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4EYD
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Human Insulin
分子名称: CHLORIDE ION, Insulin A chain, Insulin B chain, ...
著者Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R.
登録日2012-05-01
公開日2013-05-01
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (1.471 Å)
主引用文献Structural meta-analysis of regular human insulin in pharmaceutical formulations.
Eur J Pharm Biopharm, 85, 2013
4EWZ
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BU of 4ewz by Molmil
Human Insulin
分子名称: CHLORIDE ION, Insulin A chain, Insulin B chain, ...
著者Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R.
登録日2012-04-29
公開日2013-05-01
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (1.791 Å)
主引用文献Structural meta-analysis of regular human insulin in pharmaceutical formulations.
Eur J Pharm Biopharm, 85, 2013
2M2N
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BU of 2m2n by Molmil
Structure of [L-HisB24] insulin analogue at pH 8.0
分子名称: Insulin A chain, Insulin B chain
著者Zakova, L, Veverka, V, Jiracek, J.
登録日2012-12-29
公開日2013-03-06
最終更新日2013-06-05
実験手法SOLUTION NMR
主引用文献Structural integrity of the B24 site in human insulin is important for hormone functionality.
J.Biol.Chem., 288, 2013
2M2O
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Structure of [D-HisB24] insulin analogue at pH 1.9
分子名称: Insulin A chain, Insulin B chain
著者Zakova, L, Veverka, V, Jiracek, J.
登録日2012-12-29
公開日2013-03-06
最終更新日2013-06-05
実験手法SOLUTION NMR
主引用文献Structural integrity of the B24 site in human insulin is important for hormone functionality.
J.Biol.Chem., 288, 2013
3ZI3
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BU of 3zi3 by Molmil
Crystal structure of the B24His-insulin - human analogue
分子名称: INSULIN, SULFATE ION
著者Zakova, L, Kletvikova, E, Veverka, V, Lepsik, M, Watson, C.J, Turkenburg, J.P, Jiracek, J, Brzozowski, A.M.
登録日2013-01-02
公開日2013-03-06
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural Integrity of the B24 Site in Human Insulin is Important for Hormone Functionality
J.Biol.Chem., 288, 2013
2M2P
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BU of 2m2p by Molmil
Structure of [D-HisB24] insulin analogue at pH 8.0
分子名称: Insulin A chain, Insulin B chain
著者Zakova, L, Veverka, V, Jiracek, J.
登録日2012-12-29
公開日2013-03-06
最終更新日2013-06-05
実験手法SOLUTION NMR
主引用文献Structural integrity of the B24 site in human insulin is important for hormone functionality.
J.Biol.Chem., 288, 2013
2M2M
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BU of 2m2m by Molmil
Structure of [L-HisB24] insulin analogue at pH 1.9
分子名称: Insulin A chain, Insulin B chain
著者Zakova, L, Veverka, V, Jiracek, J.
登録日2012-12-28
公開日2013-03-06
最終更新日2013-06-05
実験手法SOLUTION NMR
主引用文献Structural integrity of the B24 site in human insulin is important for hormone functionality.
J.Biol.Chem., 288, 2013
2M1E
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Biosynthetic engineered B28K-B29P human insulin monomer structure in in water solutions.
分子名称: Insulin
著者Bocian, W, Kozerski, L.
登録日2012-11-26
公開日2013-02-27
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Biosynthetic engineered B28(K)-B29(P) human insulin monomer structure in water and in water/acetonitrile solutions.
J.Biomol.Nmr, 55, 2013
2M1D
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Biosynthetic engineered B28K-B29P human insulin monomer structure in in water/acetonitrile solutions.
分子名称: Insulin
著者Bocian, W, Kozerski, L.
登録日2012-11-26
公開日2013-02-27
最終更新日2013-05-22
実験手法SOLUTION NMR
主引用文献Biosynthetic engineered B28(K)-B29(P) human insulin monomer structure in water and in water/acetonitrile solutions.
J.Biomol.Nmr, 55, 2013
4IUZ
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BU of 4iuz by Molmil
High resolution crystal structure of racemic ester insulin
分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, Insulin A chain, ...
著者Avital-Shmilovici, M, Mandal, K, Gates, Z.P, Phillips, N, Weiss, M.A, Kent, S.B.H.
登録日2013-01-22
公開日2013-02-13
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Fully Convergent Chemical Synthesis of Ester Insulin: Determination of the High Resolution X-ray Structure by Racemic Protein Crystallography.
J.Am.Chem.Soc., 135, 2013
4FKA
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BU of 4fka by Molmil
High resolution structure of the manganese derivative of insulin
分子名称: Insulin A chain, Insulin B chain, MANGANESE (II) ION, ...
著者Prugovecki, B, Pulic, I, Toth, M, Matkovic-Calogovic, D.
登録日2012-06-13
公開日2013-02-13
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.08 Å)
主引用文献High Resolution Structure of the Manganese Derivative of Insulin
Croat.Chem.Acta, 85, 2012
3W11
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Insulin receptor ectodomain construct comprising domains L1-CR in complex with human insulin, Alpha-CT peptide(704-719) and FAB 83-7
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin A chain, Insulin B chain, ...
著者Lawrence, M.C, Smith, B.J.
登録日2012-11-06
公開日2013-01-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献How insulin engages its primary binding site on the insulin receptor
Nature, 493, 2013
4AKJ
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Ligand controlled assembly of hexamers, dihexamers, and linear multihexamer structures by an engineered acylated insulin
分子名称: CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN, ...
著者Steensgaard, D.B, Schluckebier, G, Strauss, H.M, Norrman, M, Thomsen, J.K, Friderichsen, A.V, Havelund, S, Jonassen, I.
登録日2012-02-23
公開日2013-01-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Ligand Controlled Assembly of Hexamers, Dihexamers, and Linear Multihexamer Structures by the Engineered Acylated Insulin Degludec.
Biochemistry, 52, 2013
4AJZ
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BU of 4ajz by Molmil
Ligand controlled assembly of hexamers, dihexamers, and linear multihexamer structures by an engineered acylated insulin
分子名称: CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN, ...
著者Steensgaard, D.B, Schluckebier, G, Strauss, H.M, Norrman, M, Thomsen, J.K, Friderichsen, A.V, Havelund, S, Jonassen, I.
登録日2012-02-21
公開日2013-01-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Ligand Controlled Assembly of Hexamers, Dihexamers, and Linear Multihexamer Structures by the Engineered Acylated Insulin Degludec.
Biochemistry, 52, 2013
4AK0
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BU of 4ak0 by Molmil
Ligand controlled assembly of hexamers, dihexamers, and linear multihexamer structures by an engineered acylated insulin
分子名称: INSULIN A CHAIN, INSULIN B CHAIN
著者Steensgaard, D.B, Schluckebier, G, Strauss, H.M, Norrman, M, Thomsen, J.K, Friderichsen, A.V, Havelund, S, Jonassen, I.
登録日2012-02-21
公開日2013-01-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Ligand Controlled Assembly of Hexamers, Dihexamers, and Linear Multihexamer Structures by the Engineered Acylated Insulin Degludec.
Biochemistry, 52, 2013
4AJX
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BU of 4ajx by Molmil
Ligand controlled assembly of hexamers, dihexamers, and linear multihexamer structures by an engineered acylated insulin
分子名称: IMIDAZOLE, INSULIN, N-(16-Carboxyhexadecanoyl)-L-glutamic acid, ...
著者Steensgaard, D.B, Schluckebier, G, Strauss, H.M, Norrman, M, Thomsen, J.K, Friderichsen, A.V, Havelund, S, Jonassen, I.
登録日2012-02-20
公開日2013-01-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Ligand Controlled Assembly of Hexamers, Dihexamers, and Linear Multihexamer Structures by the Engineered Acylated Insulin Degludec.
Biochemistry, 52, 2013
3V19
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BU of 3v19 by Molmil
Forestalling insulin fibrillation by insertion of a chiral clamp mechanism-based application of protein engineering to global health
分子名称: CHLORIDE ION, Insulin, PHENOL, ...
著者Wan, Z.L, Hua, Q.X, Wickramasinghe, N.P, Huang, K, Petkova, A.T, Hu, S.Q, Phillips, N.B, Yeh, I.J, Whittake, J, Ismail-Beigi, F, Katsoyyannis, P.G, Tycko, R, Weiss, M.A.
登録日2011-12-09
公開日2012-12-12
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Forestalling insulin fibrillation by insertion of a chiral clamp mechanism-based application of protein engineering to global health
To be Published
3V1G
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BU of 3v1g by Molmil
Forestalling insulin fibrillation by insertion of a chiral clamp mechanism-based application of protein engineering to global health
分子名称: CHLORIDE ION, Insulin, PHENOL, ...
著者Wan, Z.L, Hua, Q.X, Wickramasinghe, N.P, Huang, K, Petkova, A.T, Hu, S.Q, Phillips, N.B, Yeh, I.J, Whittake, J, Ismail-Beigi, F, Katsoyyannis, P.G, Tycko, R, Weiss, M.A.
登録日2011-12-09
公開日2012-12-12
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Forestalling insulin fibrillation by insertion of a chiral clamp mechanism-based application of protein engineering to global health
To be Published
3ROV
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BU of 3rov by Molmil
Insulin's biosynthesis and activity have opposing structural requirements: a new factor in neonatal diabetes mellitus
分子名称: CHLORIDE ION, Insulin, PHENOL, ...
著者Weiss, M.A, Wan, Z.L, Dodson, E.J, Liu, M, Xu, B, Hua, Q.X, Turkenburg, M, Whittingham, J, Nakagawa, S.H, Huang, K, Hu, S.Q, Jia, W.H, Wang, S.H, Brange, J, Whittaker, J, Arvan, P, Katsoyannis, P.G, Dodson, G.G.
登録日2011-04-26
公開日2012-05-02
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Insulin's biosynthesis and activity have opposing structural requirements: a new factor in neonatal diabetes mellitus
To be Published
3U4N
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BU of 3u4n by Molmil
A novel covalently linked insulin dimer
分子名称: Insulin A chain, Insulin B chain
著者Norrman, M, Vinther, T.N.
登録日2011-10-10
公開日2012-04-11
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Novel covalently linked insulin dimer engineered to investigate the function of insulin dimerization.
Plos One, 7, 2012
2LGB
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BU of 2lgb by Molmil
Modified A22Gly-B31Arg Human Insulin
分子名称: Insulin A chain, Insulin B chain
著者Bocian, W, Kozerski, L.
登録日2011-07-25
公開日2012-04-11
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Recombinant A22(G)-B31 (R)-human insulin. A22 addition introduces conformational mobility in B chain C-terminus.
J.Biomol.Nmr, 52, 2012
4E7V
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BU of 4e7v by Molmil
The structure of R6 bovine insulin
分子名称: CHLORIDE ION, Insulin A chain, Insulin B chain, ...
著者Harris, P, Frankaer, C.G, Knudsen, M.V.
登録日2012-03-19
公開日2012-04-04
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The structures of T(6), T(3)R(3) and R(6) bovine insulin: combining X-ray diffraction and absorption spectroscopy.
Acta Crystallogr.,Sect.D, 68, 2012
4E7T
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BU of 4e7t by Molmil
The structure of T6 bovine insulin
分子名称: Insulin A chain, Insulin B chain, ZINC ION
著者Harris, P, Frankaer, C.G, Knudsen, M.V.
登録日2012-03-19
公開日2012-04-04
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献The structures of T(6), T(3)R(3) and R(6) bovine insulin: combining X-ray diffraction and absorption spectroscopy.
Acta Crystallogr.,Sect.D, 68, 2012
4E7U
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BU of 4e7u by Molmil
The structure of T3R3 bovine insulin
分子名称: Insulin A chain, Insulin B chain, THIOCYANATE ION, ...
著者Harris, P, Frankaer, C.G, Knudsen, M.V.
登録日2012-03-19
公開日2012-04-04
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献The structures of T(6), T(3)R(3) and R(6) bovine insulin: combining X-ray diffraction and absorption spectroscopy.
Acta Crystallogr.,Sect.D, 68, 2012
2L29
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Complex structure of E4 mutant human IGF2R domain 11 bound to IGF-II
分子名称: Insulin-like growth factor 2 receptor variant, Insulin-like growth factor II
著者Williams, C, Hoppe, H, Rezgui, D, Strickland, M, Frago, S, Ellis, R.Z, Wattana-Amorn, P, Prince, S.N, Zaccheo, O.J, Forbes, B, Jones, E.Y, Crump, M.P, Hassan, A.B.
登録日2010-08-13
公開日2012-02-15
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献An exon splice enhancer primes IGF2:IGF2R binding site structure and function evolution.
Science, 338, 2012

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