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1R0E

Glycogen synthase kinase-3 beta in complex with 3-indolyl-4-arylmaleimide inhibitor

Summary for 1R0E
Entry DOI10.2210/pdb1r0e/pdb
Related1H8F
DescriptorGlycogen synthase kinase-3 beta, CITRATE ANION, 3-[3-(2,3-DIHYDROXY-PROPYLAMINO)-PHENYL]-4-(5-FLUORO-1-METHYL-1H-INDOL-3-YL)-PYRROLE-2,5-DIONE, ... (4 entities in total)
Functional Keywordsser/thr protein kinase, transferase
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm: P49841
Total number of polymer chains2
Total formula weight88394.32
Authors
Allard, J.,Nikolcheva, T.,Gong, L.,Wang, J.,Dunten, P.,Avnur, Z.,Waters, R.,Sun, Q.,Skinner, B. (deposition date: 2003-09-20, release date: 2004-10-12, Last modification date: 2023-08-23)
Primary citationAllard, J.,Nikolcheva, T.,Gong, L.,Wang, J.,Dunten, P.,Avnur, Z.,Waters, R.,Sun, Q.,Skinner, B.
From genetics to therapeutics: the Wnt pathway and osteoporosis
To be Published,
Experimental method
X-RAY DIFFRACTION (2.25 Å)
Structure validation

217705

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