PDB: 2832 件ウェブページステータス検索Chemie searchBIRD

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4N84	Crystal structure of 14-3-3zeta in complex with a 12-carbon-linker cyclic peptide derived from ExoS 分子名称: 14-3-3 protein zeta/delta, Exoenzyme S 著者 Bier, D, Glas, A, Hahne, G, Grossmann, T, Ottmann, C. 登録日 2013-10-17 公開日 2014-02-19 最終更新日 2014-03-12 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Constrained peptides with target-adapted cross-links as inhibitors of a pathogenic protein-protein interaction. Angew.Chem.Int.Ed.Engl., 53, 2014
7ZH9	Uba1 in complex with ATP 分子名称: ACETATE ION, ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, ... 著者 Misra, M, Schindelin, H. 登録日 2022-04-05 公開日 2022-08-31 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Structures of UBA6 explain its dual specificity for ubiquitin and FAT10. Nat Commun, 13, 2022
3AU7	Crystal structure of the ZRD-deleted mutant of TiaS in complex with agmatine 分子名称: AGMATINE, Putative uncharacterized protein 著者 Numata, T, Osawa, T. 登録日 2011-01-31 公開日 2011-10-19 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural basis of tRNA agmatinylation essential for AUA codon decoding Nat.Struct.Mol.Biol., 18, 2011
4FJ3	14-3-3 isoform zeta in complex with a diphoyphorylated C-RAF peptide 分子名称: 14-3-3 protein zeta/delta, RAF proto-oncogene serine/threonine-protein kinase 著者 Ottmann, C, Molzan, M. 登録日 2012-06-11 公開日 2012-09-05 最終更新日 2013-07-10 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Synergistic binding of the phosphorylated S233- and S259-binding sites of C-RAF to one 14-3-3zeta dimer J.Mol.Biol., 423, 2012
2WH0	Recognition of an intrachain tandem 14-3-3 binding site within protein kinase C epsilon 分子名称: 14-3-3 PROTEIN ZETA/DELTA, CALCIUM ION, PROTEIN KINASE C EPSILON TYPE, ... 著者 Kostelecky, B, Saurin, A.T, Purkiss, A, Parker, P.J, McDonald, N.Q. 登録日 2009-04-28 公開日 2009-08-18 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Recognition of an Intra-Chain Tandem 14-3-3 Binding Site within Pkc Epsilon. Embo Rep., 10, 2009
3J78	Structures of yeast 80S ribosome-tRNA complexes in the rotated and non-rotated conformations (Class I - non-rotated ribosome with 2 tRNAs) 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0, ... 著者 Svidritskiy, E, Brilot, A.F, Koh, C.S, Grigorieff, N, Korostelev, A.A. 登録日 2014-05-29 公開日 2014-08-06 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (6.3 Å) 主引用文献 Structures of Yeast 80S Ribosome-tRNA Complexes in the Rotated and Nonrotated Conformations. Structure, 22, 2014
3J77	Structures of yeast 80S ribosome-tRNA complexes in the rotated and non-rotated conformations (Class II - rotated ribosome with 1 tRNA) 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0, ... 著者 Svidritskiy, E, Brilot, A.F, Koh, C.S, Grigorieff, N, Korostelev, A.A. 登録日 2014-05-29 公開日 2014-08-06 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (6.2 Å) 主引用文献 Structures of Yeast 80S Ribosome-tRNA Complexes in the Rotated and Nonrotated Conformations. Structure, 22, 2014
3J6Y	S. cerevisiae 80S ribosome bound with Taura syndrome virus (TSV) IRES, 2 degree rotation (Class I) 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0, ... 著者 Koh, C.S, Brilot, A.F, Grigorieff, N, Korostelev, A.A. 登録日 2014-04-16 公開日 2014-06-11 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (6.1 Å) 主引用文献 Taura syndrome virus IRES initiates translation by binding its tRNA-mRNA-like structural element in the ribosomal decoding center. Proc.Natl.Acad.Sci.USA, 111, 2014
3J6X	S. cerevisiae 80S ribosome bound with Taura syndrome virus (TSV) IRES, 5 degree rotation (Class II) 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0, ... 著者 Koh, C.S, Brilot, A.F, Grigorieff, N, Korostelev, A.A. 登録日 2014-04-16 公開日 2014-06-11 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (6.1 Å) 主引用文献 Taura syndrome virus IRES initiates translation by binding its tRNA-mRNA-like structural element in the ribosomal decoding center. Proc.Natl.Acad.Sci.USA, 111, 2014
5OK6	Ubiquitin specific protease 11 USP11 - peptide F complex 分子名称: 1,2-ETHANEDIOL, ALA-GLU-GLY-GLU-PHE-TYR-LYS-LEU-LYS-ILE-ARG-THR-PRO-AAR, GLYCEROL, ... 著者 Spiliotopoulos, A, Dreveny, I. 登録日 2017-07-25 公開日 2018-08-08 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Discovery of peptide ligands targeting a specific ubiquitin-like domain-binding site in the deubiquitinase USP11. J.Biol.Chem., 294, 2019
4HKC	14-3-3-zeta in complex with S1011 phosphorylated integrin alpha-4 peptide 分子名称: 14-3-3 protein zeta/delta, GLYCEROL, alpha-4 integrin derived phosphorylated peptide 著者 Bonet, R, Campbell, I.D. 登録日 2012-10-15 公開日 2013-06-26 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Characterization of 14-3-3-zeta Interactions with integrin tails J.Mol.Biol., 425, 2013
4PJ1	Crystal structure of the human mitochondrial chaperonin symmetrical 'football' complex 分子名称: 10 kDa heat shock protein, mitochondrial, 60 kDa heat shock protein, ... 著者 Frolow, F, Azem, A, Nisemblat, S. 登録日 2014-05-10 公開日 2015-04-29 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Crystal structure of the human mitochondrial chaperonin symmetrical football complex. Proc.Natl.Acad.Sci.USA, 112, 2015
4NNJ	Crystal structure of Uba1 in complex with ubiquitin-AMP and thioesterified ubiquitin 分子名称: ADENOSINE MONOPHOSPHATE, GLYCEROL, SULFATE ION, ... 著者 Schaefer, A, Schindelin, H. 登録日 2013-11-18 公開日 2014-05-07 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure of the ubiquitin-activating enzyme loaded with two ubiquitin molecules. Acta Crystallogr.,Sect.D, 70, 2014
1ADI	STRUCTURE OF ADENYLOSUCCINATE SYNTHETASE AT PH 6.5 AND 25 DEGREES CELSIUS 分子名称: ADENYLOSUCCINATE SYNTHETASE 著者 Silva, M.M, Poland, B.W, Hoffman, C.M, Fromm, H.J, Honzatko, R.B. 登録日 1995-09-14 公開日 1996-06-10 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Refined crystal structures of unligated adenylosuccinate synthetase from Escherichia coli. J.Mol.Biol., 254, 1995
6G4S	Cryo-EM structure of a late human pre-40S ribosomal subunit - State B 分子名称: 40S ribosomal protein S11, 40S ribosomal protein S13, 40S ribosomal protein S14, ... 著者 Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R. 登録日 2018-03-28 公開日 2018-06-06 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Visualizing late states of human 40S ribosomal subunit maturation. Nature, 558, 2018
6G4W	Cryo-EM structure of a late human pre-40S ribosomal subunit - State A 分子名称: 18S ribosomal RNA, 40S ribosomal protein S11, 40S ribosomal protein S13, ... 著者 Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R. 登録日 2018-03-28 公開日 2018-06-06 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Visualizing late states of human 40S ribosomal subunit maturation. Nature, 558, 2018
5APN	Structure of the yeast 60S ribosomal subunit in complex with Arx1, Alb1 and N-terminally tagged Rei1 分子名称: 25S rRNA, 5.8S rRNA, 5S rRNA, ... 著者 Greber, B.J, Gerhardy, S, Leitner, A, Leibundgut, M, Salem, M, Boehringer, D, Leulliot, N, Aebersold, R, Panse, V.G, Ban, V. 登録日 2015-09-17 公開日 2015-12-16 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.91 Å) 主引用文献 Insertion of the Biogenesis Factor Rei1 Probes the Ribosomal Tunnel during 60S Maturation. Cell, 164, 2015
4I2W	Crystal structure of the myosin chaperone UNC-45 from C.elegans in complex with a Hsp70 peptide 分子名称: Heat shock 70 kDa protein A, Protein UNC-45 著者 Clausen, T, Gazda, L, Hellerschmied, D. 登録日 2012-11-23 公開日 2013-03-13 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 The myosin chaperone UNC-45 is organized in tandem modules to support myofilament formation in C. elegans. Cell(Cambridge,Mass.), 152, 2013
8AH2	Crystal structure of human 14-3-3 zeta fused to the NPM1 peptide including phosphoserine-48 分子名称: 14-3-3 protein zeta/delta,Nucleophosmin 著者 Boyko, K.M, Kapitonova, A.A, Tugaeva, K.V, Varfolomeeva, L.A, Sluchanko, N.N. 登録日 2022-07-20 公開日 2022-09-14 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural basis for the recognition by 14-3-3 proteins of a conditional binding site within the oligomerization domain of human nucleophosmin. Biochem.Biophys.Res.Commun., 627, 2022
6FNB	Mono- and bivalent 14-3-3 inhibitors for characterizing supramolecular lysine-PEG interactions in proteins 分子名称: 14-3-3 protein zeta/delta, BENZOIC ACID, CALCIUM ION, ... 著者 Bier, D, Ottmann, C. 登録日 2018-02-02 公開日 2018-07-04 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Mono- and Bivalent 14-3-3 Inhibitors for Characterizing Supramolecular "Lysine Wrapping" of Oligoethylene Glycol (OEG) Moieties in Proteins. Chemistry, 24, 2018
1R0E	Glycogen synthase kinase-3 beta in complex with 3-indolyl-4-arylmaleimide inhibitor 分子名称: 3-[3-(2,3-DIHYDROXY-PROPYLAMINO)-PHENYL]-4-(5-FLUORO-1-METHYL-1H-INDOL-3-YL)-PYRROLE-2,5-DIONE, CITRATE ANION, Glycogen synthase kinase-3 beta 著者 Allard, J, Nikolcheva, T, Gong, L, Wang, J, Dunten, P, Avnur, Z, Waters, R, Sun, Q, Skinner, B. 登録日 2003-09-20 公開日 2004-10-12 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 From genetics to therapeutics: the Wnt pathway and osteoporosis To be Published
1QJA	14-3-3 ZETA/PHOSPHOPEPTIDE COMPLEX (MODE 2) 分子名称: 14-3-3 PROTEIN ZETA, PHOSPHOPEPTIDE 著者 Rittinger, K, Budman, J, Xu, J, Volinia, S, Cantley, L.C, Smerdon, S.J, Gamblin, S.J, Yaffe, M.B. 登録日 1999-06-23 公開日 1999-09-15 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural Analysis of 14-3-3 Phosphopeptide Complexes Identifies a Dual Role for the Nuclear Export Signal of 14-3-3 in Ligand Binding Mol.Cell, 4, 1999
6GJO	Crystal Structure of Glycogen Synthase Kinase-3 beta in Complex with BI-91BS 分子名称: (3~{Z})-5-ethanoyl-3-[[(1-methylpiperidin-4-yl)amino]-phenyl-methylidene]-1~{H}-indol-2-one, Glycogen synthase kinase-3 beta 著者 Hoerer, S. 登録日 2018-05-16 公開日 2019-03-27 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (2.91 Å) 主引用文献 CRYSTAL STRUCTURE OF Glycogen synthase kinase-3 beta IN COMPLEX WITH BI-91BS To Be Published
6H0U	Glycogen synthase kinase-3 beta (GSK3) complex with a covalent [1,2,4]triazolo[1,5-a][1,3,5]triazine inhibitor 分子名称: (2~{R})-3-[7-azanyl-5-(cyclohexylamino)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-2-yl]-2-cyano-propanamide, CHLORIDE ION, GLYCEROL, ... 著者 Marcovich, I, Demitri, N, De Zorzi, R, Storici, P. 登録日 2018-07-10 公開日 2019-05-15 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 A Triazolotriazine-Based Dual GSK-3 beta /CK-1 delta Ligand as a Potential Neuroprotective Agent Presenting Two Different Mechanisms of Enzymatic Inhibition. Chemmedchem, 14, 2019
5EWZ	Small-molecule stabilization of the 14-3-3/Gab2 PPI interface 分子名称: 14-3-3 protein zeta/delta, BENZOIC ACID, GRB2-associated-binding protein 2 著者 Bier, D, Ottmann, C. 登録日 2015-11-23 公開日 2016-05-04 最終更新日 2018-12-19 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 Small-Molecule Stabilization of the 14-3-3/Gab2 Protein-Protein Interaction (PPI) Interface. Chemmedchem, 11, 2016

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