3ZI3

Crystal structure of the B24His-insulin - human analogue

Summary for 3ZI3

Entry DOI	10.2210/pdb3zi3/pdb
Descriptor	INSULIN, SULFATE ION, ... (4 entities in total)
Functional Keywords	hormone
Biological source	HOMO SAPIENS (HUMAN) More
Cellular location	Secreted: P01308 P01308
Total number of polymer chains	2
Total formula weight	5904.69
Authors	Zakova, L.,Kletvikova, E.,Veverka, V.,Lepsik, M.,Watson, C.J.,Turkenburg, J.P.,Jiracek, J.,Brzozowski, A.M. (deposition date: 2013-01-02, release date: 2013-03-06, Last modification date: 2023-12-20)
Primary citation	Zakova, L.,Kletvikova, E.,Veverka, V.,Lepsik, M.,Watson, C.J.,Turkenburg, J.P.,Jiracek, J.,Brzozowski, A.M. Structural Integrity of the B24 Site in Human Insulin is Important for Hormone Functionality J.Biol.Chem., 288:10230-, 2013 Cited by PubMed: 23447530 DOI: 10.1074/JBC.M112.448050 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation