3I03
Crystal structure of bothropstoxin-I chemically modified by p-bromophenacyl bromide (BPB) - monomeric form at a high resolution
Summary for 3I03
Entry DOI | 10.2210/pdb3i03/pdb |
Related | 1Y4L 2Q2J 3CXI 3CYL 3HZD 3HZW |
Descriptor | Phospholipase A2 homolog bothropstoxin-1, p-Bromophenacyl bromide, ISOPROPYL ALCOHOL, ... (4 entities in total) |
Functional Keywords | lys49-pla2s, phospholipase homologue, bothropstoxin-i, p-bromophenacyl bromide, myotoxicity, antibiotic, antimicrobial, disulfide bond, myotoxin, secreted, toxin |
Biological source | Bothrops jararacussu (snake) |
Total number of polymer chains | 1 |
Total formula weight | 14091.17 |
Authors | Marchi-Salvador, D.P.,Fernandes, C.A.H.,Soares, A.M.,Fontes, M.R.M. (deposition date: 2009-06-24, release date: 2010-05-12, Last modification date: 2023-09-06) |
Primary citation | Fernandes, C.A.,Marchi-Salvador, D.P.,Salvador, G.M.,Silva, M.C.,Costa, T.R.,Soares, A.M.,Fontes, M.R. Comparison between apo and complexed structures of bothropstoxin-I reveals the role of Lys122 and Ca(2+)-binding loop region for the catalytically inactive Lys49-PLA(2)s. J.Struct.Biol., 171:31-43, 2010 Cited by PubMed: 20371382DOI: 10.1016/j.jsb.2010.03.019 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.48 Å) |
Structure validation
Download full validation report