7JME

Structure of the SARS-CoV-2 NSP3 Macro X domain in complex with cyclic AMP

Summary for 7JME

• Entry DOI: 10.2210/pdb7jme/pdb
• Descriptor: Non-structural protein 3, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE (3 entities in total)
• Functional Keywords: macro domain, camp, cyclic amp, viral protein, sars-cov-2, viral protein-inhibitor complex, viral protein/inhibitor
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2, COVID-19 virus)
• Total number of polymer chains: 1
• Total formula weight: 18823.31

Authors

Vuksanovic, N.,Melkonian, T.R.,Silvaggi, N.R. (deposition date: 2020-07-31, release date: 2020-09-02, Last modification date: 2023-10-18)

• Primary citation: Virdi, R.S.,Bavisotto, R.V.,Hopper, N.C.,Vuksanovic, N.,Melkonian, T.R.,Silvaggi, N.R.,Frick, D.N.; Discovery of Drug-Like Ligands for the Mac1 Domain of SARS-CoV-2 Nsp3.; Slas Discov, 25:1162-1170, 2020; PubMed: 32981460; DOI: 10.1177/2472555220960428

Experimental method

X-RAY DIFFRACTION (1.55 Å)