PDB: 42250 件ウェブページステータス検索Chemie searchBIRD

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4R5B	Human Carbonic Anhydrase II in Complex with a Carbohydrate-Based Sulfamate 分子名称: (6S)-2,6-anhydro-6-{[(3R)-3-(sulfamoyloxy)pyrrolidin-1-yl]sulfonyl}-D-glucitol, Carbonic anhydrase 2, GLYCEROL, ... 著者 Mahon, B.P, McKenna, R. 登録日 2014-08-20 公開日 2014-10-15 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural Insights into Carbonic Anhydrase IX Isoform Specificity of Carbohydrate-Based Sulfamates. J.Med.Chem., 57, 2014
6V6W	Crystal structure of antibody 438-B11 DSS mutant (Cys98A-100aA) in complex with an uncleaved prefusion optimized (UFO) soluble BG505 trimer and Fab 35O22 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 Fab Heavy chain, ... 著者 Kumar, S, Wilson, I.A. 登録日 2019-12-06 公開日 2020-09-23 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (6.5 Å) 主引用文献 A VH1-69 antibody lineage from an infected Chinese donor potently neutralizes HIV-1 by targeting the V3 glycan supersite Sci Adv, 6, 2020
6W1T	RT XFEL structure of Photosystem II 250 microseconds after the second illumination at 2.01 Angstrom resolution 分子名称: 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ... 著者 Ibrahim, M, Fransson, T, Chatterjee, R, Cheah, M.H, Hussein, R, Lassalle, L, Sutherlin, K.D, Young, I.D, Fuller, F.D, Gul, S, Kim, I.-S, Simon, P.S, de Lichtenberg, C, Chernev, P, Bogacz, I, Pham, C, Orville, A.M, Saichek, N, Northen, T.R, Batyuk, A, Carbajo, S, Alonso-Mori, R, Tono, K, Owada, S, Bhowmick, A, Bolotovski, R, Mendez, D, Moriarty, N.W, Holton, J.M, Dobbek, H, Brewster, A.S, Adams, P.D, Sauter, N.K, Bergmann, U, Zouni, A, Messinger, J, Kern, J, Yachandra, V.K, Yano, J. 登録日 2020-03-04 公開日 2020-05-13 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Untangling the sequence of events during the S2→ S3transition in photosystem II and implications for the water oxidation mechanism. Proc.Natl.Acad.Sci.USA, 117, 2020
7K2W	Crystal structure of CTX-M-14 E166A/K234R Beta-lactamase in complex with hydrolyzed cefotaxime 分子名称: Beta-lactamase, CEFOTAXIME, C3' cleaved, ... 著者 Lu, S, Palzkill, T, Sankaran, B, Hu, L, Soeung, V, Prasad, B.V.V. 登録日 2020-09-09 公開日 2020-11-04 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 A drug-resistant beta-lactamase variant changes the conformation of its active-site proton shuttle to alter substrate specificity and inhibitor potency. J.Biol.Chem., 295, 2020
4QRH	Molecular mechanism and evolution of guanylate kinase regulation by (p)ppGpp 分子名称: 1,2-ETHANEDIOL, Guanylate kinase, MAGNESIUM ION, ... 著者 Liu, K, Krasny, K, Myers, A.R, Satyshur, K.A, Keck, J.L, Wnag, J.D. 登録日 2014-07-01 公開日 2015-02-25 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Molecular Mechanism and Evolution of Guanylate Kinase Regulation by (p)ppGpp. Mol.Cell, 57, 2015
7JH3	Crystal structure of 4-aminobutyrate aminotransferase PuuE from Escherichia coli in complex with PLP 分子名称: 4-aminobutyrate aminotransferase PuuE, DI(HYDROXYETHYL)ETHER 著者 Valleau, D, Evdokimova, E, Stogios, P.J, Di Leo, R, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2020-07-20 公開日 2020-08-12 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.68 Å) 主引用文献 Crystal structure of 4-aminobutyrate aminotransferase PuuE from Escherichia coli in complex with PLP To Be Published
7QRU	Structure of Bacillus pseudofirmus Mrp antiporter complex, monomer 分子名称: 1,2-Distearoyl-sn-glycerophosphoethanolamine, Na(+)/H(+) antiporter subunit B, Na(+)/H(+) antiporter subunit C, ... 著者 Lee, Y. 登録日 2022-01-12 公開日 2022-11-09 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (2.24 Å) 主引用文献 Ion transfer mechanisms in Mrp-type antiporters from high resolution cryoEM and molecular dynamics simulations. Nat Commun, 13, 2022
7JJ8	Crystal structure of the Zn(II)-bound ZnuA-like domain of Streptococcus pneumoniae AdcA 分子名称: ZINC ION, Zinc-binding lipoprotein AdcA 著者 Luo, Z, More, J.R, Kobe, B, McDevitt, C.A. 登録日 2020-07-24 公開日 2020-12-23 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 A Trap-Door Mechanism for Zinc Acquisition by Streptococcus pneumoniae AdcA. Mbio, 12, 2021
7JSY	Proteinase K soaked with I3C determined by MicroED from a single milled microcrystal 分子名称: 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid, Proteinase K 著者 Martynowycz, M.W, Gonen, T. 登録日 2020-08-16 公開日 2020-10-14 最終更新日 2024-11-13 実験手法 ELECTRON CRYSTALLOGRAPHY (1.78 Å) 主引用文献 Ligand Incorporation into Protein Microcrystals for MicroED by On-Grid Soaking. Structure, 29, 2021
8U2Q	Crystal Structure of Glycine--tRNA ligase active site chimera from Mycobacterium thermoresistibile/tuberculosis (G5A bound) 分子名称: 1,2-ETHANEDIOL, 5'-O-(glycylsulfamoyl)adenosine, CHLORIDE ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2023-09-06 公開日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Crystal Structure of Glycine--tRNA ligase active site chimera from Mycobacterium thermoresistibile/tuberculosis (G5A bound) To be published
6E4V	The Crystal Structure of FhuE from E. coli in complex with its substrate Coprogen 分子名称: COPROGEN, FhuE receptor, octyl beta-D-glucopyranoside 著者 Grinter, R, Lithgow, T. 登録日 2018-07-18 公開日 2019-04-10 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Determination of the molecular basis for coprogen import by Gram-negative bacteria. Iucrj, 6, 2019
7JME	Structure of the SARS-CoV-2 NSP3 Macro X domain in complex with cyclic AMP 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Non-structural protein 3 著者 Vuksanovic, N, Melkonian, T.R, Silvaggi, N.R. 登録日 2020-07-31 公開日 2020-09-02 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Discovery of Drug-Like Ligands for the Mac1 Domain of SARS-CoV-2 Nsp3. Slas Discov, 25, 2020
7JTL	Structure of SARS-CoV-2 ORF8 accessory protein 分子名称: ORF8 protein, SODIUM ION 著者 Flower, T.G, Buffalo, C.Z, Hooy, R.M, Allaire, M, Ren, X, Hurley, J.H. 登録日 2020-08-18 公開日 2020-08-26 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Structure of SARS-CoV-2 ORF8, a rapidly evolving immune evasion protein. Proc.Natl.Acad.Sci.USA, 118, 2021
4QUO	Crystal structure of Aminopeptidase N in complex with the phosphinic dipeptide analogue LL-(R,S)-hPheP[CH2]Phe(3-CH2NH2) 分子名称: (2S)-2-[3-(aminomethyl)benzyl]-3-[(R)-[(1R)-1-amino-3-phenylpropyl](hydroxy)phosphoryl]propanoic acid, Aminopeptidase N, GLYCEROL, ... 著者 Nocek, B, Mulligan, R, Joachimiak, A, Vassiliou, S, Berlicki, L, Mucha, A. 登録日 2014-07-11 公開日 2014-09-10 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structure-guided, single-point modifications in the phosphinic dipeptide structure yield highly potent and selective inhibitors of neutral aminopeptidases. J.Med.Chem., 57, 2014
4QVF	Crystal structure of Bcl-xL in complex with BIM BH3 domain 分子名称: Bcl-2-like protein 1, Peptide from Bcl-2-like protein 11 著者 Sreekanth, R, Yoon, H.S. 登録日 2014-07-15 公開日 2015-06-10 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.531 Å) 主引用文献 Bh3 induced conformational changes in Bcl-Xl revealed by crystal structure and comparative analysis. Proteins, 83, 2015
4RB0	Crystal structure of Magnetospirillum gryphiswaldense MSR-1 SeMet-Apo-Fur 分子名称: CITRATE ANION, DNA-binding transcriptional dual regulator of siderophore biosynthesis and transport(Fur family), SULFATE ION 著者 Deng, Z, Chen, Z. 登録日 2014-09-12 公開日 2015-07-15 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Mechanistic insights into metal ion activation and operator recognition by the ferric uptake regulator. Nat Commun, 6
7QTA	S1 nuclease from Aspergillus oryzae in complex with uridine 分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Nuclease S1, ... 著者 Adamkova, K, Koval, T, Kolenko, P, Oestergaard, L.H, Dohnalek, J. 登録日 2022-01-14 公開日 2022-11-09 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.06 Å) 主引用文献 Atomic resolution studies of S1 nuclease complexes reveal details of RNA interaction with the enzyme despite multiple lattice-translocation defects. Acta Crystallogr D Struct Biol, 78, 2022
6CC9	NMR data-driven model of GTPase KRas-GMPPNP:Cmpd2 complex tethered to a nanodisc 分子名称: (2R,4S)-4-[(5-bromo-1H-indole-3-carbonyl)amino]-2-[(4-chlorophenyl)methyl]piperidin-1-ium, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Apolipoprotein A-I, ... 著者 Fang, Z, Marshall, C.B, Nishikawa, T, Gossert, A.D, Jansen, J.M, Jahnke, W, Ikura, M. 登録日 2018-02-06 公開日 2018-09-05 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Inhibition of K-RAS4B by a Unique Mechanism of Action: Stabilizing Membrane-Dependent Occlusion of the Effector-Binding Site. Cell Chem Biol, 25, 2018
7JVU	Crystal structure of human histone deacetylase 8 (HDAC8) I45T mutation complexed with SAHA 分子名称: 1,2-ETHANEDIOL, Histone deacetylase 8, OCTANEDIOIC ACID HYDROXYAMIDE PHENYLAMIDE, ... 著者 Osko, J.D, Christianson, D.W, Decroos, C, Porter, N.J, Lee, M. 登録日 2020-08-24 公開日 2020-12-16 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.5004766 Å) 主引用文献 Structural analysis of histone deacetylase 8 mutants associated with Cornelia de Lange Syndrome spectrum disorders. J.Struct.Biol., 213, 2020
6VZR	Engineered TTLL6 bound to the initiation analog 分子名称: (2~{S})-2-[[[(3~{R})-3-acetamido-4-(ethylamino)-4-oxidanylidene-butyl]-phosphonooxy-phosphoryl]methyl]pentanedioic acid, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ... 著者 Mahalingan, K.K, Keenen, E.K, Strickland, M, Li, Y, Liu, Y, Ball, H.L, Tanner, M.E, Tjandra, N, Roll-Mecak, A. 登録日 2020-02-28 公開日 2020-08-12 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural basis for polyglutamate chain initiation and elongation by TTLL family enzymes. Nat.Struct.Mol.Biol., 27, 2020
6CBC	Crystal structure of an N-terminal fragment of Vps13. 分子名称: Vacuolar protein sorting-associated protein 著者 Kumar, N, Horenkamp, F.A, Reinisch, K.M. 登録日 2018-02-02 公開日 2018-08-08 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 VPS13A and VPS13C are lipid transport proteins differentially localized at ER contact sites. J. Cell Biol., 217, 2018
6WAC	FF248-249AA PCNA mutant defective in BIR 分子名称: Proliferating cell nuclear antigen 著者 Ripley, B.M, Washington, M.T. 登録日 2020-03-25 公開日 2020-09-30 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural analysis of PCNA mutant proteins defective in BIR, FF248-249AA and R80A To be Published
8U2P	Crystal Structure of Glycine--tRNA ligase from Mycobacterium tuberculosis (G5A bound) 分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5'-O-(glycylsulfamoyl)adenosine, ... 著者 Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2023-09-06 公開日 2023-09-13 最終更新日 2024-04-10 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Crystal Structure of Glycine--tRNA ligase from Mycobacterium tuberculosis (G5A bound) To be published
6VZZ	Crystal structure of glucokinase from Balamuthia mandrillaris in complex with glucose 分子名称: 1,2-ETHANEDIOL, BamaA.19900.a, CALCIUM ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2020-02-28 公開日 2020-03-25 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Characterization of Glucokinases from Pathogenic Free-Living Amoebae. Antimicrob.Agents Chemother., 2022
7JL3	Cryo-EM structure of RIG-I:dsRNA filament in complex with RIPLET PrySpry domain (trimer) 分子名称: ADENOSINE-5'-DIPHOSPHATE, Antiviral innate immune response receptor RIG-I, E3 ubiquitin-protein ligase RNF135, ... 著者 Kato, K, Ahmad, S, Hur, S. 登録日 2020-07-29 公開日 2020-12-09 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Structural analysis of RIG-I-like receptors reveals ancient rules of engagement between diverse RNA helicases and TRIM ubiquitin ligases. Mol.Cell, 81, 2021

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