PDB: 934 件ウェブページステータス検索Chemie searchBIRD

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7W5A	The cryo-EM structure of human pre-C*-II complex 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... 著者 Zhan, X, Lu, Y, Shi, Y. 登録日 2021-11-29 公開日 2022-06-22 最終更新日 2022-08-17 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Mechanism of exon ligation by human spliceosome. Mol.Cell, 82, 2022
7W5B	The cryo-EM structure of human C* complex 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... 著者 Zhan, X, Lu, Y, Shi, Y. 登録日 2021-11-29 公開日 2022-06-22 最終更新日 2022-08-17 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Mechanism of exon ligation by human spliceosome. Mol.Cell, 82, 2022
7S7B	Human Nuclear exosome targeting (NEXT) complex homodimer bound to RNA (substrate 1) 分子名称: Exosome RNA helicase MTR4, RNA (46-MER), RNA-binding protein 7, ... 著者 Puno, M.R, Lima, C.D. 登録日 2021-09-15 公開日 2022-06-15 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (4.06 Å) 主引用文献 Structural basis for RNA surveillance by the human nuclear exosome targeting (NEXT) complex. Cell, 185, 2022
7S7C	Human Nuclear Exosome Targeting (NEXT) complex bound to RNA (substrate 2) 分子名称: Exosome RNA helicase MTR4, RNA (30-MER), RNA-binding protein 7, ... 著者 Puno, M.R, Lima, C.D. 登録日 2021-09-15 公開日 2022-06-15 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.62 Å) 主引用文献 Structural basis for RNA surveillance by the human nuclear exosome targeting (NEXT) complex. Cell, 185, 2022
7S3A	Crystal structure of intact U2AF65 RRM-region bound to AdML-C5 oligonucleotide 分子名称: DNA/RNA (5'-R(P*UP*UP*(UD)P*CP*U)-D(P*(BRU))-R(P*CP*C)-3'), SODIUM ION, Splicing factor U2AF 65 kDa subunit 著者 Jenkins, J.L, Henderson, S, Kielkopf, C.L. 登録日 2021-09-05 公開日 2022-05-25 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.48 Å) 主引用文献 Pre-mRNA splicing factor U2AF2 recognizes distinct conformations of nucleotide variants at the center of the pre-mRNA splice site signal. Nucleic Acids Res., 50, 2022
7S3B	Crystal structure of intact U2AF65 RRM-region bound to AdML-G5 oligonucleotide 分子名称: DI(HYDROXYETHYL)ETHER, DNA/RNA (5'-R(P*UP*UP*(UD)P*GP*U)-D(P*(BRU))-R(P*CP*C)-3'), Splicing factor U2AF 65 kDa subunit 著者 Jenkins, J.L, Henderson, S, Kielkopf, C.L. 登録日 2021-09-05 公開日 2022-05-25 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Pre-mRNA splicing factor U2AF2 recognizes distinct conformations of nucleotide variants at the center of the pre-mRNA splice site signal. Nucleic Acids Res., 50, 2022
7S3C	Crystal structure of intact U2AF65 RRM-region bound to AdML-A5 oligonucleotide 分子名称: DNA/RNA (5'-R(P*UP*UP*(UD)P*AP*U)-D(P*(BRU))-R(P*CP*C)-3'), Splicing factor U2AF 65 kDa subunit 著者 Glasser, E, Jenkins, J.L, Kielkopf, C.L. 登録日 2021-09-05 公開日 2022-05-25 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.51 Å) 主引用文献 Pre-mRNA splicing factor U2AF2 recognizes distinct conformations of nucleotide variants at the center of the pre-mRNA splice site signal. Nucleic Acids Res., 50, 2022
7QP6	Structure of the human 48S initiation complex in open state (h48S AUG open) 分子名称: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Yi, S.-H, Petrychenko, V, Schliep, J.E, Goyal, A, Linden, A, Chari, A, Urlaub, H, Stark, H, Rodnina, M.V, Adio, S, Fischer, N. 登録日 2022-01-03 公開日 2022-05-11 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (4.7 Å) 主引用文献 Conformational rearrangements upon start codon recognition in human 48S translation initiation complex. Nucleic Acids Res., 50, 2022
7QP7	Structure of the human 48S initiation complex in closed state (h48S AUG closed) 分子名称: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Yi, S.-H, Petrychenko, V, Schliep, J.E, Goyal, A, Linden, A, Chari, A, Urlaub, H, Stark, H, Rodnina, M.V, Adio, S, Fischer, N. 登録日 2022-01-03 公開日 2022-05-11 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Conformational rearrangements upon start codon recognition in human 48S translation initiation complex. Nucleic Acids Res., 50, 2022
7Q4L	The solution structure of hsDND1 RRM12 bound to CUUAUUUG RNA 分子名称: Dead end protein homolog 1, RNA (5'-R(*CP*UP*UP*AP*UP*UP*UP*G)-3') 著者 Duszczyk, M.M, Allain, F.H.T. 登録日 2021-10-31 公開日 2022-05-04 最終更新日 2024-06-19 実験手法 SOLUTION NMR 主引用文献 The solution structure of Dead End bound to AU-rich RNA reveals an unusual mode of tandem RRM-RNA recognition required for mRNA regulation. Nat Commun, 13, 2022
7ZEX	Complex Cyp33-RRMdelta alpha : UAAUGUCG RNA 分子名称: Isoform 3 of Peptidyl-prolyl cis-trans isomerase E, RNA (5'-R(*UP*AP*AP*UP*GP*UP*CP*G)-3') 著者 Blatter, M, Allain, F, Meylan, C. 登録日 2022-03-31 公開日 2022-05-04 最終更新日 2024-06-19 実験手法 SOLUTION NMR 主引用文献 RNA binding induces an allosteric switch in Cyp33 to repress MLL1-mediated transcription. Sci Adv, 9, 2023
7ZEY	Complex Cyp33-RRM : MLL1-PHD3 分子名称: MLL cleavage product N320, Peptidyl-prolyl cis-trans isomerase E, ZINC ION 著者 Blatter, M, Allain, F, Meylan, C. 登録日 2022-03-31 公開日 2022-04-13 最終更新日 2024-06-19 実験手法 SOLUTION NMR 主引用文献 RNA binding induces an allosteric switch in Cyp33 to repress MLL1-mediated transcription. Sci Adv, 9, 2023
7ZEZ	Trimolecular complex Cyp33-RRMdelta alpha : MLL1-PHD3 : H3K4me3 分子名称: Histone H3, Isoform 3 of Peptidyl-prolyl cis-trans isomerase E, MLL cleavage product N320, ... 著者 Blatter, M, Allain, F, Meylan, C. 登録日 2022-03-31 公開日 2022-04-13 最終更新日 2023-05-03 実験手法 SOLUTION NMR 主引用文献 RNA binding induces an allosteric switch in Cyp33 to repress MLL1-mediated transcription. Sci Adv, 9, 2023
7ZEV	Free form of extended Cyp33-RRM 分子名称: Peptidyl-prolyl cis-trans isomerase E 著者 Blatter, M, Allain, F, Meylan, C. 登録日 2022-03-31 公開日 2022-04-13 最終更新日 2024-06-19 実験手法 SOLUTION NMR 主引用文献 RNA binding induces an allosteric switch in Cyp33 to repress MLL1-mediated transcription. Sci Adv, 9, 2023
7ZEW	Complex Cyp33-RRM : AAUAAA RNA 分子名称: Peptidyl-prolyl cis-trans isomerase E, RNA (5'-R(*AP*AP*UP*AP*AP*A)-3') 著者 Blatter, M, Allain, F, Meylan, C. 登録日 2022-03-31 公開日 2022-04-13 最終更新日 2024-06-19 実験手法 SOLUTION NMR 主引用文献 RNA binding induces an allosteric switch in Cyp33 to repress MLL1-mediated transcription. Sci Adv, 9, 2023
7SLQ	Cryo-EM structure of 7SK core RNP with circular RNA 分子名称: 7SK snRNA methylphosphate capping enzyme, La-related protein 7, Minimal circular 7SK RNA, ... 著者 Yang, Y, Liu, S, Zhou, Z.H, Feigon, J. 登録日 2021-10-24 公開日 2022-03-30 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structural basis of RNA conformational switching in the transcriptional regulator 7SK RNP. Mol.Cell, 82, 2022
7SLP	Cryo-EM structure of 7SK core RNP with linear RNA 分子名称: 7SK snRNA methylphosphate capping enzyme, La-related protein 7, Linear 7SK RNA, ... 著者 Yang, Y, Liu, S, Zhou, Z.H, Feigon, J. 登録日 2021-10-24 公開日 2022-03-30 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Structural basis of RNA conformational switching in the transcriptional regulator 7SK RNP. Mol.Cell, 82, 2022
7Q4O	Substrate-bound A-like U2 snRNP 分子名称: BPS oligo, PHD finger-like domain-containing protein 5A, Splicing factor 3A subunit 2, ... 著者 Tholen, J, Galej, W.P. 登録日 2021-11-01 公開日 2022-03-30 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (2.1 Å) 主引用文献 Structural basis of branch site recognition by the human spliceosome. Science, 375, 2022
7Q3L	Human 17S U2 snRNP 5' domain 分子名称: HIV Tat-specific factor 1, PHD finger-like domain-containing protein 5A, Probable ATP-dependent RNA helicase DDX46, ... 著者 Tholen, J, Galej, W.P. 登録日 2021-10-28 公開日 2022-03-30 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (2.21 Å) 主引用文献 Structural basis of branch site recognition by the human spliceosome. Science, 375, 2022
7PU5	Structure of SFPQ-NONO complex 分子名称: MAGNESIUM ION, Non-POU domain-containing octamer-binding protein, Splicing factor, ... 著者 Fribourg, S. 登録日 2021-09-28 公開日 2022-03-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.999 Å) 主引用文献 Crystal structure of SFPQ-NONO heterodimer. Biochimie, 198, 2022
7PY2	Structure of pathological TDP-43 filaments from ALS with FTLD 分子名称: TAR DNA-binding protein 43 著者 Arseni, D, Hasegawa, H, Murzin, A.G, Kametani, F, Arai, M, Yoshida, M, Falcon, B. 登録日 2021-10-08 公開日 2021-12-15 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (2.59 Å) 主引用文献 Structure of pathological TDP-43 filaments from ALS with FTLD. Nature, 601, 2022
7EB1	Solution NMR structure of the RRM domain of RNA binding protein RBM3 from homo sapiens 分子名称: RNA-binding protein 3 著者 Boral, S, Roy, S, Basak, A.J, Maiti, S, Lee, W, De, S. 登録日 2021-03-08 公開日 2021-12-08 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structural and dynamic studies of the human RNA binding protein RBM3 reveals the molecular basis of its oligomerization and RNA recognition. Febs J., 289, 2022
7OHR	Nog1-TAP associated immature ribosomal particle population E from S. cerevisiae 分子名称: 25S rRNA, 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ... 著者 Milkereit, P, Poell, G. 登録日 2021-05-11 公開日 2021-11-10 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (4.72 Å) 主引用文献 Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors. Plos One, 16, 2021
7OHQ	Nog1-TAP associated immature ribosomal particle population C from S. cerevisiae 分子名称: 25S rRNA, 5.8S rRNA, 5S rRNA, ... 著者 Milkereit, P, Poell, G. 登録日 2021-05-11 公開日 2021-11-03 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors. Plos One, 16, 2021
7OHP	Nog1-TAP associated immature ribosomal particles from S. cerevisiae after rpL25 expression shut down, population A 分子名称: 25S rRNA, 5.8S rRNA, 60S ribosomal protein L13-A, ... 著者 Milkereit, P, Poell, G. 登録日 2021-05-11 公開日 2021-11-03 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors. Plos One, 16, 2021

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