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Structure of HsICDH1:Mg(II):ICT:NADPH(50%) complex reveals structural basis for observation of half-sites reactivity
Descriptor:	FORMIC ACID, ISOCITRIC ACID, Isocitrate dehydrogenase [NADP] cytoplasmic, ...
Authors:	Silvaggi, N.R, Melkonian, T.R, Roman, J.V, Moran, G.R.
Deposit date:	2019-06-12
Release date:	2019-09-18
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (2.199 Å)
Cite:	Transient-State Analysis of Human Isocitrate Dehydrogenase I: Accounting for the Interconversion of Active and Non-Active Conformational States. Biochemistry, 58, 2019

Structure of the SARS-CoV-2 NSP3 Macro X domain in complex with cyclic AMP
Descriptor:	ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Non-structural protein 3
Authors:	Vuksanovic, N, Melkonian, T.R, Silvaggi, N.R.
Deposit date:	2020-07-31
Release date:	2020-09-02
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (1.55 Å)
Cite:	Discovery of Drug-Like Ligands for the Mac1 Domain of SARS-CoV-2 Nsp3. Slas Discov, 25, 2020

Structure of S. hygroscopicus aminotransferase MppQ complexed with pyridoxamine 5'-phosphate (PMP)
Descriptor:	4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, PLP-dependent aminotransferase MppQ
Authors:	Silvaggi, N.R, Vuksanovic, N.
Deposit date:	2023-08-01
Release date:	2023-11-22
Method:	X-RAY DIFFRACTION (1.63 Å)
Cite:	Structural and Biochemical Characterization of MppQ, an L-Enduracididine Biosynthetic Enzyme from Streptomyces hygroscopicus. Biochemistry, 62, 2023

Structure of S. hygroscopicus aminotransferase MppQ complexed with pyridoxal-5'-phosphate (PLP)
Descriptor:	PLP-dependent aminotransferase MppQ
Authors:	Silvaggi, N.R, Vuksanovic, N.
Deposit date:	2023-08-01
Release date:	2023-11-22
Method:	X-RAY DIFFRACTION (1.75 Å)
Cite:	Structural and Biochemical Characterization of MppQ, an L-Enduracididine Biosynthetic Enzyme from Streptomyces hygroscopicus. Biochemistry, 62, 2023