1R0E
Glycogen synthase kinase-3 beta in complex with 3-indolyl-4-arylmaleimide inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Glycogen synthase kinase-3 beta | polymer | 391 | 43598.7 | 2 | UniProt (P49841) Pfam (PF00069) | Homo sapiens (human) | GSK-3 beta |
| 2 | C, E (A, B) | CITRATE ANION | non-polymer | 189.1 | 2 | Chemie (FLC) | |||
| 3 | D, F (A, B) | 3-[3-(2,3-DIHYDROXY-PROPYLAMINO)-PHENYL]-4-(5-FLUORO-1-METHYL-1H-INDOL-3-YL)-PYRROLE-2,5-DIONE | non-polymer | 409.4 | 2 | Chemie (DFN) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 185 | Chemie (HOH) |
Sequence modifications
A, B: 35 - 420 (UniProt: P49841)
| PDB | External Database | Details |
|---|---|---|
| Gly 30 | - | cloning artifact |
| Ala 31 | - | cloning artifact |
| Met 32 | - | cloning artifact |
| Ser 33 | - | cloning artifact |
| Leu 34 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 87197.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1197.0 | |
| All* | Total formula weight | 88394.3 |
