonamide 分子名称: 4-(allyloxy)benzenesulfonamide, Carbonic anhydrase 2, GLYCEROL, ... 著者 Pinard, M.A, Mckenna, R. 登録日 2014-11-23 公開日 2015-04-22 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.14 Å) 主引用文献 A class of sulfonamide carbonic anhydrase inhibitors with neuropathic pain modulating effects. Bioorg.Med.Chem., 23, 2015
3GHD	Crystal structure of a cystathionine beta-synthase domain protein fused to a Zn-ribbon-like domain 分子名称: a cystathionine beta-synthase domain protein fused to a Zn-ribbon-like domain 著者 Dong, A, Xu, X, Chruszcz, M, Brown, G, Proudfoot, M, Edwards, A.M, Joachimiak, A, Minor, W, Savchenko, A, Yaleunin, A, Midwest Center for Structural Genomics (MCSG) 登録日 2009-03-03 公開日 2009-03-31 最終更新日 2022-04-13 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 Crystal structure of a cystathionine beta-synthase domain protein fused to a Zn-ribbon-like domain To be Published

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