3EFX

Novel binding site identified in a hybrid between cholera toxin and heat-labile enterotoxin, 1.9A crystal structure reveals the details

Replaces:  2NZGReplaces:  1TL0

Summary for 3EFX

• Entry DOI: 10.2210/pdb3efx/pdb
• Descriptor: Cholera enterotoxin subunit B, Heat-labile enterotoxin B chain, alpha-L-fucopyranose-(1-2)-[2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-3)]beta-D-galactopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]beta-D-glucopyranose (3 entities in total)
• Functional Keywords: protein-carbohydrate complex, cholera toxin, heat-labile enterotoxin, blood group antigen, toxin
• Biological source: Vibrio cholerae
• Total number of polymer chains: 10
• Total formula weight: 124440.05

Authors

Holmner, A.,Lebens, M.,Teneberg, S.,Angstrom, J.,Okvist, M.,Krengel, U. (deposition date: 2008-09-10, release date: 2008-09-23, Last modification date: 2024-04-10)

• Primary citation: Holmner, A.,Lebens, M.,Teneberg, S.,Angstrom, J.,Okvist, M.,Krengel, U.; Novel binding site identified in a hybrid between cholera toxin and heat-labile enterotoxin: 1.9 A crystal structure reveals the details; Structure, 12:1655-1667, 2004; PubMed: 15341730; DOI: 10.1016/j.str.2004.06.022

Experimental method

X-RAY DIFFRACTION (1.94 Å)