1R0E
Glycogen synthase kinase-3 beta in complex with 3-indolyl-4-arylmaleimide inhibitor
Summary for 1R0E
Entry DOI | 10.2210/pdb1r0e/pdb |
Related | 1H8F |
Descriptor | Glycogen synthase kinase-3 beta, CITRATE ANION, 3-[3-(2,3-DIHYDROXY-PROPYLAMINO)-PHENYL]-4-(5-FLUORO-1-METHYL-1H-INDOL-3-YL)-PYRROLE-2,5-DIONE, ... (4 entities in total) |
Functional Keywords | ser/thr protein kinase, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P49841 |
Total number of polymer chains | 2 |
Total formula weight | 88394.32 |
Authors | Allard, J.,Nikolcheva, T.,Gong, L.,Wang, J.,Dunten, P.,Avnur, Z.,Waters, R.,Sun, Q.,Skinner, B. (deposition date: 2003-09-20, release date: 2004-10-12, Last modification date: 2023-08-23) |
Primary citation | Allard, J.,Nikolcheva, T.,Gong, L.,Wang, J.,Dunten, P.,Avnur, Z.,Waters, R.,Sun, Q.,Skinner, B. From genetics to therapeutics: the Wnt pathway and osteoporosis To be Published, |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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