PDB: 292 件ウェブページステータス検索Chemie searchBIRD

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4R11	A conserved phosphorylation switch controls the interaction between cadherin and beta-catenin in vitro and in vivo 分子名称: Cadherin-related hmr-1, IODIDE ION, Protein humpback-2 著者 Choi, H.-J, Loveless, T, Lynch, A, Bang, I, Hardin, J, Weis, W.I. 登録日 2014-08-03 公開日 2015-04-29 実験手法 X-RAY DIFFRACTION (2.789 Å) 主引用文献 A Conserved Phosphorylation Switch Controls the Interaction between Cadherin and beta-Catenin In Vitro and In Vivo Dev.Cell, 33, 2015
4R10	A conserved phosphorylation switch controls the interaction between cadherin and beta-catenin in vitro and in vivo 分子名称: 1,2-ETHANEDIOL, Cadherin-related hmr-1, Protein humpback-2, ... 著者 Choi, H.-J, Loveless, T, Lynch, A, Bang, I, Hardin, J, Weis, W.I. 登録日 2014-08-03 公開日 2015-04-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 A Conserved Phosphorylation Switch Controls the Interaction between Cadherin and beta-Catenin In Vitro and In Vivo Dev.Cell, 33, 2015
4RXH	Crystal Structure of Importin-alpha from Neurospora crassa complexed with SV40NLS 分子名称: Importin subunit alpha, Large T antigen 著者 Bernardes, N.E, Takeda, A.A.S, Fontes, M.R.M. 登録日 2014-12-11 公開日 2015-07-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.7553 Å) 主引用文献 Structure of Importin-alpha from a Filamentous Fungus in Complex with a Classical Nuclear Localization Signal. Plos One, 10, 2015
4TNM	Crystal structure of Arabidopsis importin-alpha3 armadillo repeat domain 分子名称: Importin subunit alpha 著者 Wirthmueller, L, Banfield, M. 登録日 2014-06-04 公開日 2014-10-08 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Probing formation of cargo/importin-alpha transport complexes in plant cells using a pathogen effector. Plant J., 81, 2015
4U2X	Ebola virus VP24 in complex with Karyopherin alpha 5 C-terminus 分子名称: CHLORIDE ION, Importin subunit alpha-6, Membrane-associated protein VP24 著者 Xu, W, Leung, D, Borek, D, Amarasinghe, G. 登録日 2014-07-18 公開日 2014-08-13 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3.153 Å) 主引用文献 Ebola Virus VP24 Targets a Unique NLS Binding Site on Karyopherin Alpha 5 to Selectively Compete with Nuclear Import of Phosphorylated STAT1. Cell Host Microbe, 16, 2014
4U58	IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR 分子名称: Importin subunit alpha-1, N~2~-[4-(pyridin-3-yl)benzoyl]-L-lysinamide 著者 Stewart, M, Valkov, E, Holvey, R.S. 登録日 2014-07-24 公開日 2015-05-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.56 Å) 主引用文献 Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design. Chemmedchem, 10, 2015
4U5O	IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR 分子名称: Importin subunit alpha-1, N~2~-[4-(pyridin-3-yl)benzyl]-D-lysinamide 著者 Stewart, M, Valkov, E, Holvey, R.S. 登録日 2014-07-25 公開日 2015-05-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design. Chemmedchem, 10, 2015
4UAE	Importin alpha 3 delta IBB in complex with Influenza PB2 Nuclear Localization Domain 分子名称: Importin subunit alpha-3, Polymerase basic protein 2, SULFATE ION 著者 Pumroy, R.A, Cingolani, G. 登録日 2014-08-08 公開日 2015-02-04 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Molecular Determinants for Nuclear Import of Influenza A PB2 by Importin alpha Isoforms 3 and 7. Structure, 23, 2015
4UAD	Importin alpha 7 delta IBB in complex with Influenza PB2 Nuclear Localization Domain 分子名称: Importin subunit alpha-7, Polymerase basic protein 2 著者 Pumroy, R.A, Cingolani, G. 登録日 2014-08-08 公開日 2015-02-04 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.42 Å) 主引用文献 Molecular Determinants for Nuclear Import of Influenza A PB2 by Importin alpha Isoforms 3 and 7. Structure, 23, 2015
4U5N	IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR 分子名称: Importin subunit alpha-1, N~2~-[4-(pyridin-3-yl)benzyl]-L-lysyl-N-[(1R,2S,3R)-1-{[(2R)-1-amino-1-oxo-3-phenylpropan-2-yl]amino}-1,3-dihydroxybutan-2-yl]glycinamide 著者 Stewart, M, Valkov, E, Holvey, R.S. 登録日 2014-07-25 公開日 2015-05-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design. Chemmedchem, 10, 2015
4U5S	IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR 分子名称: Importin subunit alpha-1, N-[(2S)-2-[(N~2~-acetyl-D-lysyl)amino]-3-(pyridin-3-ylmethoxy)propyl]-L-allothreonyl-D-phenylalaninamide 著者 Stewart, M, Valkov, E, Holvey, R.S. 登録日 2014-07-25 公開日 2015-05-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design. Chemmedchem, 10, 2015
4U54	IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR 分子名称: Importin subunit alpha-1, N-methyl-1-[3-(pyridin-3-yl)phenyl]methanamine 著者 Stewart, M, Valkov, E, Holvey, R.S. 登録日 2014-07-24 公開日 2015-05-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.41 Å) 主引用文献 Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design. Chemmedchem, 10, 2015
4U5U	IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR 分子名称: Importin subunit alpha-1, N~2~-[3-(pyridin-3-yl)benzyl]-L-lysinamide 著者 Stewart, M, Valkov, E, Holvey, R.S. 登録日 2014-07-25 公開日 2015-05-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design. Chemmedchem, 10, 2015
4UAF	Importin alpha 1 delta IBB in complex with Influenza PB2 nuclear localization domain 分子名称: Importin subunit alpha-1, PHOSPHATE ION, Polymerase basic protein 2 著者 Pumroy, R.A, Cingolani, G. 登録日 2014-08-08 公開日 2015-02-04 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.698 Å) 主引用文献 Molecular Determinants for Nuclear Import of Influenza A PB2 by Importin alpha Isoforms 3 and 7. Structure, 23, 2015
4U5L	IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR 分子名称: Importin subunit alpha-1, N~2~-[4-(pyridin-3-yl)benzyl]-L-lysinamide 著者 Stewart, M, Valkov, E, Holvey, R.S. 登録日 2014-07-25 公開日 2015-05-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.53 Å) 主引用文献 Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design. Chemmedchem, 10, 2015
4U5V	IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR 分子名称: Importin subunit alpha-1, N~2~-{[5-(pyridin-3-yl)thiophen-2-yl]methyl}-L-lysinamide 著者 Stewart, M, Valkov, E, Holvey, R.S. 登録日 2014-07-25 公開日 2015-05-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.968 Å) 主引用文献 Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design. Chemmedchem, 10, 2015
3TPO	Crystal structure of D192A/E396A mutant of mouse importin alpha2 分子名称: Importin subunit alpha-2 著者 Hirano, H, Matsuura, Y. 登録日 2011-09-08 公開日 2011-10-12 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Sensing actin dynamics: structural basis for G-actin-sensitive nuclear import of MAL Biochem.Biophys.Res.Commun., 414, 2011
8F2Q	Human Parvovirus B19 Nonstructural NS1 Protein NLS bound to Importin Alpha 2 分子名称: Importin subunit alpha-1, Initiator protein NS1 著者 Cross, E.M, Forwood, J.K. 登録日 2022-11-08 公開日 2023-05-03 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Importin alpha / beta-dependent nuclear transport of human parvovirus B19 nonstructural protein 1 is essential for viral replication. Antiviral Res., 213, 2023
3SL9	X-ray structure of Beta catenin in complex with Bcl9 分子名称: 1,2-ETHANEDIOL, B-cell CLL/lymphoma 9 protein, Catenin beta-1, ... 著者 Gupta, D, Bienz, M. 登録日 2011-06-24 公開日 2012-02-29 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 An intrinsically labile alpha-helix abutting the BCL9-binding site of beta-catenin is required for its inhibition by carnosic acid. Nat Commun, 3, 2012
8EI9	Crystal structure of beta-catenin and the MDM2 p53-binding domain in complex with H332, a Helicon Polypeptide 分子名称: Catenin beta-1, E3 ubiquitin-protein ligase Mdm2, H332, ... 著者 Li, K, Travaline, T.L, Swiecicki, J.-M, Tokareva, O.S, Thomson, T.M, Verdine, G.L, McGee, J.H. 登録日 2022-09-14 公開日 2023-10-25 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (3.9 Å) 主引用文献 Recognition and reprogramming of E3 ubiquitin ligase surfaces by alpha-helical peptides. Nat Commun, 14, 2023
8EIC	Crystal structure of beta-catenin and the MDM2 p53-binding domain in complex with H330, a Helicon Polypeptide 分子名称: Catenin beta-1, E3 ubiquitin-protein ligase Mdm2, H330, ... 著者 Li, K, Travaline, T.L, Swiecicki, J.-M, Tokareva, O.S, Thomson, T.M, Verdine, G.L, McGee, J.H. 登録日 2022-09-14 公開日 2023-10-25 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.62 Å) 主引用文献 Recognition and reprogramming of E3 ubiquitin ligase surfaces by alpha-helical peptides. Nat Commun, 14, 2023
8EIB	Crystal structure of beta-catenin and the MDM2 p53-binding domain in complex with H329, a Helicon Polypeptide 分子名称: Catenin beta-1, E3 ubiquitin-protein ligase Mdm2, H329, ... 著者 Li, K, Travaline, T.L, Swiecicki, J.-M, Tokareva, O.S, Thomson, T.M, Verdine, G.L, McGee, J.H. 登録日 2022-09-14 公開日 2023-10-25 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (3.76 Å) 主引用文献 Recognition and reprogramming of E3 ubiquitin ligase surfaces by alpha-helical peptides. Nat Commun, 14, 2023
8EIA	Crystal structure of beta-catenin and the MDM2 p53-binding domain in complex with H333, a Helicon Polypeptide 分子名称: Catenin beta-1, E3 ubiquitin-protein ligase Mdm2, H333, ... 著者 Li, K, Travaline, T.L, Swiecicki, J.-M, Tokareva, O.S, Thomson, T.M, Verdine, G.L, McGee, J.H. 登録日 2022-09-14 公開日 2023-10-25 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Recognition and reprogramming of E3 ubiquitin ligase surfaces by alpha-helical peptides. Nat Commun, 14, 2023
3T7U	A NeW Crystal structure of APC-ARM 分子名称: Adenomatous polyposis coli protein, PHOSPHATE ION 著者 Zhang, Z, Wu, G. 登録日 2011-07-31 公開日 2011-12-14 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystal structure of the armadillo repeat domain of adenomatous polyposis coli which reveals its inherent flexibility Biochem.Biophys.Res.Commun., 412, 2011
8FUC	Crystal structure of mouse Importin alpha in complex with Hendra virus matrix protein minor site NLS2 分子名称: Contaminant peptide KKLARE, Importin subunit alpha-1, Matrix protein 著者 Donnelly, C.M, Basler, C.F, Scott, C, Forwood, J.K. 登録日 2023-01-17 公開日 2023-01-25 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Henipavirus Matrix Protein Employs a Non-Classical Nuclear Localization Signal Binding Mechanism. Viruses, 15, 2023

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