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1Z81
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Crystal Structure of cyclophilin from Plasmodium yoelii.
分子名称: cyclophilin
著者Mulichak, A, Alam, Z, Amani, M, Lew, J, Wasney, G, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Hui, R, Vedadi, M, Structural Genomics Consortium (SGC)
登録日2005-03-29
公開日2005-04-05
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007
1Z7D
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Ornithine aminotransferase PY00104 from Plasmodium Yoelii
分子名称: ornithine aminotransferase
著者Walker, J.R, Alam, Z, Amani, M, Lew, J, Wasney, G, Boulanger, K, Weigelt, J, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Hui, R, Vedadi, M, Structural Genomics Consortium (SGC)
登録日2005-03-24
公開日2005-07-07
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007
1CTM
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CRYSTAL STRUCTURE OF CHLOROPLAST CYTOCHROME F REVEALS A NOVEL CYTOCHROME FOLD AND UNEXPECTED HEME LIGATION
分子名称: CYTOCHROME F, HEME C
著者Martinez, S.E, Huang, D, Szczepaniak, A, Cramer, W.A, Smith, J.L.
登録日1994-01-02
公開日1994-05-31
最終更新日2021-03-10
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of chloroplast cytochrome f reveals a novel cytochrome fold and unexpected heme ligation.
Structure, 2, 1994
1HCZ
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LUMEN-SIDE DOMAIN OF REDUCED CYTOCHROME F AT-35 DEGREES CELSIUS
分子名称: CYTOCHROME F, PROTOPORPHYRIN IX CONTAINING FE
著者Martinez, S.E, Huang, D, Szczepaniak, A, Cramer, W.A, Smith, J.L.
登録日1996-09-18
公開日1997-03-12
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献The heme redox center of chloroplast cytochrome f is linked to a buried five-water chain.
Protein Sci., 5, 1996
2PCF
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THE COMPLEX OF CYTOCHROME F AND PLASTOCYANIN DETERMINED WITH PARAMAGNETIC NMR. BASED ON THE STRUCTURES OF CYTOCHROME F AND PLASTOCYANIN, 10 STRUCTURES
分子名称: COPPER (II) ION, CYTOCHROME F, HEME C, ...
著者Ubbink, M, Ejdeback, M, Karlsson, B.G, Bendall, D.S.
登録日1997-12-22
公開日1998-04-08
最終更新日2022-03-16
実験手法SOLUTION NMR
主引用文献The structure of the complex of plastocyanin and cytochrome f, determined by paramagnetic NMR and restrained rigid-body molecular dynamics.
Structure, 6, 1998
1TKW
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The transient complex of poplar plastocyanin with turnip cytochrome f determined with paramagnetic NMR
分子名称: COPPER (II) ION, Cytochrome f, HEME C, ...
著者Lange, C, Cornvik, T, Diaz-Moreno, I, Ubbink, M.
登録日2004-06-09
公開日2005-05-24
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献The transient complex of poplar plastocyanin with cytochrome f: effects of ionic strength and pH
Biochim.Biophys.Acta, 1707, 2005
2V1W
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BU of 2v1w by Molmil
Crystal structure of human LIM protein RIL (PDLIM4) PDZ domain bound to the C-terminal peptide of human alpha-actinin-1
分子名称: 1,2-ETHANEDIOL, MAGNESIUM ION, PDZ AND LIM DOMAIN PROTEIN 4, ...
著者Soundararajan, M, Shrestha, L, Pike, A.C.W, Salah, E, Burgess-Brown, N, Elkins, J, Umeano, C, Ugochukwu, E, von Delft, F, Arrowsmith, C.H, Edwards, A, Weigelt, J, Sundstrom, M, Doyle, D.
登録日2007-05-30
公開日2007-06-12
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Unusual Binding Interactions in Pdz Domain Crystal Structures Help Explain Binding Mechanisms.
Protein Sci., 19, 2010
7WQQ
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Retinoic acid receptor alpha mutant - N299H
分子名称: 4-[(E)-3-(3,5-ditert-butylphenyl)-3-oxidanylidene-prop-1-enyl]benzoic acid, Peptide from Nuclear receptor coactivator 1, Retinoic acid receptor alpha
著者Huang, X.X, Ng, L.M, Teh, B.T.
登録日2022-01-25
公開日2023-01-25
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Effects of breast fibroepithelial tumor associated retinoic acid receptor alpha ligand binding domain mutations on receptor function and retinoid signaling
To Be Published
4DQM
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Revealing a marine natural product as a novel agonist for retinoic acid receptors with a unique binding mode and antitumor activity
分子名称: (5S)-4-[(3E,7E)-4,8-dimethyl-10-(2,6,6-trimethylcyclohex-1-en-1-yl)deca-3,7-dien-1-yl]-5-hydroxyfuran-2(5H)-one, Nuclear receptor coactivator 1, Retinoic acid receptor alpha
著者Wang, S, Wang, Z, Lin, S, Zheng, W, Wang, R, Jin, S, Chen, J, Jin, L, Li, Y.
登録日2012-02-16
公開日2012-10-03
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Revealing a natural marine product as a novel agonist for retinoic acid receptors with a unique binding mode and inhibitory effects on cancer cells.
Biochem.J., 446, 2012
3A9E
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Crystal structure of a mixed agonist-bound RAR-alpha and antagonist-bound RXR-alpha heterodimer ligand binding domains
分子名称: (2E,4E,6Z)-3-methyl-7-(5,5,8,8-tetramethyl-3-propoxy-5,6,7,8-tetrahydronaphthalen-2-yl)octa-2,4,6-trienoic acid, 13-mer (LXXLL motif) from Nuclear receptor coactivator 2, RETINOIC ACID, ...
著者Sato, Y, Duclaud, S, Peluso-Iltis, C, Poussin, P, Moras, D, Rochel, N, Structural Proteomics in Europe (SPINE)
登録日2009-10-24
公開日2010-10-06
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献The Phantom Effect of the Rexinoid LG100754: structural and functional insights
Plos One, 5, 2010
6XWG
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BU of 6xwg by Molmil
Crystal Structure of the Human RXR/RAR DNA-Binding Domain Heterodimer Bound to the Human RARb2 DR5 Response Element
分子名称: CHLORIDE ION, GLYCEROL, RARb2 DR5 Response Element, ...
著者McEwen, A.G, Poussin-Courmontagne, P, Peluso-Iltis, C, Rochel, N.
登録日2020-01-23
公開日2020-09-09
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for DNA recognition and allosteric control of the retinoic acid receptors RAR-RXR.
Nucleic Acids Res., 48, 2020
5K13
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Crystal structure of the RAR alpha ligand-binding domain in complex with an antagonist
分子名称: 4-{5-(3-tert-butylphenyl)-1-[4-(methylsulfonyl)phenyl]-1H-pyrazol-3-yl}benzoic acid, Retinoic acid receptor alpha
著者Wang, Y, Stout, S.L.
登録日2016-05-17
公開日2016-06-22
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Identification of potent and selective retinoic acid receptor gamma (RAR gamma ) antagonists for the treatment of osteoarthritis pain using structure based drug design.
Bioorg.Med.Chem.Lett., 26, 2016
5YUF
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BU of 5yuf by Molmil
Crystal Structure of PML RING tetramer
分子名称: Protein PML, ZINC ION
著者Wang, P, Benhend, S, Wu, H, Breitenbach, V, Zhen, T, Jollivet, F, Peres, L, Li, Y, Chen, S, Chen, Z, de THE, H, Meng, G.
登録日2017-11-22
公開日2018-04-11
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献RING tetramerization is required for nuclear body biogenesis and PML sumoylation.
Nat Commun, 9, 2018
1DSZ
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STRUCTURE OF THE RXR/RAR DNA-BINDING DOMAIN HETERODIMER IN COMPLEX WITH THE RETINOIC ACID RESPONSE ELEMENT DR1
分子名称: DNA (5'-D(*CP*AP*GP*GP*TP*CP*AP*AP*AP*GP*GP*TP*CP*AP*G)-3'), DNA (5'-D(*CP*TP*GP*AP*CP*CP*TP*TP*TP*GP*AP*CP*CP*TP*G)-3'), RETINOIC ACID RECEPTOR ALPHA, ...
著者Rastinejad, F, Wagner, T, Zhao, Q, Khorasanizadeh, S.
登録日2000-01-10
公開日2000-07-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure of the RXR-RAR DNA-binding complex on the retinoic acid response element DR1.
EMBO J., 19, 2000
3IQ3
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Crystal Structure of Bothropstoxin-I complexed with polietilene glicol 4000 - crystallized at 283 K
分子名称: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Phospholipase A2 homolog bothropstoxin-1, SULFATE ION
著者Salvador, G.H.M, Marchi-Salvador, D.P, Silva, M.C.O, Soares, A.M, Fontes, M.R.M.
登録日2009-08-19
公開日2009-10-27
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Comparison between apo and complexed structures of bothropstoxin-I reveals the role of Lys122 and Ca(2+)-binding loop region for the catalytically inactive Lys49-PLA(2)s.
J.Struct.Biol., 171, 2010
3I3I
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Crystal Structure of Bothropstoxin-I crystallized at 283 K
分子名称: Phospholipase A2 homolog bothropstoxin-1
著者Salvador, G.H.M, Marchi-Salvador, D.P, Soares, A.M, Fontes, M.R.M.
登録日2009-06-30
公開日2010-04-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Comparison between apo and complexed structures of bothropstoxin-I reveals the role of Lys122 and Ca(2+)-binding loop region for the catalytically inactive Lys49-PLA(2)s.
J.Struct.Biol., 171, 2010
6DIK
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Crystal structure of Bothropstoxin I (BthTX-I) complexed to Chicoric acid
分子名称: (2R,3R)-2,3-bis{[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}butanedioic acid, BICARBONATE ION, Basic phospholipase A2 homolog bothropstoxin-1, ...
著者Cardoso, F.F, Salvador, G.H.M, Borges, R.J.
登録日2018-05-23
公開日2018-10-03
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Structural basis of phospholipase A2-like myotoxin inhibition by chicoric acid, a novel potent inhibitor of ophidian toxins.
Biochim Biophys Acta Gen Subj, 1862, 2018
1IJK
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The von Willebrand Factor mutant (I546V) A1 domain-botrocetin Complex
分子名称: Botrocetin, von Willebrand factor
著者Fukuda, K, Doggett, T.A, Bankston, L.A, Cruz, M.A, Diacovo, T.G, Liddington, R.C.
登録日2001-04-26
公開日2002-07-10
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis of von Willebrand factor activation by the snake toxin botrocetin.
Structure, 10, 2002
4WTB
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BthTX-I, a svPLA2s-like toxin, complexed with zinc ions
分子名称: Basic phospholipase A2 homolog bothropstoxin-1, CHLORIDE ION, SULFATE ION, ...
著者Borges, R.J, Fontes, M.R.M.
登録日2014-10-29
公開日2015-11-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Functional and structural studies of a Phospholipase A2-like protein complexed to zinc ions: Insights on its myotoxicity and inhibition mechanism.
Biochim. Biophys. Acta, 1861, 2017
3CXI
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Structure of BthTX-I complexed with alpha-tocopherol
分子名称: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Myotoxic phospholipase A2-like, SULFATE ION, ...
著者dos Santos, J.I, Fontes, M.R.M.
登録日2008-04-24
公開日2009-05-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Comparative structural studies on Lys49-phospholipases A(2) from Bothrops genus reveal their myotoxic site.
J.Struct.Biol., 167, 2009
1U0N
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The ternary von Willebrand Factor A1-glycoprotein Ibalpha-botrocetin complex
分子名称: Botrocetin, Platelet glycoprotein Ib, Von Willebrand factor
著者Fukuda, K, Liddington, R.C.
登録日2004-07-13
公開日2005-04-19
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献The snake venom protein botrocetin acts as a biological brace to promote dysfunctional platelet aggregation
Nat.Struct.Mol.Biol., 12, 2005
1U0O
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The mouse von Willebrand Factor A1-botrocetin complex
分子名称: Botrocetin, von Willebrand factor
著者Fukuda, K, Liddington, R.C.
登録日2004-07-14
公開日2005-04-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The snake venom protein botrocetin acts as a biological brace to promote dysfunctional platelet aggregation
Nat.Struct.Mol.Biol., 12, 2005
2H8I
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Crystal Structure of the Bothropstoxin-I complexed with polyethylene glycol
分子名称: DI(HYDROXYETHYL)ETHER, Phospholipase A2 homolog 1
著者Murakami, M.T, Arni, R.K.
登録日2006-06-07
公開日2007-06-19
最終更新日2022-12-21
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Interfacial surface charge and free accessibility to the PLA2-active site-like region are essential requirements for the activity of Lys49 PLA2 homologues
Toxicon, 49, 2007
3I03
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Crystal structure of bothropstoxin-I chemically modified by p-bromophenacyl bromide (BPB) - monomeric form at a high resolution
分子名称: ISOPROPYL ALCOHOL, Phospholipase A2 homolog bothropstoxin-1, p-Bromophenacyl bromide
著者Marchi-Salvador, D.P, Fernandes, C.A.H, Soares, A.M, Fontes, M.R.M.
登録日2009-06-24
公開日2010-05-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Comparison between apo and complexed structures of bothropstoxin-I reveals the role of Lys122 and Ca(2+)-binding loop region for the catalytically inactive Lys49-PLA(2)s.
J.Struct.Biol., 171, 2010
3HZW
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Crystal structure of bothropstoxin-I chemically modified by p-bromophenacyl bromide (BPB)
分子名称: ISOPROPYL ALCOHOL, Phospholipase A2 homolog bothropstoxin-1, p-Bromophenacyl bromide
著者Fernandes, C.A.H, Marchi-Salvador, D.P, Soares, A.M, Fontes, M.R.M.
登録日2009-06-24
公開日2010-05-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Comparison between apo and complexed structures of bothropstoxin-I reveals the role of Lys122 and Ca(2+)-binding loop region for the catalytically inactive Lys49-PLA(2)s.
J.Struct.Biol., 171, 2010

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